CELL BIOLOGY

Prepared by
University of Wah
004
 Cell Membrane
• Membrane that
enclose cell
organelles, &
separate them from
the external
environment.
• Flexible & allows
movement
• Size: 7-10 nm wide
2
 Structure
FLUID MOSAIC MODEL

• FLUID- Movement of phospholipid molecules

• MOSAIC- Scattered protein molecules
 Membrane Components

 Phospholipids  Proteins
 Cholesterol  Carbohydrates
 Semi permeable Membrane

 Maintain Homeostasis.
 Functions of Plasma
Membrane
 Protective barrier & selectively
permeable
Provide anchoring sites for filaments
of cytoskeleton
Interlocking surfaces bind cells
together (junctions)
6
 Types of Transport
Across Cell Membranes

7
Three Forms of Transport Across the Membrane

8
 DIFFUSION
Simple Osmosis:-
Diffusion:- • Diffusion of water
• Molecules move across a
from area of membrane
HIGH to LOW
concentration
What Happens to Blood Cells?

10
 FACILITATED DIFFUSION
Channel Proteins: Carrier proteins:-
• Through the pores • By changing shape
 ACTIVE TRANSPORT
Example:
• Na+-K+ Pump
 3 Na+
pumped in
for every
2 K+
pumped
out;
Creates a
membrane
potential
 BULK TRANSPORT
Import &
Export
of large
molecules

A. Endocytosis B. Phagocytosis C. Exocytosis

 Pinocytosis
• Cell take in
dissolved material

• Through
invagination

• Called “Cell
Drinking”
Receptor-Mediated Endocytosis
 Some
integral
proteins have
receptors on
their surface

 To recognize
& take in
hormones,
cholesterol,
etc.
 Phagocytosis
 Called “Cell
Eating”

 Process in which
Cell engulf large
particles such
as food,
bacteria, etc.
into vesicles
 Exocytosis
 Opposite of endocytosis is exocytosis

 Residual bodies are thrown out of cell

 If cell membrane don’t
exist?
• No protection

• No communication inside body

• Lack of energy in body

• Ultimately cell death

Thank you for your attention

ANY
??QUESTION
?

!!!Best wishes