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KCHOOMicroposter
KCHOOMicroposter
IMMITIS
Kathryn Choo - Santa Clara University
REFERENCES
METHODS
Cutler, Jim E., and Keith H. Erke. "Ultrastructural
Figure 6. Septum of Coccidioides immitis. Electron-dense Woronin-like
Characteristics of Coccidioides Immitis, a
Three separate experiments performed by different researchers all combine to
the overall support of increased infection of coccidiomyocosis seen in pregnant bodies indicated by arrows. Bar indicates 1.0 AM.
Morphological Variant of Cryptococcus Neoformans
women and men due to human sex hormone levels effects on fungal growth and and Podosypha Ravenelli V." Journal of Bacteriology
maturation.
105.1 (1971): 438-44. Print.
Experiment 1 Powell, Bernard L., David J. Drutz, Milton Huppert,
In 1981 Researchers at the University of Texas measured the effects of
different sex hormones on the growth and maturation of C. immitis along with a
and Sung H. Sun. "Relationship of Progesterone- and
few other strains to test if it solely effects C. immitis. Along with the testing of Estradiol-Binding Proteins in Coccidioides Immitis to
sex hormones: testosterone, progesterone, and 17beta-estradiol, they also used
controls of the fungus in a compound with only ethanol or distilled water. Other Coccidioidal Dissemination in Pregnancy." Infection
test they performed included measuring the effects of sterols without sex hormone
activity (cholesterol and ergosterol) and non-steroidal anti-estrogens (tamoxifen
and Immunity 40.2 (1983): 478-85. Print.
and nafoxidine) to confirm the positive results of the sex hormones. They
obtained data of the logarithmic growth under these different conditions, Drutz, David J., Milton Huppert, Sung H. Sun, and
maturation percentage and also analyzed spore size.
William L. McGuire. "Human Sex Hormones
Experiment 2
Stimulate Growth and Maturation of Coccidioides
Exactly a decade before this experiment, in 1971, researchers at Tulane
University School of Medicine performed an experiment, obtaining electronic Immits." Infection and Immunity 32.2 (1981): 897-
microscopic images of the morphological structure of C. immitis. Their findings
on the structure of C. immitis provided more information allowing researchers to
907. Print.
study better the “imperfect” taxonomy of the fungus.
Experiment 3
Pan, Shuchong, Lynee Sigler, and Garry T. Cole.
An experiment performed in 1983 by the same researchers at the University
"Evidence for Phylogenetic Connection between
of Texas, further supported the relationship between sex hormones and its effect Coccidioides Immitis and Uncinocarpus Reesii
on C. immitis growth. They performed an experiment testing the binding affinity
of different fungal strains focusing on C. immitis cytosol on the different sex (Onygenaceae)." Microbiology 140 (1994): 1481-494.
hormones that showed positive effects on its fungal growth.
Print.