Physiology of Puberty

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PHYSIOLOGY OF PUBERTY

DR. NOR ASHIKIN


03/09 year 1

Endocrine control of puberty in males

• The testes secrete substantial amounts of testosterone in the 1st


trimester of fetal development and in the 1st few month of infancy.

• The testes then becomes dormant for the rest of infancy and
childhood

• From puberty to adulthood, reproductive functions is regulated by


hormonal links between the hypothalamus, pituitary gland and
gonads (the brain-testicular axis)
Endocrine controls of puberty in females

• Puberty is triggered by the same hypothalamic pituitary hormones


in girls as it is in boys

• Rising levels of GnRH stimulate the ant lobe of


pituitary to secrete FSH &
LH

• FSH help develop the ovarian follicles, which in


turn secrete estrogen,progesterone, inhibin and a
small amount of androgen

• These hormone levels rise gradually from ages 8 – 12


and more sharply early teens

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