Scribd Logo
Upload

Welcome to Scribd!

  • Patho1 OBSTRUCTIVE JAUNDICE 2' CHOLEDOLITHIASIS, CHOLELITHIASIS

    Uploaded by

    Kyle Cholo Cholo
    1K views1 page
    This document discusses obstructive jaundice caused by cholelithiasis. It notes that cholelithiasis is predisposed by factors including being female, forty years old, fertile, fair-skinned, fat, and decreased bile acid synthesis in the liver alongside increased cholesterol synthesis. The formation of gallstones from supersaturated bile can then lead to bile stasis, biliary colic, nausea and vomiting, Murphy's sign, and jaundice as bile flow is obstructed and the gallbladder becomes inflamed.

    Original Description:

    Original Title

    patho1 OBSTRUCTIVE JAUNDICE 2’ CHOLEDOLITHIASIS, CHOLELITHIASIS

    Copyright

    © Attribution Non-Commercial (BY-NC)

    Available Formats

    DOCX, PDF, TXT or read online from Scribd

    Did you find this document useful?

    Is this content inappropriate?

    Report this Document
    This document discusses obstructive jaundice caused by cholelithiasis. It notes that cholelithiasis is predisposed by factors including being female, forty years old, fertile, fair-skinned, fat, and decreased bile acid synthesis in the liver alongside increased cholesterol synthesis. The formation of gallstones from supersaturated bile can then lead to bile stasis, biliary colic, nausea and vomiting, Murphy's sign, and jaundice as bile flow is obstructed and the gallbladder becomes inflamed.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as DOCX, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    Download as docx, pdf, or txt
    1K views1 page

    Patho1 OBSTRUCTIVE JAUNDICE 2' CHOLEDOLITHIASIS, CHOLELITHIASIS

    Uploaded by

    Kyle Cholo Cholo
    This document discusses obstructive jaundice caused by cholelithiasis. It notes that cholelithiasis is predisposed by factors including being female, forty years old, fertile, fair-skinned, fat, and decreased bile acid synthesis in the liver alongside increased cholesterol synthesis. The formation of gallstones from supersaturated bile can then lead to bile stasis, biliary colic, nausea and vomiting, Murphy's sign, and jaundice as bile flow is obstructed and the gallbladder becomes inflamed.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as DOCX, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    Download as docx, pdf, or txt
    of 1

    PATHOPHYSIOLOGY

    BOOKBASED

    OBSTRUCTIVE JAUNDICE 2’ CHOLEDOLITHIASIS,


    CHOLELITHIASIS

    PREDISPOSING Female
    Hemolysis
    FACTORS:

    (5 F’s) Forty

    Hemoglobin
    Fertile:
    (multigravida; use
    of OCP)
    Decrease bile acid
    Bilirubin synthesis in the liver
    Fair (Caucasian)

    Increase cholesterol Fat (obese)


    synthesis in the liver
    CA bilirubinate/
    Calcified bilirubin

    Bile supersaturated with


    cholesterol

    Gallstone Bile stone


    s

    Bile flow Irritation of the gall bladder


    CHOLELITHIASIS
    obstruction (inflammation)

    BILE STASIS
    > Biliary colic
    CHOLECYSTITIS
    > N&V

    > Murphy’s sign >RUQ pain that may


    radiate to midsternal/
    > Jaundice
    right shoulder

    >N&V

    >Fever

    You might also like