Download as docx, pdf, or txt
Download as docx, pdf, or txt
You are on page 1of 1

Diseases & Syndromes

:Sjögren's Syndrome

.Definition: a chronic, slowly progressive, inflammatory autoimmune disorder

.Description: * Dryness in the eye and mouth


:There are two types *
Primary; occurs by itself and is not associated with another autoimmune .1
disorder. (50% of the cases)
Secondary; occurs in the presence of a major underlying autoimmune .2
,connective tissue disease such as rheumatoid arthritis
.systemic lupus erythematosus, or scleroderma

:Causes: underlying causes


Chronic inflammation -
Cellular apoptosis -
Autonomic nervous system dysfunction -
Neurotransmitter abnormality -
Genetic predisposition -

:Signs & Symptoms: Related gland destruction symptoms


.Hardness in swallowing and talking -
.Dry mouth, no saliva; cavities in teeth thus its decay -
Eyes: become dry, itching, burning, redness, increased sensitivity -
to light and thick secretions gathering at the eye corners
.closest to the nose
The cornea may have small irritated pits in its surface
.)ulcerations(
.Enlarged parotid glands -
.Sinus: dryness, nosebleeds -
.Respiratory tract: ear infection, hoarseness, bronchitis, pneumonia -
.Gynecological: Vaginal dryness -
Dermatologic disorders: dry patches, vaculities, cutaneous B-cell -
.lymphoma
Pancreas, rarely, may slow production of enzymes important for -
.digestion
.Kidney/Bladder may malfunction -

:Unrelated gland destruction symptoms


Fatigue -
Decreased energy -
Fevers -
Muscle aches and pains -
Joint pain -

.Increased risk for depression and other mood disorders

You might also like