Predisposing Insulin Pancreas Alpha Cells

factor: deficiency
heredity
Glucagon
Decreased glucose-
induced insulin
secretion Glucagon
secreation

Precipitating factor: Ingested glucose

Diet cannot be used
Glycogenolysis

bAdgIrL™
Lifestyle
Modifications: glycogen
Full Diabetic Diet

Hepatic glucose
Metformin output
(Neoform) 500 mg
1 tab Qnoon PC 12
NN
Blood glucose
Level rise
Excess glucose molecules -HYPERGLYCEMIA-
attaches to Hgb

11/14/09
Gliclazide (Diamicron MR) 30
Glycosylatest Hgb
mg 1 tab QAM AC 6 AM
11.3% Sitaglipin + Metformin
(Janumet) 50/500 mg 1
tab BID PC 8Am-8PM
 Insulin Predisposing factor:
Resistance Heredity, age

Decrease tissue
responses to insulin Ketosteril 2 tab TID 8AM -
12NN – 6 PM

Deceased glucose Increase fat Muscle weight loss,

Increase protein
utilization mobilization wasting dry skin
utilization

bAdgIrL™
Fat metabolism Lifestyle
Modifications:
Full Diabetic Diet
Fatty acids
breakdown

Cholesterol and Ketone Accumulate

triglycerides formation in the blood

Excreted in the Produces H+ ion

Cholesterol packed w/ Blood becomes
urine
protein and lipoproteins Very acidic
Bind w/ bicarbonate
Ketonuria buffer in the blood
Plaque deposition large and
Coma &
small blood cells death
Serum
bicarbonate
Accelerated atherosclerosis

Poor circulation to pH of
pH
periphery body fluids
6.0
 Kidney

Kidney tubule
Cells cannot
Reabsorb fast
enough

Glucose begins to glucusuria

11/12/09 spill into the urine
RBC 3.5 M/cumm
Hgb 10.70 gm%
Hct 31.3 % Exerts osmotic
Pressure in the filltrate

bAdgIrL™
Increase of fluid Dehydration & Loss of H2O &
thirst polyuria
intake hypovolemia electrolytes

Weight
polydipsia Lack of nutrients Kalium durules 1
loss
entering cells tab QID 8AM -
11/14/09 12NN – 6 PM
Starvation K+ 2.71mEq/L
of cells Calcium 8.2 mg/dl

polyphagia
Chronic elevation of Increase viscosity Sluggish flow of Decrease peripheral Insufficient delivery of O2, WBC,
blood glucose of blood blood circulation nutrients, and antibodies

Prolonged increase
in venous pressure Impaired
immune function

Leaflets of the Precipitating factor:

Risk for infection

bAdgIrL™
venous valves are tissue injury
stretched and
prevented from
Presence of
closing completely
portal of entry

Allowing backflow or Bacteria release their

reflux of in the veins toxins in the subcutaneous
UTZ of both lower extremities;
tissue
Elevation of Edema (swelling)
Cilostazol (Trombocil) 100 mg 1 tab
legs BID Swelling, fever, localized
Skin discoloration Venous insufficiency
Skin ulcers redness
Cellulitis WBC 17,820/cumm
Segmenters 87%
Monocyte 7%

Ciprofloxacin (Sutid) 500 mg 1

cap BID PO 6 AM-6 PM
Clindamycin (300 mg) IVTT Q6H
ANST (-) 2 AM-8AM-2PM-8PM