areCOVER Structure of gold nanoparticle in which the central atoms are packed ina decahedron, surrounded by aditional layers of gold atoms in unanticipated geometries. Gold atoms, qo; sultr atoms, blue; carbon atoms, white; oxygen atoms, red; the superimposed red mesh depicts Volume 318, issue 5849 DEPARTMENTS Science Online This Week in Science Editors” Choice Contact Science Random Samples Newsmakers the elecion-density dstibution determined by xray aysallography. See page 430. ‘Image: Pablo D.Jadrinsky and Guillermo Celero NEWS OF THE WEEK Nobel Peace Prize Won by Host of Scientists and 372 ‘One Crus CChemitry Laureate Planaated New Schoo of thought Three Economists Lauded for Theory That Halps the Invisible Hand SCIENCESCOPE 2 Natural Selection, Not Chance, Pats the 376 ‘Desert Landscape Coastal Atfcts Suggest Early Beginnings for 377 Modern Behavior Space Sighting Suggests Stardust Doesn'tHaveto 379 Come From Stars U.K. Spells Out Boos in Mezal Research 379 NEWS FOCUS Location, Location, Location 380 Fresh Evidence Points to an Old Suspect Calcium 384 Dirty Science Soll Forensics Digs nio New Techniques 386 In Search ofthe Works Most Ancient Mariners rt wormsciencemag.org SCIENCE Since Cateers EDITORIAL 359 Feeding a Hungry Workd by Norman Berloug LETTERS Of Aging Mice and Men. Ailer 390 Response, Liu and. Finkel Replicating Genome-Wide Assocation Studies 'N. H. Kurhoim Response D. 8. Goldstein ‘AMleasure of Respect for Translational Research 4. Sharma CORRECTIONS AND CLARIFICATIONS BOOKS Er AL AFarewel to Alms Bret Economic Histor of ‘the World G Clark reviewed by S. Bonles ‘Me We Ready? Public Health Since 9/41 1D. Rosner and G. Markowit, reviewed by B.S, Keim POLICY FORUM The Science and ausiness of Genetic Ancestry Testing DA, Bolick et al. PERSPECTIVES Sampling the Sun K Marth 399 Clemberg AG. Rvenbork ord 8.0. Schl Simmering, Not Boing CR Kaiser wy LF landneber 2 Nano-Golden Order RL. Whetten ond R.C. Price CONTENTS corsinued >> VOL318 19 OCTOBER 2007 347Science SCIENCE EXPRESS CELL BIOLOGY Bifunctional Bacterial Protein Links GD Displacement to Rabl Activation ‘MP Aochner ond R. Risberg The bacterium that causes Legionnaires dicaserenits ahost protein that ragultes vei trafic by mining hes actating proteins TOU 26lcienee 1149121 Generics Genome‘ Experimental Determination of Barriers to Horizontal Gene Transfer R.Sorek etal. Charadteratn of gene fame that canna be cenedn the cmnman bate Escherichia col sages that iareased dose and expression of erin genes te ‘axe tthe host 1O.1126cieree-1167 112 TECHNICAL COMMENT ABSTRACTS NEUROSCIEN Comment on "Human Neuroblasts Migrate tothe Olfactory Gub via a Lateral Ventricular Extension” W.Sanai etal, Response to Comment on "Human Neureblasts Migiate tothe Ollactry Bulb viaa Lateral Ventricular Extension” MA Cortiseta REVIEW MATHEMATES ‘Mathematics and Complex Systems a. Foote BREVIA GENETICS Mitechonstial ONA as a Genomic igsan Puzzle W. Norende ond 6. Burger The mitochon gnes ofthe nical oukayote Diplonema are fragmented aceg mony sll vemosores andthe cekng RNAS ae fiecedtogetha te orm messanger MAS. a5 cone wunmsciencemag.org SCIENCE VOL318 CONTENTS q GENETICS |AB-Defensin Mutation Causes Slack Coat Color in Domestic Dogs S.1. Condile etal \dentfcation ofa gene causing Hack coat cola in dogs eval suprising new roe fora potty preveusy lpia in the bodys dfence aganat microbes, 10,11 26'sience 1147880 RESEARCH ARTICLES GEOCHEMISTRY ‘Mass-Dependent and Independent Fractionation of, 1g leotepes by Photoreduction in Aquatic Systems B.A. Beroquist and]. D. Blum Tho ce otpos of mor a Kadianated ina mac-ndopandert ‘anner during photoreductan, providing a racer of recur species and reactions tveugh ood webs 417 GENETICS Paired-End Mapping Reveals Extensive Structural Variation in the Human Genome 1.0. Korbel eat. Sequsaciag of stucurevariains eer segments of DNA Fam re inves of iferet thn roups showed espace ewes of 220 diversity REPORTS MATERIALS SCIENCE Mussetinspired Surtace Chemistry for 426 ‘attifunctional Coatings H. Lee, $M. Dellatore, W. M. Miler, PB. Messrsmith ‘Aide vig ofsurlces can be coated tha sth asc epanine solo, creating a uivesal adhere tha canbe realy modified by secondary reacts ucture 430 Structure of aThiol Monclayer—Protected GoidNareparide at 1A Resolution PD. Jadzinshy etal. Paxtiescontaeing 102 gold atoms Bound ts 44 organoular rolecaies can be gomn uifornl allowing xray resolution of thoi pure gold cre and chal uct 2.402, PLANETARY SCIENCE Constraints on Neon and Bigon Isotopic Fractionation 433 Solar Wine A. Mesbik etal Neen ané sigan etopic alos ems the sme throughout the salar ind in saroples etary Genes, uling et some solar adel that pesictsderaege CONTENTS corsinued >> 19 OCTOBER 2007 349