Pathophysiology: Precipitating Factors

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PATHOPHYSIOLOGY

Predisposing Factors:
Precipitating Factors:
 Age c. High-fat Diet
a. Hormone Replacement
 Gender d. Obesity
 Race e. Family hx. Therapy (Premarin)
 Lifestyle f. Anxiety
 Anovulation
 Early Menarche
a. Nulliparity b. Luteal Insuffiency
b. Use of oral contraceptives

ETIOLOGY:
Unknown

Estrogen Dominance S/Sx:


Treatment:
-swelling of
-GnRH
breasts
agonist
If not treated -depression
-Tamoxifen
-loss of sexual
-SERM
Proliferation of cells in drive
the uterus -dysmenorrhea

Overgrowth of the endometrial lining

Diagnostic Tests:
-Pelvic examination Development of uterine fibroid
-Ultrasonography

Interference in the vascular supply

Degeneration in the Sx:


interior part of the fibroid Hypermenorrhea

MYOMA

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