MOLECULAR MODELLING, SYNTHESIS AND BIOLOGICAL

EVALUATION OF NOVEL SERIES OF MODIFIED FISETIN

DERIVATIVES

Phase-1 Project Submitted to

SRM UNIVERSITY
(Under section 3 of UGC act, 1956)
towards the partial fulfillment of degree of
MASTER OF PHARMACY
in
PHARMACEUTICAL CHEMISTRY
By

SWATHI.D
(Reg.No.2770913022)
Under the guidance of

Mrs.P.Valentina, M.Pharm., (Ph.D.)

Assistant Professor
Department Of Pharmaceutical Chemistry

SRM COLLEGE OF PHARMACY

Kattankulathur – 603203
Kanchipuram District
Tamil Nadu
DECEMBER 2010
 SRM UNIVERSITY
Established Under Section 3 of the UGC Act. 1956
SRM COLLEGE OF PHARMACY
KATTANKULATHUR-603203

CERTIFICATE
This is to certify that Ms.SWATHI.D of III semester (II year) M.Pharmacy in Pharmaceutical
Chemistry is undergoing project work entitled “MOLECULAR MODELING, SYNTHESIS
AND BIOLOGICAL EVALUATION OF NOVEL SERIES OF MODIFIED FISETIN
DERIVATIVES” at SRM College of Pharmacy from July 5th 2010 towards partial fulfillment
of degree of Master of pharmacy in Pharmaceutical Chemistry.

Mrs.P.Valentina, M.Pharm., (Ph.D.)

Guide

Dr.K.S.Lakshmi, M.Pharm., Ph.D.

Dean

Dr.K.Ilango, M.Pharm., Ph.D., FIC

Professor cum Head

Evaluated by
1)

2)
 CONTENTS

PAGENo.
CHAPTE TITLE
R
1 Introduction 1

2 Objective 22

3 Drug Profile 23

4 Literature Review 25

5 Validation 27

6 References 32