RENAL FAILURE

RAAS MULFUNCTION Decrease Capacity of the Retention of Nitrogenous Waste Inability of the Kidney to
kidney to excrete produce erythropoietin
potassium
Na and Water Retention AZOTEMIA Increase BUN,
Decrease RBC production
Creatinine in the
in the Bone Marrow
HYPERKALEMIA blood
Decrease Increase Blood EDEMA Deposits of Urea
Urine Output Volume Crystals on the Skin
(HYPERVOLEMIA)
ANEMIA
Muscle Wasting,
Weakness Pruritus and Uremic Frost
Decrease circulating O2 in the
HYPERTENSI body
ON

Continuous decline in Renal Fatigue, Body Weakness

Function

GSTAGE IV

End Stage Renal Failure

GFR <15 mL/min/1.73 m2

Continuous Multisystem Affectation

Multiple Organ Failure

DEATH