PATHOPHYSIOLOGY

Precipitating Factors:
Hypertension Predisposing Factors:
Hyperlipidemia Life style (sedentary)
VASOCONSTRICTION
Diabetes Mellitus Vices (Alcohol, smoke)
Heart Diseases Age
Atherosclerosis Diet
Arteriosclerosis Sex
Thrombosis Heredity
Severe dehydration Blockage of the blood Self-medication
vessel
Embolism

Lack of oxygen & High blood pressure, smoking, heart

nutrients supply Ischemic diseases, diabetes, narrowing of
Stroke arteries supplying the brain, high
cholesterol and an unhealthy lifestyle.

Cerebral Ischemia
Hypoxia
Subarachnoid High blood pressure, smoking, and a
Hemorrhage family history of burst aneurysms.

- Cell death Altered cerebral

- Decreased metabolism Severe dehydration, severe infection
Oxygen level in the sinuses of the head and
Venous medical or genetic conditions that
Stroke increase a person’s tendency to form
blood clots.
Intracerebral Decreased
hemorrhage cerebral perfusion
Large Artery Hypertension, diabetes, smoking and
Strokes high cholesterol levels.

P Local
Acidosis
A
Transient
R Ischemic Same with Ischemic stroke
A Cytotoxic Attack
L Edema
Y Small Artery Hypertension, diabetes and
S Stroke smoking.
Aneurysm
I Rupture
S Irregular heart beat (atrial fibrillation),
Embolic a heart attack (myocardial infarction),
strokes heart failure or a small hole in the
heart called a PFO (Patent Foramen
Ovale).

Brain tissue
Necrosis

DEATH Severe Cases