Biotechnology by using

microorganism

GROUP 7
Traditional Modern
Biotechnology Biotechnology

MICROORGANISM
 The reasons of Microorganism Metal from
using metal ore
as the food
microorganism separator
source
Microorganism

Plant pest WASTE

Medicine producer
microorganism control CULTIVATE
microorganism MICROORGANI
SM

VaCCinE AntibiotiCS Singular

cell protein
THE REASON OF
USING
MICROORGANIS
M
• Rapid growth
• The cells have a high protein content
• Can use waste products as the substrates, for
example from agricultural waste
• produce products which are not toxic
• As living organisms, biochemical reactions
controlled by the organism enzyme itself so
that does not require any additional external
reactant
Food and B e v e r a g e
Changer and
Producer
M i c ro or g an i sm
 n a lte r the
n i s m s c a e ra g e i n
c r o o rga o d / b e v
• M i lu e o ff o
t io n a l v a s
nu tr i n p r o c e s
e n ta t io
the ferm to
l e : e a n s in
Examp th a t tu r n s s oyb
o s p ora.
n t a t i o n o f N e u r
• Fer m e a d diti o n
w i th th e a u c e
onc o m h / so y s
t o te m p e
n s in
• soybea i n e
e s in t o w w i ne
• g r a p to bl ac k
i c k y ri c e
k s t
• blac
Mikroo r g a n is m e
sebag ai s u m be r
makanan
• The mass of microorganisms can
grow up to be two-fold within 1
hour, whereas the mass of plants or
animals need in weeks
• Minimal microbial mass contains
40% protein and contain high
vitamins and minerals
SINGULAR CELL PROTEIN

Definiton Example
Protein-rich foods derived Fusarium graminearum
from microorganisms Chorela
Candida utilis
Spirulina maxima
Saccharomices cereviceae
MEDICINE PRODUCER
MICROORGANISM
Antibiotics
 Antibiotics are compounds
produced a microorganism to
inhibit the growth of other
microorganism . 4 groups of
antibiotics:
Penicillin, Cephalosporin,
Tetracycline, Eritromicyn
 PENICILLIN

 The main component is a penicillin G

 Pros:
The existence of the range at penicillin
allow health staff to select the type of
treatment best suited to a particular
disease.
 CEPHALOSPORIN

 Produced by the fungus Cephalosporium

(1948)
 Cephalosporin active for bacteria that have
a character with range = ± penicillin.
Newest cephalosporin's are very effective
against bacteria resistant to penicillin.
 TETRACYCLINE

 Produced Streptomycin aureofacien.

 Active against bacteria that have a
character with range = ± penicillin.
 Tetracycline bind to calcium and
accumulated in the bones and teeth that
are developing
 ERITROMICYN

 It has a range of = ± penicillin.

 Useful to against the bacteria which are
resistant to penicillin or can be used for
allergic to penicillin
VACCINE
• The vaccine is a microorganism or
the microorganism which has been
weakened.
• The vaccine injected (with injection
/ oral) into the human body for the
human immune system active
against these microorganisms.
VACCINE SOURCE
DEATH MICROORGANISM
 Used to produce vaccines from bacteria that
cause whooping cough. The bacteria are
turned off by heating / use of chemical
compounds for their denaturized enzymatic
WEAKENED ORGANISM

 Vaccines produced from microorganisms that

have been attenuated are called attenuation
vaccine. Example: vaccines against
tuberculosis and poliomyelitis.
THE MICROORGANISM SUBSTANCE
WHICH DOES NOT CAUSE A DISEASE
 Example: diphtheria and tetanus toxoid
produced.
 Toxoid aims to stimulate antibody production,
but reduce their risk of infection by bacterial
pathogens.
Plant p e st c on t ro l
m i c ro o r g an i sm
 Bacillus thuringiencys (Bt) is a
bacterial pathogen of insects. Bt can
be found in the soil from the plant.
 Bt produces crystal proteins that can
kill insects and insect larvae or
caterpillars. Activity of Bt in plants
such as killing moths that become
pests in apple and pear fruit,
caterpillars on cabbage, broccoli, and
potatoes.
 EXAMPLE OF BT
BT’s Name Use
Bacillus thuringiensis varietas Attack Colorado potato beetle
tenebrionis and leaf beetle larvae
Bacillus thuringiensis Attacking various types of
varietas kurstaki worm farm crops
Bacillus thuringiensis varietas Attack mosquito and black
israelensis flies
Bacillus thuringiensis varietas Attacking moth larvae and
aizawa various caterpillars, especially
the Diamondback moth
caterpillars
Wast e C u l t i v a t e
mi c ro or g a n i sm
 Microorganisms help processing of
various types of waste, especially in the
decomposition of organic waste. The
main objective of wastewater treatment
is to reduce the content of BOD and
suspended solids.
Microorganisms wastewater through a
process in aerobic and anaerobic
decomposition.
Matter which consist of Carbon CO2

H2 S SO4 2-

NH4 + NO3-

Catalysis Process
 CULTIVATING BY ACTIVE
MUD

 wastewater treatment with aerobic bacteria

breed in a tank (tub) aerated waste with
the aim to reduce organic material
containing carbon or nitrogen in the
effluent.
 C6H12O2N2S + O2 + nutrient CO2
+ NH3 + C5H7NO2 + H2S + mud
 PROCESSING WITH FILTER
DROPS

 Waste water treatment using bio film technology.

Bio film is a layer of microorganisms that covered
the expanse of the filter at the bottom of the tank
waste.
Microorganism in bio films containing Vorticella
(protist) that live by eating bacteria and fungi, which
are useful to slow the decomposition process and
prevent the formation of slime layer on the filter
 MUD CATALYSIS

 That is the process of decomposition of

accumulated solids from the aerobic
processing or deposition of previous physical
treatment.
Anaerobic decomposition of sludge, such as
Methanobacterium.
M et a l f ro m M e ta l
o r e S e pa r a t o r
M i c ro o r g an i sm
 Used bacterium Thiobacillus
oxidans and T. ferroxidans in the
process of extraction of metals
because of the rich deposits are
much reduced, and the traditional
method of processing ore
(smelting) is a major cause of air
pollution.
C ON C LU S IO
N
 Biotechnology by using microorganism consist
of:
Traditional Modern
Bitechnology Technology
 Mikroorgani Mikroorgani
Alasan sme sebagai sme Pemisah
menggunakan sumber Logam dari
mikroorganisme makanan Bijih Logam

 The reason of using Microorganism:Mikroorganis

Mikroorganism
Mikroorganisme
• Rapid growth e Pembasmi
Penghasil Obat me Pengolah
Hama Tanaman
 High of protein contents
Limbah
 Can use the waste products as the substrate
 Clean products from toxic

 The biochemistry reaction controlled by organism

Vaksin
enzyme itself Antibiotik Protein sel
tunggal
 Microorganism has function as:

Medicine Producer Pest Plant Controll Waste cultivating

Food source Metal from metal Singular cell

ore separator protein

Vaccine Antibiotic