Garland Science

catalog 2011

www.garlandscience.com
new titles and bestsellers

Fourth Edition
Microbiology
Human Molecular Genetics A Clinical Approach
Tom Strachan and Andrew Read Anthony Strelkauskas, Jennifer Strelkauskas, and Danielle
Human Molecular Genetics is an established and class-proven Moszyk-Strelkauskas
textbook for upper-level undergraduates and graduate Microbiology: A Clinical Approach is a new and unique
students, which provides an authoritative and integrated microbiology textbook for health science students studying
approach to the molecular aspects of human genetics. See microbiology. It is clinically-relevant and uses the theme of
page 6 infection as its foundation. See page 9

Fourth Edition Living in a Microbial World

BIOS Instant Notes in Biochemistry Bruce Hofkin
David Hames and Nigel Hooper Living in a Microbial World is a textbook written for students
taking a general microbiology or microbiology-themed course
BIOS Instant Notes in Biochemistry presents the essential
for non-science majors. It teaches the essential concepts of
facts of biochemistry with detailed explanations and clear
microbiology through practical examples and a conversational
illustrations, enabling the reader to grasp the subject quickly and
writing style intended to make the material accessible to a wide
easily. The Fourth Edition has been updated to include changes
audience. See page 10
in terminology and revised and expanded sections on protein
structure, protein function, studying proteins, and PCR-related
technology. See page 2

Second Edition Fields, Forces, and Flows in

Molecular Driving Forces
Statistical Thermodynamics in Biology, Chemistry,
Physics and Nanoscience
Ken A. Dill, and Sarina Bromberg
Molecular Driving Forces, Second Edition is an introductory
statistical thermodynamics text that describes the principles
and forces that drive chemical and biological processes. It
demonstrates how the complex behaviors of molecules can
result from a few simple physical processes, and how simple
models provide surprisingly accurate insights into the workings
of the molecular world. See page 3
Biological Systems
Alan J Grodzinsky
Fields, Forces, and Flows in Biological Systems describes the
fundamental driving forces for mass transport, electric current,
and fluid flow as they apply to the biology and biophysics of
molecules, cells, tissues, and organs. Basic mathematical and
engineering tools are presented in the context of biology and
physiology. See page 14

Third Edition Third Edition

Essential Cell Biology
Bruce Alberts, Dennis Bray, Karen Hopkin, Alexander Johnson,
Julian Lewis, Martin Raff, Keith Roberts, and Peter Walter
Essential Cell Biology provides an accessible introduction to
the fundamental concepts of cell biology. It has a proven track
record in providing readers with a conceptual and accessible
grounding in cell biology. See page 1
The Immune System
Peter Parham
The Immune System, Third Edition has been designed for use
in immunology courses for undergraduate, medical, dental,
and pharmacy students. This class-tested and successful
textbook synthesizes the established facts of immunology into
a comprehensible, coherent, and up-to-date account of how
the human immune system works. See page 13

Fifth Edition Eighth Edition

Molecular Biology of the Cell Janeway’s Immunobiology
Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff,
NEW EDITION
Kenneth M. Murphy
Keith Roberts, and Peter Walter FORTHCOMING
Janeway’s Immunobiology is an introductory text for
For nearly a quarter century, Molecular Biology of the Cell has use in immunology courses for undergraduates, graduate
been the leading cell biology textbook. This tradition continues students, and medical students. The Eighth Edition has been
with the new Fifth Edition, which has been completely revised comprehensively updated throughout. See page 12
and updated to describe our current, rapidly advancing
understanding of cell biology. See page 1

contents For more information on the books in this

catalog, please contact:
Cell and Molecular Biology . . . . . . . . 1 Chemistry . . . . . . . . . . . . . . . . . . . . . 19 Lucy Brodie
Genetics . . . . . . . . . . . . . . . . . . . . . . . 6 General Biology . . . . . . . . . . . . . . . . 21 Senior Marketing Manager
Microbiology . . . . . . . . . . . . . . . . . . . 9 BIOS Instant Notes Series . . . . . . . . 22 lucy.brodie@tandf.co.uk
Immunology . . . . . . . . . . . . . . . . . . . . 12 The Basics, Advanced Methods and Alexander Cavell
Structural Biology . . . . . . . . . . . . . . . . 14 Advanced Text series. . . . . . . . . . . . . . 23 Textbook Marketing Coordinator
Computational Biology . . . . . . . . . . . 16 Title Index . . . . . . . . . . . . . . . . . . . . . 24 alexander.cavell@tandf.co.uk
Plant Science . . . . . . . . . . . . . . . . . . . 18 Author Index . . . . . . . Inside Back cover Dominique Spindler
Order Form . . . . . . . . . . . . Center Page Marketing Assistant
dominique.spindler@tandf.co.uk

Third Edition
Essential Cell Biology
Bruce Alberts, University of California, San Francisco, USA, Dennis Bray,
University of Cambridge, UK, Karen Hopkin, Science Journalist and Biochemist,
USA, Alexander Johnson, University of California, San Francisco, USA,
Julian Lewis, Cancer Research UK, Martin Raff, University College London, UK,
Keith Roberts, Emeritus, John Innes Centre, UK, and Peter Walter, University of
California, San Francisco, USA
‘’For cell and molecular biologists, this series of
books has become the absolute reference bible
both in the laboratory and in the classroom.
Previous editions have demonstrated how well
authors and editors amalgamated, condensed,
and summarized the huge area of cell biology
into readily accessible bytes of information.  This
third edition does not deviate from this ethic and
enthralls the reader with a mind-boggling 731
pages of essential cell biology.
The Biochemist
Essential Cell Biology provides an accessible introduction to the fundamental
concepts of cell biology. Its lively writing and exceptional illustrations make it the
ideal textbook for a first course in cell and molecular biology. The text and figures
are easy-to-follow, accurate, clear, and engaging for the introductory student.
Molecular detail has been kept to a minimum in order to provide the reader with
a cohesive, conceptual framework of the basic science that underlies our current
understanding of biology.
The Third Edition is thoroughly updated scientifically, yet maintains the academic
level and size of the previous edition. The book is accompanied by a Media
DVD-ROM with over 130 animations and videos, all the figures from the book,
and a new self-test quizzing feature for students.
Contents:
1. Introduction to Cells 2. Chemical Components of Cells 3. Energy, Catalysis,
and Biosynthesis 4. Protein Structure and Function 5. DNA and Chromosomes 6.
DNA Replication, Repair, and Recombination 7. From DNA to Protein: How Cells
Read the Genome 8. Control of Gene Expression 9. How Genes and Genomes
Evolve 10. Manipulating Genes and Cells 11. Membrane Structure 12. Mem-
brane Transport 13. How Cells Obtain Energy from Food 14. Energy Generation
in Mitochondria and Chloroplasts 15. Intracellular Compartments and Transport
16. Cell Communication 17. Cytoskeleton 18. The Cell Division Cycle 19. Genetics,
Meiosis, and the Molecular Basis of Heredity 20. Tissues and Cancer
Garland Science
April 2009: 860pp: 850 illus
Hb: 978-0-8153-4129-1: £96.00
Pb: 978-0-8153-4130-7: £50.00
Media DVD-ROM contains:
- Essential Cell Biology Interactive Media Player with over 130 movies.
- Student self-quizzes.
- Movie Vault, an archive of movies in Quicktime®, MPEG, and iPod® formats.
- PowerPoint® presentations of book figures.
- JPEG archive of book figures.
Classwire™ includes:
- Free online course management tools (www.classwire.com/garlandscience).
- PowerPoint® presentations of book figures.
- JPEG archive of book figures.
- Over 130 movies.
- Question Bank for instructors.
- Lecture Outlines with figures integrated in PowerPoint®.
Classwire is a trademark of Chalkfree, Inc.
@ E-mail: garlanduk@tandf.co.uk
for more information
@GarlandScience
Cell and Molecular Biology 1
Fifth Edition
Molecular Biology of the Cell
Bruce Alberts, University of California, San Francisco, USA, Alexander Johnson,
University of California, San Francisco, USA, Julian Lewis, Cancer Research UK,
UK, Martin Raff, University College London, UK, Keith Roberts, Emeritus, John
Innes Centre, UK, and Peter Walter, University of California, San Francisco, USA
‘Professors, lecturers, and instructors will find the
fifth edition of the book Molecular Biology of the
Cell and its accompanying Problems Book to be an
excellent choice for guiding their students through
the maze of the cell’s molecular structures and
biochemical processes.’
The Quarterly Review of Biology
For nearly a quarter century Molecular Biology of the Cell
has been the leading cell biology textbook. This tradition
continues with the new Fifth Edition, which has been completely revised and
updated to describe our current, rapidly advancing understanding of cell biol-
ogy. To list but a few examples, a large amount of new material is presented on
epigenetics; stem cells; RNAi; comparative genomics; the latest cancer therapies;
apoptosis (now its own separate chapter); and cell cycle control and the mechanics
of M phase (now integrated into one chapter). The hallmark features of Molecular
Biology of the Cell have been retained, such as its consistent and comprehensive
art program, clear concept headings, and succinct section summaries. Addition-
ally, in response to extensive feedback from readers, the Fifth Edition now includes
several new features.
The Media DVD-ROM holds the multicellular systems chapters (21-25) of the text
as well. By skillfully extracting the fundamental concepts from this enormous and
ever-growing field, the authors tell the story of cell biology, and thereby create a
coherent framework through which readers may approach and enjoy this subject
that is so central to all of biology. There is also a reference edition of Molecular
Biology of the Cell, Fifth Edition (ISBN 978-0-8153-4111-6) that contains Chap-
ters 1-25 entirely in printed format.
Contents:
PART I INTRODUCTION TO THE CELL
1. Cells and Genomes 2. Cell Chemistry and Biosynthesis 3. Proteins
PART II BASIC GENETIC MECHANISMS
4. DNA, Chromosomes, and Genomes 5. DNA Replication, Repair, and Recombination
6. How Cells Read the Genome: From DNA to Protein 7. Control of Gene Expression
PART III METHODS
8. Manipulating Proteins, DNA, and RNA 9. Visualizing Cells
PART IV INTERNAL ORGANIZATION OF THE CELL
10. Membrane Structure 11. Membrane Transport of Small Molecules and the
Electrical Properties of Membranes 12. Intracellular Compartments and Protein
Sorting 13. Intracellular Vesicular Traffic 14. Energy Conversion:Mitochondria and
Chloroplasts 15. Mechanisms of Cell Communication 16. The Cytoskeleton 17.
The Cell Cycle 18. Apoptosis
PART V CELLS IN THEIR SOCIAL CONTEXT
19. Cell Junctions, Cell Adhesion, and the Extracellular Matrix 20. Cancer Chap-
ters 21–25 available on Media DVD-ROM: 21. Sexual Reproduction: Meiosis,
Germ Cells, and Fertilization 22. Development of Multicellular Organisms 23.
Specialized Tissues, Stem Cells, and Tissue Renewal 24. Pathogens, Infection, and
Innate Immunity 25. The Adaptive Immune System
Garland Science
January 2008: 1,392pp: 1,526 illus
Hb: 978-0-8153-4105-5: £115.00
Pb: 978-0-8153-4106-2: £61.00
Transparency Set: 978-0-8153-4109-3: £408.00
Media DVD-ROM contains :
- Cell Biology Interactive Media Player with over 130 movies.
- PowerPoint® presentations of book figures.
- JPEG archive of book figures.
- Chapters 21-25: Multicellular Systems.
Classwire™ includes:
- Free online course management tools (www.classwire.com/garlandscience).
- PowerPoint® presentations of book figures.
- JPEG archive of book figures.
- Over 130 movies.
- Test Questions for instructors.
- Lecture Outlines in PowerPoint®.
8 E-bookstore: www.ebookstore.tandf.co.uk
eBooks are only available to order online
 2 Cell and Molecular Biology
Fifth Edition
Molecular Biology of the Cell
Reference Edition
Bruce Alberts, University of California, San Francisco, USA, Alexander Johnson,
University of California, San Francisco, USA, Julian Lewis, Cancer Research UK,
UK, Martin Raff, University College London, UK, Keith Roberts, Emeritus, John
Innes Centre, UK, and Peter Walter, University of California, San Francisco, USA
Ideal for libraries, laboratories, and researchers, this Reference Edition of
Molecular Biology of the Cell, Fifth Edition offers an alternative to the student
version by providing the complete text of Chapters 1-25 in printed format. The
Reference Edition is also packaged with the Molecular Biology of the Cell, Fifth
Edition Media DVD-ROM.
Garland Science
January 2008: 1,728pp: 1,891 illus
Hb: 978-0-8153-4111-6: £130.00
Fifth Edition
Molecular Biology of the Cell
The Problems Book
John Wilson, Baylor College of Medicine, USA, and Tim Hunt, Cancer Research,
UK
The Problems Book helps students appreciate the ways
in which experiments and simple calculations can lead
to an understanding of how cells work by introducing
the experimental foundation of cell and molecular
biology. Each chapter will review key terms, test for
understanding basic concepts, and pose research-
based problems. The Problems Book has been de-
signed to correspond with the first twenty chapters of
Molecular Biology of the Cell, Fifth Edition.
• Includes the solutions to the end-of-chapter problems in the textbook
Molecular Biology of the Cell, Fifth Edition.
• Contains over 2,000 problems and their solutions.
• All of the solutions to the problems in The Problems Book are on the CD-ROM
that is packaged with every copy of the book.
• The problems are organized into the following categories: Terms to Learn, SERIES FEATURES
Definitions, True/False, Thought Problems, Calculations, and Data Handling.
The Problems Book will be useful for homework assignments and as a basis for
class discussion. It could even provide inspiration for exam questions.
Contents:
1. Cells and Genomes 2. Cell Chemistry and Biosynthesis 3. Proteins 4. DNA,
Chromosomes, and Genomes 5. DNA Replication, Repair and Recombination 6.
How Cells Read the Genome: From DNA to Protein 7. Control of Gene Expres-
sion 8. Manipulating Proteins, DNA and RNA 9. Visualizing Cells – NEW TO THIS
EDITION 10. Membrane Structure 11. Membrane Transport of Small Molecules
and the Electrical Properties of Membranes 12. Intracellular Compartments
and Protein Sorting 13. Intracellular Vesicular Transport 14. Energy Conversion:
Mitochondria and Chloroplasts 15. Mechanisms of Cell Communication 16. The
Cytoskeleton 17. The Cell Cycle 18. Apoptosis 19. Cell Junctions, Cell Adhesion,
and the Extracellular Matrix – NEW TO THIS EDITION 20. Cancer – NEW TO THIS
EDITION • Glossary • Index • Tables
Garland Science
January 2008: 608pp: 826 illus
Pb: 978-0-8153-4110-9: £26.00
ORDER NOW!
See Order Form in the
center of this catalog ' Phone: +44 (0)1235 400524
New Fourth Edition
BIOS Instant Notes in Biochemistry
David Hames and Nigel Hooper, both at University of Leeds, UK
SERIES FEATURES
• Affordably priced.
• Contains all of the essential facts that a student needs
to know in a concise book–accessible, easy to read,
approachable.
• Excellent for review ahead of examinations.
BIOS Instant Notes in Biochemistry, Fourth Edition, is a
concise biochemistry textbook for undergraduates.  All
of the important areas of biochemistry are covered in a
format that is ideal for learning and rapid revision.  Each
topic begins with a summary of the essential facts – an ideal revision checklist
– followed by a description of the subject that focuses on the core information,
with clear, simple diagrams that are easy for students to understand and recall in
essays and examinations.
BIOS Instant Notes in Biochemistry, Fourth Edition, is fully up-to-date and
covers:
• Cells • Amino acids and proteins • Studying proteins • Enzymes • Membranes
and cell signaling • DNA structure and replication • RNA synthesis and processing
• Protein synthesis • Recombinant DNA technology • Carbohydrate metabolism
• Lipid metabolism • Respiration and energy • Nitrogen metabolism
BIOS Instant Notes
Taylor & Francis
March 2011: 467pp: 297 illustrations
Pb: 978-0-415-60845-9: £20.00
E-book available at www.ebookstore.tandf.co.uk
SUPPLEMENT:
Artwork available at www.garlandscience.com.
New Third Edition
BIOS Instant Notes in Neuroscience
Alan Longstaff, Science Writer and Neuroscience Lecturer, UK
• Affordably priced.
• Contains all of the essential facts that a student needs
to know in a concise book–accessible, easy to read,
approachable.
• Excellent for review ahead of examinations.
BIOS Instant Notes in Neuroscience, Third Edition, is a
concise neuroscience textbook for undergraduates. All
of the important areas of neuroscience are covered in a
format that is ideal for learning and rapid revision. Each
topic begins with a summary of the essential facts – an ideal revision checklist
– followed by a description of the subject that focuses on the core information,
with clear simple diagrams that are easy for students to understand and recall in
essays and examinations.
BIOS Instant Notes in Neuroscience, Third Edition, is fully up-to-date and covers:
• Organization of the nervous system • Neuron excitation • Synapses • Neu-
rotransmitters • Elements of neural computing • Somatosensory systems •
Vision • Hearing • Smell and taste • Motor function: spinal cord and brainstem
• Movement: cortex, cerebellum and basal ganglia • Neuroendocrinology and
autonomic functions • Brain and behaviour • Learning and Memory • Neuro-
science methods
BIOS Instant Notes
Taylor & Francis
March 2011: 400pp: 228 illustrations
Pb: 978-0-415-60769-8: £20.00
E-book available at www.ebookstore.tandf.co.uk
SUPPLEMENT:
Artwork available at www.garlandscience.com.
Garland Science
8 Website: www.garlandscience.com

New Second Edition
Molecular Driving Forces
Statistical Thermodynamics in Biology, Chemistry, Physics and
Nanoscience
Ken A. Dill, Stony Brook University, USA, and Sarina Bromberg, Pescadero,
California, USA
Molecular Driving Forces, Second Edition is an intro-
ductory statistical thermodynamics text that describes
the principles and forces that drive chemical and
biological processes. It demonstrates how the complex
behaviors of molecules can result from a few simple
physical processes, and how simple models provide
surprisingly accurate insights into the workings of the
molecular world.
Widely adopted in its First Edition, Molecular Driving
Forces is regarded by teachers and students as an ac-
cessible textbook that illuminates underlying principles
and concepts. The Second Edition includes two brand new chapters: (1) “Micro-
scopic Dynamics” introduces single molecule experiments; and (2) “Molecular
Machines” considers how nanoscale machines and engines work. “The Logic of
Thermodynamics” has been expanded to its own chapter and now covers heat,
work, processes, pathways, and cycles. New practical applications, examples,
and end-of-chapter questions are integrated throughout the revised and up-
dated text, exploring topics in biology, environmental and energy science, and
nanotechnology. Written in a clear and reader-friendly style, the book provides
an excellent introduction to the subject for novices while remaining a valuable
resource for experts.
Key Features
• Writing is readable, friendly, and accessible.
• Carefully crafted figures streamline complex data to promote conceptual
understanding.
• Simple models, such as lattice models, encapsulate complex processes.
• Selection of topics prepares students for an interdisciplinary world—in
chemistry, biology, physics, material science, environmental science, and
nanoscience.
• Includes the most extensive and modern applications of current physical
chemistry books.
• Worked examples in chapters explain key concepts and show their practical
application.
• Contains all the math and physics needed for students.
• Appropriate as a physical chemistry book at several levels, from undergradu-
ate chemistry or bioengineering to graduate physics and biophysics.
• Each chapter contains end-of-chapter problem sets, references, and sugges-
tions for further reading.
New in the Second Edition
• A new chapter on “Microscopic Dynamics” introduces nonequilibrium sta-
tistical mechanics, including the dynamics of single-molecule or few-particle
systems.
• Another chapter explores the principles of molecular machines: how ATP
drives proton pumps and molecular motors, and how signals and information
are transduced in biology, for example.
• “The Logic of Thermodynamics” has been expanded and moved to its own
chapter.
• A section has been added on how batteries and fuel cells work.
• Purely mathematical topics are moved to the appendix.
• New applications, worked examples, and end-of-chapter problems, keep the
book fresh and relevant.
Contents:
1. Principles of Probability 2. Extremum Principles Predict Equilibria 3. Heat,
Work & Energy 4. Math Tools: Multivariate Calculus 5. Entropy & the Boltzmann
Law 6. Thermodynamic Driving Forces 7. The Logic of Thermodynamics 8.
Laboratory Conditions & Free Energies 9. Maxwell’s Relations & Mixtures 10. The
Boltzman Distribution Law 11. The Statistical Mechanics of Simple Gases & Solids
12. What Is Temperature? What Is Heat Capacity? 13. Chemical Equilibria 14.
Equilibria Between Liquids, Solids, & Gases 15. Solutions & Mixtures 16. The Sol-
vation & Transfer of Molecules Between Phases 17. Physical Kinetics: Diffusion,
Permeation & Flow 18. Microscopic Dynamics 19. Chemical Kinetics & Transition
States 20. Coulomb’s Law of Electrostatic Forces 21. The Electrostatic Potential
22. Electrochemical Equilibria 23. Salt Ions Shield Charged Objects in Solution
com
@ E-mail: garlanduk@tandf.co.uk
for more information
@GarlandScience
Cell and Molecular Biology 3
24. Intermolecular Interactions 25. Phase Transitions 26. Cooperativity: The
Hexlix-Coil, Isling & Landau Models 27. Adsorption, Binding & Catalysis 28. Multi-
site & Cooperative Ligand Binding 29. Bio & Nano Machines 30. Water 31. Water
as a Solvent 32. Polymer Solutions 33. Polymer Elasticity & Collapse 34. Polymers
Resist Confinement & Deformation • Appendices
Garland Science
January 2011: 720pp: 690 illus
Pb: 978-0-8153-4430-8: £49.00
SUPPLEMENTS:
Artwork and Solutions Manual available to adopting instructors upon request at
science@garland.com
Cellular Signal Processing
An Introduction to the Molecular Mechanisms of Signal Transduction
Friedrich Marks, Ursula Klingmüller and Karin Müller-Decker, all at University of
Heidelberg and the German Cancer Research Center, Germany
‘This book provides comprehensive coverage of
signal transduction. Unlike other texts currently
available, a common theme of data processing
by cellular machinery runs through this book
which makes it stand out favorably against the
competition. Material is up-to-date and covers
the areas that are at the forefront of cell signal-
ing research today.’ Alexey Veraksa, University of
Massachusetts, Boston, USA
Cellular Signal Processing is intended for use in signal transduction courses for
undergraduate and graduate students. It offers a unifying view of cell signaling
that is based on the concept of protein interactions acting as sophisticated data
processing networks that govern intracellular and extracellular communica-
tion. The content is guided by three major principles that are central to signal
transduction: the protein network, its energy supply, and its evolution. It includes
coverage of all important aspects of cell signaling, ranging from prokaryotic
signal transduction to neuronal signaling. It also highlights the clinical aspects of
cell signaling in health and disease.
Contents:
1. The “Brain of the Cell”: Data Processing by Protein Networks 2. Supplying the
Network with Energy: Basic Biochemistry of Signal Transduction 3. Evolution of
Cellular Data Processing 4. Basic Equipment: G-Proteins, Second Messengers, and
Protein Kinases 5. Signal Transduction by Receptors with Seven Transmembrane
Domains 6. Signal Transduction by Serine/Threonine Kinase-Coupled Receptors
7. Signal Transduction by Tyrosine Kinase- and Protein Phosphatase-Coupled
Receptors: A Late Invention of Evolution 8. Gene Transcription: The Ultimate
Target of Signal Transduction 9. Signals Controlling mRNA Translation 10. Signal
Transduction by Small G-proteins: The Art of Molecular Targeting 11. Mitogen-
activated Protein Kinase and Nuclear Factor kB Modules 12. Cancer and Regula-
tion of Cell Division 13. Signal Transduction by Proteolysis and Programmed Cell
Death 14. Signal Transduction by Ions 15. Sensory Signal Processing 16. Signaling
at Synapses: Neurotransmitters and Their Receptors 17. Putting Together the
Pieces: The Approach of Systems Biology
Garland Science
January 2009: 656pp: 428 illus
Pb: 978-0-8153-4215-1: £44.00
SUPPLEMENT:
Artwork available at www.garlandscience.com.
8 E-bookstore: www.ebookstore.tandf.co.uk
eBooks are only available to order online
 4 Cell and Molecular Biology
Physical Biology of the Cell
Rob Phillips, California Institute of Technology, USA, Jane Kondev, Brandeis
University, USA, and Julie Theriot, Stanford University, USA
‘…[The] authors of Physical Biology of the Cell
have produced one of the first multi-purpose text-
books that is readily accessible to both physicists
and biologists…. When read from cover to cover,
the book is both very instructive and highly enter-
taining with the authors using humour to deliver
strong take-home messages in each chapter….
Physical Biology of the Cell provides instructors
with excellent material to create a graduate level
course in biology or physics. The book is also very timely as it presents
the most recent views in cell biology.’ Nature Cell Biology
Physical Biology of the Cell is a biophysics textbook that explores how the
basic tools and insights of physics and mathematics can illuminate the study of
molecular and cell biology. Drawing on key examples and seminal experiments
from cell biology, the book demonstrates how quantitative models can help
refine our understanding of existing biological data and also be used to make
useful predictions. The book blends traditional models in cell biology with the
quantitative approach typical in physics, in order to introduce the reader to both
the possibilities and boundaries of the emerging field of physical biology. While
teaching physical model building in cell biology through a practical, case-study
approach, the text explores how quantitative modeling can be used to build a
more profound, intuitive understanding of cell biology.
Contents:
Part I The Facts of Life
1. Why: Biology By the Numbers 2. What and Where: Construction Plans for Cells
and Organisms 3. When: Stopwatches at Many Scales 4. Who: “Bless the Little
Beasties”
Part II Life at Rest
5. Mechanical and Chemical Equilibrium in the Living Cell 6. Entropy Rules! 7.
Two-State Systems: From Ion Channels to Cooperative Binding 8. Random Walks
and the Structure of Macromolecules 9. Electrostatics for Salty Solutions 10.
Beam Theory: Architecture for Cells and Skeletons 11. Biological Membranes: Life
in Two Dimensions
Part III Life in Motion
12. The Mathematics of Water 13. A Statistical View of Biological Dynamics 14.
Life in Crowded and Disordered Environments 15. Rate Equations and Dynamics
in the Cell 16. Dynamics of Molecular Motors 17. Biological Electricity and the
Hodgkin-Huxley Model
Part IV The Meaning of Life
18. Sequences, Specificity and Evolution 19. Network Organization in Space and
Time 20. Whither Physical Biology
Garland Science
December 2008: 800pp: 550 illus, 25 tables
Pb: 978-0-8153-4163-5: £50.00
SUPPLEMENTS:
The following supplements are available for instructors and students:
• PowerPoint® slides of the figures & micrographs.
• “Hints for the reader” for some of the more difficult problems.
• Supplementary data sets.
• Supplementary videos.
• Solutions Manual for all end-of-chapter problems.
With the exception of the Solutions Manual, these resources are available at
www.garlandscience.com/pboc.
The Solutions Manual, which is available only to qualified instructors,
may be requested via e-mail from science@garland.com.
ORDER NOW!
See Order Form in the
center of this catalog ' Phone: +44 (0)1235 400524
Second Edition
Cell Movements
From Molecules to Motility
Dennis Bray, University of Cambridge, UK
Cell Movements vividly describes how complex move-
ments can arise from the properties and behaviors of
biological molecules. This second edition is updated
throughout with recent advances in the field and has a
completely revised and redrawn artwork program. The
text is suitable for advanced undergraduates as well as
for professionals wishing for an overview of this field.
contents:
1. Cell Swimming 2. Migration of Cells over Surfaces 3.
Cell Behavior 4. The Cytoskeleton 5. Actin Filaments 6.
Actin and Membranes 7. Myosin 8. Firoblast Locomo-
tion 9. The Molecular Basis of Muscle Contraction 10. Muscle Development 11.
Microtubules 12. Organelle Transport 13. Mitosis 14. Cilia 15. Centrioles and
Basal Bodies 16. Bacterial Movements 17. Intermediate Filaments 18. Cell Me-
chanics 19. Cell Shape 20. Cell Movements and Embyogenesis
Garland Science
2000: 392pp
Pb: 978-0-8153-3282-4: £51.00
Mathematics for Biological Scientists
Mike Aitken, Bill Broadhurst, and Stephen Hladky, all at the University of
Cambridge, UK
Mathematics for Biological Scientists is a new un-
dergraduate textbook which covers the mathematics
necessary for biology students to understand, interpret
and discuss biological questions.
The book’s twelve chapters are organized into four
themes. The first theme covers the basic concepts of
mathematics in biology, discussing the mathematics
used in biological quantities, processes and structures.
The second theme, calculus, extends the language of
mathematics to describe change. The third theme is
probability and statistics, where the uncertainty and
variation encountered in real biological data is described. The fourth theme is
explored briefly in the final chapter of the book, which is to show how the ‘tools’
developed in the first few chapters are used within biology to develop models of
biological processes.
Mathematics for Biological Scientists fully integrates mathematics and biology
with the use of color illustrations and photographs to provide an engaging and
informative approach to the subject of mathematics and statistics within
biological science.
Contents:
1. Quantities and Units 2. Numbers and Equations 3. Tables, Graphs, and Func-
tions 4. Shapes, Waves, and Trigonometry 5. Differentiation 6. Integration 7.
Calculus: Expanding the Toolkit 8. The Calculus of Growth and Decay Processes
9. Descriptive Statistics and Data Display 10. Probability 11. Statistical Infer-
ence 12. Biological Modeling, Presenting Your Work, End of Chapter Questions,
Answers to End of Chapter Questions
Garland Science
October 2009: 482pp: 25 illus, 2 halftones, 175 line drawings
Pb: 978-0-8153-4136-9: £33.00
SUPPLEMENT:
Artwork available at www.garlandscience.com.
Garland Science
8 Website: www.garlandscience.com
 Cell and Molecular Biology 5

The Biology of Cancer

Robert A. Weinberg, Whitehead Institute for Biomedical Research, MIT, USA
‘The Biology of Cancer is no doubt the defini-
tive statement on its topic today.’ Science
‘There is no comparable text in cancer biology
and no single book that is so current and infor-
mative.’ Nature
The Biology of Cancer is a textbook for undergradu-
ate and graduate biology students as well as medical
students studying the molecular and cellular bases
of cancer. The book presents the principles of cancer
biology in an organized, cogent, and in-depth manner.
The clarity of writing and the lucid full-color art program make the book acces-
sible and engaging. The information unfolds through the presentation of key ex-
periments which give readers a sense of discovery and provides insights into the
conceptual foundation underlying modern cancer biology. The Biology of Cancer
synthesizes the findings of three decades of recent cancer research and proposes
a conceptual framework from which to teach about these discoveries.
It provides the necessary structure, organization, and content for a course on
cancer biology for advanced undergraduates and beginning doctoral students.
The book is comprehensive and offers many pedagogical features to assist teach-
ing and learning. The book includes many recent and topical references, and is
intended to empower the student to move directly into the primary research
literature. The text is up-to-date and provides current information on topics such
as tumor stem cells and recently introduced chemotherapeutics. State-of-the-art
techniques are discussed throughout. Modern biomedical research is explored,
helping readers to hone their analytical abilities and to assimilate and think clear-
ly about complex biological processes. The Biology of Cancer provides insights
into many aspects of immunology, developmental biology, and neurobiology.
The exceptional full-color art program contains many images published for the
first time. The book is extensively illustrated with schematic drawings, micro-
graphs, computer-generated models and graphs. The pieces were chosen to
support and clarify the concepts, as well as to supply additional interest.
Besides its value as a textbook, The Biology of Cancer will be a useful reference
for individuals working in biomedical laboratories, and for clinical professionals.

Contents:
1. The Biology and Genetics of Cells and Organisms 2. The Nature of Cancer
3. Tumor Viruses 4. Cellular Oncogenes 5. Growth Factors and their Receptors
6. Cytoplasmic Signaling Circuitry Programs Many of the Traits of Cancer
7. Tumor Suppressor Genes 8. pRb and Control of the Cell Cycle Clock 9. p53
and Apoptosis: Master Guardian and Executioner 10. Eternal Life: Cell Immor-
talization and Tumorigenesis 11. Multistep Tumorigenesis 12. Maintenance of
Genomic Integrity and the Development of Cancer 13. Dialogue Replaces Mono-
logue: Heterotypic Interactions and the Biology of Angiogenesis 14. Moving Out:
Invasion and Metastasis 15. Crowd Control: Tumor Immunology and Immuno-
therapy 16. The Rational Treatment of Cancer
Garland Science
2006: 864pp: 800 illus
Hb: 978-0-8153-4078-2: £100.00
Pb: 978-0-8153-4076-8: £50.00
Packaged with a CD-ROM and a Poster
SUPPLEMENTS:
l All of the book figures provided as PowerPoint® slides and in JPEG format.
l A select number of animations, molecular models, and videos.
l Mini-lecture audio files.
l Classwire (course management system and library of teaching resources)
www.classwire.com/garlandscience

com
@ E-mail: garlanduk@tandf.co.uk
for more information
@GarlandScience
8 E-bookstore: www.ebookstore.tandf.co.uk
eBooks are only available to order online
 6 genetics
New Fourth Edition
Human Molecular Genetics
Tom Strachan, Newcastle University, UK, and Andrew Read, University of
Manchester, UK
Praise for previous editions:
‘This book is an excellent companion for stu-
dents in human genetics or for researchers that
want to gain background and knowledge in this
field.’ Human Genetics Journal
‘…addresses the gap between introductory
textbooks and the primary literature. There’s no
other textbook quite like it.’ Nature
Human Molecular Genetics is an established and class-proven textbook for
upper-levelundergraduates and graduate students which provides an authori-
tative and integrated approach to the molecular aspects of human genetics.
While maintaining the hallmark features of previous editions, the Fourth Edition
includes new Key Concepts at the beginning of each chapter and annotated
Further Reading at the conclusion of each chapter, to help readers navigate the
wealth of information in this subject.
Human Molecular Genetics has been restructured so that discussion of genomic
technologies is integrated into the text. A new section that concentrates on ge-
netic testing, screening, and disease models has been added. Coverage of stem
cells, cell immortalization, studying gene function and structure, comparative
genomics, model organisms, and epigenetics has been expanded.
The revised and updated Fourth Edition of Human Molecular Genetics bridges
the gap between introductory textbooks and research papers, emphasizing
underlying concepts and principles throughout.
CONTENTS:
1. Nucleic Acid Structure and Gene Expression 2. Chromosome Structure and
Function 3. Genes in Pedigrees and Populations 4. Cells and Cell-Cell Communi-
cation 5. Principles of Development 6. Amplifying DNA: Cell-based DNA Cloning
and PCR 7. Nucleic Acid Hybridization: Principles and Applications 8. Analyzing
the Structure and Expression of Genes and Genomes 9. Organization of the
Human Genome 10. Model Organisms, Comparative Genomics and Evolution
11. Human Gene Expression 12. Studying Gene Function in the Post-Genome
Era 13. Human Genetic Variability and its Consequences 14. Genetic Mapping of
Mendelian Characters 15. Mapping Genes Conferring Susceptibility to Complex
Disease 16. Identifying Human Disease Genes and Susceptibility Factors 17. Can-
cer Genetics 18. Genetic Testing of Individuals 19. Pharmacogenetics, Personal-
ized Medicine, and Population Screening 20. Genetic Manipulation of Animals
for Modeling Disease and Investigating Gene Function 21. Genetic Approaches to
Treating Disease
Garland Science
April 2010: 800pp: 135 tables, 80 halftones, 500 line drawings
Pb: 978-0-8153-4149-9: £49.00
supplement:
Artwork available on Classwire at www.classwire.com/garlandscience.
New
Introduction To Genetics: A Molecular Approach
T A Brown, University of Manchester, UK
The textbook presents transmission genetics by first explaining molecular struc-
tures and mechanisms before introducing the more challenging concepts and
terminology associated with the subject. By taking this modern and innovative
approach, the book will work well in courses that emphasize the molecular as-
pects of genetics. The text addresses the vital role of genetics in the world today,
from agriculture and industry to medicine and forensics. Discrete “Research
Briefing” sections throughout the text introduce the experimental basis of genet-
ics without interrupting the flow of the main narrative. Extensive questions are
at the end of each chapter to help students test their knowledge of the material.
Instructor supplements include the book’s art program in PowerPoint and JPEG
formats, a question bank, and lecture outline slides which will save you time
while preparing lectures and exams. The Introduction to Genetics student com-
panion website contains animations with voiceover narration to help students
visualize difficult-to-understand molecular interactions.
ORDER NOW!
See Order Form in the
center of this catalog ' Phone: +44 (0)1235 400524
CONTENTS:
PART 1 - GENES AS UNITS OF BIOLOGICAL INFORMATION
1. The scope of modern genetics 2. DNA 3. Genes 4. Transcription of DNA to RNA
5. Types of RNA molecule: messenger RNA 6. Types of RNA molecule: noncoding
RNA 7. The genetic code 8. Protein synthesis 9. Control of gene expression
PART 2 - GENES AS UNITS OF INHERITANCE
10. DNA replication 11. Inheritance of genes during eukaryotic cell division 12.
Inheritance of genes in bacteria 13. Inheritance of genes during virus infection
cycles 14. Inheritance of DNA molecules during eukaryotic sexual reproduction
15. Inheritance of genes during eukaryotic sexual reproduction 16. Mutation and
DNA repair 17. Inheritance of genes in populations
PART 3 - GENETICS IN OUR MODERN WORLD
18. Genes in differentiation and development 19. The human genome 20. Genes
and medicine 21. DNA in forensics and studies of human history 22. Genes in
industry and agriculture 23. The ethical issues raised by modern genetics
Garland Science
October 2011: 660pp: 1,398 illustrations
Pb: 978-0-8153-6509-9: £46.00
SUPPLEMENTS:
Artwork, question bank, and lecture slides available on www.garlandscience.
com.
New
Genome Duplication
Melvin DePamphilis, National Institute of Child Health and Human Development,
USA, and Stephen Bell, University of Oxford, UK
Genome Duplication provides a comprehensive and
readable overview of the underlying principles that
govern genome duplication in all forms of life, from
the simplest cell to the most complex multicellular
organism.
Using examples from the three domains of life - bacte-
ria, archaea, and eukarya - Genome Duplication shows
how all living organisms store their genome as DNA
and how they all use the same evolutionary-conserved
mechanism to duplicate it: semi-conservative DNA
replication by the replication fork. The text shows how
the replication fork determines where organisms begin genome duplication, how
they produce a complete copy of their genome each time a cell divides, and how
they link genome duplication to cell division.
Genome Duplication explains how mistakes in genome duplication are associ-
ated with genetic disorders and cancer, and how understanding genome duplica-
tion, its regulation, and how the mechanisms differ between different forms of
life, is critical to the understanding and treatment of human disease.
Contents:
1. Genomes 2. Life 3. Replication Forks 4. Replication Proteins: leading strand
synthesis 5. Replication Proteins: lagging strand synthesis 6. Termination 7. Chro-
matin Assembly Cohesion and Modification 8. Replicons 9. Replication Origins
10. Origin Paradigms 11. Initiation 12. Cell Cycles 13. Checkpoints 14. Human
Disease 15. Evolution of Cellular Replication Machineries
Garland Science
October 2010: 400pp: 200 illus, 50 tables, 50 halftones, 150 line drawings
Pb: 978-0-415-44206-0: £49.00
SUPPLEMENT:
Artwork available at www.garlandscience.com.
Garland Science
8 Website: www.garlandscience.com

new
Human Genetics: The Basics
Ricki Lewis, Alden March Bioethics Institute, Albany Medical College, USA
Human genetics has blossomed from an obscure branch of
biological science and occasional explanation for exceed-
ingly rare disorders to a field all of its own that affects
everyone. Human Genetics: The Basics introduces the
key questions and issues in this emerging field, including
the common ancestry of all humanity; the role of genes in
sickness and health; and debates over the use of genetic
technology. Written in an engaging, narrative manner, this
concise introduction is an ideal starting point for anyone
who wants to know more about genes, DNA, and the
genetic ties that bind us all.
Contents:
1. From Ancestry to Destiny 2. From Mendel’s Peas to Double Helices 3. How
Genes Work 4. Genes and Health 5. Genetic Testing 6. Genetic and Genomic
Technologies
Routledge
November 2010: 240 pp; 24 illustrations
Hb: 978-0-415-57984-1: £55.00
Pb: 978-0-415-57986-5: £11.99
E-book available at www.ebookstore.tandf.co.uk
Gene Control
David Latchman, Birkbeck, University of London, UK
Gene Control offers a current description of how gene
expression is controlled in eukaryotes, reviewing and
summarizing the extensive primary literature into an
easily accessible format. Gene Control is a comprehen-
sively restructured and expanded edition of Latch-
man’s Gene Regulation: A Eukaryotic Perspective, Fifth
Edition.
The first part of the book deals with the fundamental
processes of gene control at the levels of chromatin
structure, transcription, and post-transcriptional proc-
esses. Three pairs of chapters deal with each of these
aspects, first describing the basic process itself, followed by the manner in which
it is involved in controlling gene expression. The second part of the book deals
with the role of gene control in specific biological processes. Certain chapters
deal with the importance of gene control in cellular signaling processes and for
normal development of the embryo. Another chapter discusses the key roles
played by gene-regulatory processes in the specification of differentiated cell
types such as muscle cells and neurons. The final chapters discuss the conse-
quences of errors in gene control; the relationship between gene misregulation
and human diseases, especially cancer; and potential therapies designed specifi-
cally to target particular levels of gene control.
Gene Control will be of value to students in biological sciences, as well as to
scientists and clinicians interested in how genes are regulated in health and
disease.
Contents:
1. Levels of Gene Control 2. Structure of Chromatin 3. Role of Chromatin Struc-
ture in Gene Control 4. The Process of Transcription 5. Transcription Factors and
Transcriptional Control 6. Post-transcriptional Processes 7. Post-transcriptional
Regulation 8. Gene Control and Cellular Signaling Pathways 9. Gene Control in
Embryonic Development 10. Control of Cell-type-specific Gene Expression 11.
Gene Regulation and Cancer 12. Gene Regulation and Human Disease 13. Con-
clusions and Future Prospects
Garland Science
February 2010: 420pp: 17 tables, 56 halftones, 596 line drawings
Pb: 978-0-8153-6513-6: £46.00
SUPPLEMENT:
Artwork available at www.garlandscience.com.
com
@ E-mail: garlanduk@tandf.co.uk
for more information
@GarlandScience
genetics 7
Statistical Genetics
Gene Mapping Through Linkage and Association
Edited by Benjamin Neale, Center for Human Genetic Research, Massachusetts
General Hospital, USA, Manuel Ferreira, Massachusetts General Hospital, USA,
Sarah Medland, Virginia Commonwealth University, USA, and
Danielle Posthuma, Vrije University, The Netherlands
Statistical Genetics is an advanced textbook focusing on
conducting genome-wide linkage and association analy-
sis in order to identify the genes responsible for complex
behaviors and diseases. Starting with an introductory
section on statistics and quantitative genetics, it covers
both established and new methodologies, providing the
genetic and statistical theory on which they are based.
Each chapter is written by leading researchers, who give
the reader the benefit of their experience with worked
examples, study design, and sources of error.
The text can be used in conjunction with an associated
website (www.genemapping.org) that provides supplementary material and
links to downloadable software.
Contents:
1. Introduction 2. DNA 3. Introduction to Biometrical Genetics 4. Introduction to
Statistics 5. Statistical Power 6. Population Genetics and its Relevance to Gene
Mapping 7. Principles of Linkage Analysis 8. IBD Estimation 9. Regression Meth-
ods for Linkage Analysis 10. Variance Components Linkage Analysis for Quanti-
tative Traits 11. Extensions to Univariate Linkage Analysis 12. QTL Detection in
Multivariate Data from Sibling Pairs 13. Factors Affecting Type I Error and Power
of Linkage Analysis 14. Introduction to Association 15. Single-locus Association
Models 16. Genome-wide Association 17. Haplotype Estimation 18. Multi-locus
Association Models 19. Linkage Disequilibrium and Tagging 20. Haploview 21.
Factors Affecting Type I Error and Power in Association 22. Resampling Ap-
proaches to Statistical Interference
Taylor & Francis
2007: 608pp: 150 tables, 9 halftones, 55 line drawings
Pb: 978-0-415-41040-3: £48.00
Gene Cloning
Julia Lodge, Peter Lund, and Steve Minchin, all at the University of Birmingham, UK
The ability to successfully clone genes underlies the
majority of our knowledge in molecular and cellular
biology. Gene Cloning introduces the diverse array of
techniques available to clone genes and how they can
be used effectively both in the research laboratory, to
gain knowledge about the gene, and for use in biotech-
nology, medicine, the pharmaceutical industry, and
agriculture. It shows how cloning genes is an integral
part of genomics and underlines its relevance in the
post-genomic age, as a tool required to test predictions
of gene regulation and function made through bioinfor-
matics.  Applications of gene cloning in medicine, both
for diagnosis and treatment, and in the pharmaceutical industry and agriculture,
are also covered in the book.
Gene Cloning takes a fresh approach to teaching molecular and cellular biology
and will be a valuable resource to both undergraduates and lecturers of
biological and biomedical science courses.
Contents:
1. Introduction 2. Genome Organization 3. Key Tools for Gene Cloning 4. Gene
Identification and DNA Libraries 5. Screening DNA Libraries 6. Further Routes to
Gene Identification 7. Sequencing DNA 8. Bioinformatics 9. Production of Pro-
teins from Cloned Genes 10. Gene Cloning in the Functional Analysis of Proteins
11. The Analysis of the Regulation of Gene Expression 12. The Production and
Uses of Transgenic Organisms 13. Forensic and Medical Applications
Taylor & Francis
2006: 356pp: 11 tables, 6 halftones, 198 line drawings
Pb: 978-0-7487-6534-8: £36.00
SUPPLEMENT:
Artwork available at www.garlandscience.com.
8 E-bookstore: www.ebookstore.tandf.co.uk
eBooks are only available to order online
 8 genetics
Third Edition
Genomes 3
T.A. Brown, University of Manchester, UK
Covering molecular genetics from the basics through to
genome expression and molecular phylogenetics, Ge-
nomes 3 is the latest edition of this pioneering textbook.
Updated to incorporate the recent major advances,
Genomes 3 is an invaluable companion for any under-
graduate throughout their studies in molecular genetics.
Genomes 3 builds on the achievements of the previous
two editions by putting genomes, rather than genes, at
the centre of molecular genetics teaching. Recognizing
that molecular biology research was being driven more
by genome sequencing and functional analysis than by
research into genes, this approach has gathered momentum in recent years.
Contents:
Part 1: Studying Genomes
1. Genomes, Transcriptomes and Proteomes 2. Studying DNA 3. Mapping
Genomes 4. Sequencing Genomes 5. Understanding a Genome Sequence 6.
Understanding How a Genome Functions
Part 2: Genome Anatomies
7. Eukaryotic Nuclear Genomes 8. Genomes of Prokaryotes and Eukaryotic
Organelles 9. Virus Genomes and Mobile Genetic Elements
Part 3: How Genomes Function
10. Accessing the Genome 11. Assembly of the Transcription Initiation Complex
12. Synthesis and Processing of RNA 13. Synthesis and Processing of the Pro-
teome 14. Regulation of Genome Activity
Part 4: How Genomes Replicate and Evolve
15. Genome Replication 16. Mutations and DNA Repair 17. Recombination 18.
How Genomes Evolve 19. Molecular Phylogenetics
Garland Science
2006: 736pp: 550 illus
Pb: 978-0-8153-4138-3: £49.00
Packaged with a CD-ROM
supplements:
• Classwire (online course management system and library of teaching
resources) www.classwire.com/garlandscience
• CD-ROM containing all of the book’s figures.
RNAi
Edited by Martin Latterich, Form Consulting, Inc., USA
RNAi covers the basic concepts and mechanisms of RNAi, transfection of cells
with siRNAs, the design and validation of RNAi reagents, RNAi techniques in
different organisms, large-scale RNAi screening, applications of RNAi in drug dis-
covery, and potential uses of RNAi as a therapeutic agent. A key feature of RNAi
is the highlighting of the pitfalls that can occur and how to minimize them. The
book also contains a complete list of abbreviations.
Contents:
1. Methods in RNA Interference 2. RNAi Reagent Design 3. RNA Interference
- A Chemical Perspective 4. Validation of RNAi 5. RNA Interference Libraries in
Dissecting Molecular Pathways of the Human Cell 6. High-Throughput RNAi in
Caenorhabditis elegans - From Molecular Phenotypes to Pathway Analysis 7.
RNAi in Xenopus laevis 8. Generation of Transgenic and Knockdown Mice with
Lentiviral Vectors and RNAi Techniques 9. RNAi in Fungi
BIOS Advanced Methods
Taylor & Francis
2007: 150pp
Pb: 978-0-415-40950-6: £45.00
E-book available at www.ebookstore.tandf.co.uk
ORDER NOW!
See Order Form in the
center of this catalog ' Phone: +44 (0)1235 400524
Human Evolutionary Genetics
Origins, Peoples and Disease
Mark Jobling, University of Leicester, UK, Matthew Hurles and
Chris Tyler-Smith, both at Wellcome Trust Sanger Institute Cambridge, UK
‘I strongly recommend Human Evolutionary
Genetics as an undergraduate textbook. At
the same time, I recommend this book to any
readers with an interest in human evolution or
human genetics.’
Human Genetics
Human Evolutionary Genetics is a groundbreaking text
which for the first time brings together molecular genet-
ics and genomics to the study of the origins and move-
ments of human populations. Starting with an overview
of molecular genomics for the non-specialist (which can be a useful review for
those with a more genetic background), the book shows how data from the post-
genomic era can be used to examine human origins and the human colonization
of the planet, richly illustrated with genetic trees and global maps. For the first
time in a textbook, the authors outline how genetic data and the understand-
ing of our origins which emerges, can be applied to contemporary population
analyses, including genealogies, forensics and medicine.
Contents:
Section 1: Introduction
1. Why Study Human Evolutionary Genetics?
Section 2: How do we study Genome Diversity?
2. Structure, Function and Inheritance of the Human Genome 3. The Diversity of
the Human Genome 4. Discovering and Assaying Genome Diversity
Section 3: How do we Interpret Genetic Variation?
5. Processes Shaping Diversity 6. Making Inferences from Diversity
Section 4: Where and When did Humans Originate?
7. Human Apes 8. Origins of Modern Humans
Section 5: How did Humans Colonize the World?
9. The Distribution of Diversity - Out of Africa and into Asia, Australia and Europe
10. Agricultural Expansions 11. Into New Found Lands 12. What Happens When
Populations Meet?
Section 6: What use is an Evolutionary Perspective?
13. Understanding the Past and Future of Phenotypic Variation 14. Health Impli-
cations of Our Evolutionary Heritage 15. Identity and Identification
Garland Science
2003: 458pp
Pb: 978-0-8153-4185-7: £45.50
SUPPLEMENT:
Artwork available at www.garlandscience.com.
Working With DNA
Stan Metzenberg, California State University, USA
Working with DNA is a guide to the materials and methods that are used in the
recombinant DNA laboratory and is designed to help the novice understand how
specific laboratory techniques work, but also has sections that may stimulate the
thinking of experienced researchers. It isn’t a book of step-by-step protocols and
recipes, but is intended to broaden and strengthen the foundation of the reader
so that working with DNA becomes more natural and make them aware of the
many ways that a molecular research question may be addressed.
Contents:
1. Understanding Recombinant DNA Techniques 2. The Recombinant DNA Labo-
ratory 3. Solutions, Buffers, Stocks and Cocktails 4. Cloning Vectors 5. Restriction
Endonucleases 6. Polymerases 7. The Polymerase Chain Reaction 8. Working
with DNA: the reasons
The Basics
Taylor & Francis
2007: 410pp
Pb: 978-0-415-37464-4: £35.00
Garland Science
8 Website: www.garlandscience.com
 microbiology 9

Microbiology Student Resource Website (www.garlandscience.com/micro)

l E-Tutor The E-Tutor provides guidance for answering all of the questions
A Clinical Approach found at the end of each chapter of the book.
Anthony Strelkauskas, Trident Technical College, USA, Jennifer Strelkauskas, l MicroMovies A number of short movies (animations and videos) were cre-
Doctor of Veterinary Medicine, Oregon, USA, and ated that will help students understand the concepts presented in the book.
Danielle Moszyk-Strelkauskas, MD, Naval Medical Center, San Diego, USA l Bug Parade The Bug Parade is an enhanced version of the Pathogen List
Microbiology: A Clinical Approach is a new and unique found at the end of the book.
microbiology textbook for health science students study- l Interactive Flashcards and Searchable Glossary Interactive Flashcards and a
ing microbiology. It is clinically-relevant and uses the Searchable Glossary are available on the student resource site, and will help
theme of infection as its foundation. The book includes students master unfamiliar terms.
innovative chapters on emerging infectious diseases, l Student Lecture Notes These topical outlines are designed to help students
antibiotic resistance, and bioterrorism not seen in other follow a lecture on a particular chapter.
textbooks. Garland Science
Microbiology is student-friendly: its text, figures and January 2010: 733pp: 630 full-color illustrations
electronic resources have been carefully designed to help Pb: 978-0-8153-6514-3: £46.00
students understand difficult concepts and to keep them
interested in the material. The textbook is supported with a robust ancillary pack-
age for instructors which will easily allow them to incorporate the book’s new
approach into their lectures. Students working towards careers in the healthcare New Fourth Edition
professions will achieve success with Microbiology: A Clinical Approach.
BIOS Instant Notes in Microbiology
Simon Baker, Oxford Brookes University, UK, Jane Nicklin, Birkbeck, University of
Contents:
London, UK and Caroline Griffiths, Oxford Brookes University, UK
PART I FOUNDATIONS
1. What Is Microbiology and Why Does It Matter? 2. Fundamental Chemistry for SERIES FEATURES
Microbiology 3. Essentials of Metabolism 4. An Introduction to Cell Structure and • Affordably priced.
Host–Pathogen Relationships • Contains all of the essential facts that a student needs
PART II DISEASE MECHANISMS to know in a concise book–accessible, easy to read,
5. Requirements for Infection 6. Transmission of Infection, the Compromised approachable.
• Excellent for review ahead of examinations.
Host, and Epidemiology 7. Principles of Disease 8. Emerging and Re-Emerging
Infectious Diseases
BIOS Instant Notes in Microbiology, Fourth Edition, is a
PART III CHARACTERISTICS OF DISEASE-CAUSING MICROORGANISMS
concise microbiology textbook for undergraduates.  All
9. The Clinical Significance of Bacterial Anatomy 10. Bacterial Growth 11. Mi-
of the important areas of microbiology are covered in a
crobial Genetics and Infectious Disease 12. The Structure and Infection Cycle of
format that is ideal for learning and rapid revision.  Each
Viruses 13. Viral Pathogenesis 14. Parasitic and Fungal Infections topic begins with a summary of the essential facts – an ideal revision checklist
PART IV HOST DEFENSE – followed by a description of the subject that focuses on the core information,
15. The Innate Immune Response 16. The Adaptive Immune Response 17. Fail- with clear simple diagrams that are easy for students to understand and recall in 
ures of the Immune Response essays and examinations.
PART V CONTROL AND TREATMENT
BIOS Instant Notes in Microbiology, Fourth Edition, is fully up-to-date and
18. Control of Microbial Growth with Disinfectants and Antiseptics 19. Antibiotics
covers:
20. Antibiotic Resistance
• The microbial world • Systematics • Microbiology • Microbial Growth •
PART VI MICROBIAL INFECTIONS
Microbial Metabolism • Prokaryotic DNA and RNA metabolism • Industrial
21. Infections of the Respiratory System 22. Infections of the Digestive System
Microbiology • Eukaryotic microbes: an overview • The fungi and related phyla •
23. Infections of the Genitourinary System 24. Infections of the Central Nervous
Archaeplastida, Excavata, Chromalveolata and Amoebozoa • The viruses
System 25. Infections of the Blood 26. Infections of the Skin and Eyes
PART VII THE BEST AND THE WORST; IMPORTANT ISSUES IN MICROBIOLOGY BIOS Instant Notes
27. Biotechnology 28. Bioterrorism • Answers to Questions • Glossary • Taylor & Francis
Pathogen List • Figure Acknowledgements • Index March 2011: 341pp: 306 illustrations
Pb: 978-0-415-60770-4: £20.00
Instructor Resources E-book available at www.ebookstore.tandf.co.uk
l The Art of Microbiology: A Clinical Approach The images from the book are SUPPLEMENT:
available in two convenient formats: Power Point® and JPEG. Artwork available at www.garlandscience.com.
l Instructor’s Manual To facilitate the design of a course around this book, the
authors provide: a sample syllabus, based on their course; detailed guidance
on each chapter; presentation strategies; clinical connections; instructional
goals; and discussion of potential problem areas for students.
l Instructor’s Lecture Outlines These PowerPoint presentations provide a
complete set of lecture outlines for this course integrated with illustrations
and tables from the book.
l MicroMovies Short movies have been developed to complement material in
a select number of chapters, with a special emphasis on molecular genetics,
virology, and immunology.
l Instructor’s Media Guide This PDF overviews the multimedia package avail-
able for students and instructors.
l Question Bank Contains over 800 questions in a variety of formats: multiple
choice, true-false, fill-in-the-blank, matching, and depth-of-understanding
questions organized by book chapter.
l Diploma® Computerized Question Bank The questions from the question
bank have been loaded into the Diploma test generator software, which can
scramble questions to create multiple tests.
l Classwire™ The instructor’s supplements described above are available
online via the Classwire course management system.
www.classwire.com/garlandscience

com
@ E-mail: garlanduk@tandf.co.uk
for more information
@GarlandScience
8 E-bookstore: www.ebookstore.tandf.co.uk
eBooks are only available to order online
10 microbiology
New Second Edition
Marine Microbiology
Ecology & Applications
Colin Munn, University of Plymouth, UK
New tools and an increased interest in ecological factors
have caused an upsurge of interest in this field of study. The
book aims to convey the fascinating discoveries and great
importance of this fast moving discipline to the student.
Marine Microbiology is divided into three sections: the first
reviews the main features of the marine environment and
key aspects of marine microbial life; the second looks at the
role of marine microorganisms in ecology, and the final sec-
tion considers some of the applications of this knowledge,
looking into areas such as disease and biodegradation.
KEY FEATURES:
• Provides an understanding of microbial biology and ecology with considera-
tion of the applications for environmental management, human welfare,
health and economic activity in the marine environment.
• Contains new material on the application of molecular techniques (especially
metagenomics), metabolic diversity and ecophysiology, climate change and
ocean acidification.
• Includes new ‘Research Focus’ boxes which explore in detail topical areas of
investigation.
• Integrates ‘Information’ boxes and ‘Question’ boxes throughout the text
which encourages the reader to think about an important issue where knowl-
edge is incomplete or there are differences of opinion.
• Aimed at upper level undergraduates, Master’s degree students and re-
searchers in the fields of marine biology, oceanography, microbiology, aquatic
ecology, and environmental sciences.
CONTENTS:
1. Microbes in the Marine Environment 2. Methods in Marine Microbiology 3.
Metabolic Diversity and Ecophysiology 4. Marine Bacteria 5. Marine Archaea
6. Marine Eukaryotic Microbes 7. Marine Viruses 8. Ocean Processes - Marine
Microbes and the Carbon Cycle 9. Nutrient Cycles - Nitrogen, Sulphur and
Phosphorus 10. Symbiotic Associations 11. Microbial Diseases of Marine Organ-
isms 12. Marine Microbes as Agents of Human Disease 13. Microbial Aspects
of Marine Biofouling, Biodeterioration and Pollution 14. Marine Microbes and
Biotechnology
Garland Science
March 2011: 320pp: 131 illustrations
Pb: 978-0-8153-6517-4: £41.00
E-book available at www.ebookstore.tandf.co.uk
New
Viruses
Biology, Application, and Control
David R Harper, Biocontrol Limited, UK
Viruses: Biology, Application, and Control is a concise advanced undergraduate
and graduate textbook covering the essential aspects of virology included in bio-
medical science courses. It is an updated and expanded version of David Harper’s
Molecular Virology, Second Edition.
The first chapters introduce the reader to the structure and nature of viruses,
including their classification and evolution. Viruses cause widespread and serious
disease so the next chapters explain how they interact with the immune system
and the different ways we try to defeat them: vaccines, antiviral drugs, and im-
munotherapy. There is also coverage of laboratory methods for viral detection
and laboratory diagnosis. While viruses do cause disease, many do not and their
special biology means they can have beneficial uses and this aspect of viruses is
not neglected. One of the most interesting areas in virology, and one given exten-
sive coverage here, is how new viruses emerge and establish themselves.
Viruses: Biology, Application, and Control is a rigorous treatment of the mo-
lecular side of virology and its conceptual approach makes it an essential text for
students and non-specialists.
KEY FEATURES:
l Viral replication strategies of the major virus groups causing human infec-
tions are included in a dedicated appendix
ORDER NOW!
See Order Form in the
center of this catalog ' Phone: +44 (0)1235 400524
l Covers the emergence of new viruses, for example SARS, bird flu, and Ebola,
and attempts to eradicate known viruses, such as Smallpox and polio
l Includes the beneficial use of viruses in gene therapy and genetic manipula-
tion
l Key concepts at the end of each chapter to help learning
l End of chapter questions will test understanding
l Further reading at the end of each chapter for readers who want to pursue
concepts further
CONTENTS:
1. Virus Structure and Infection 2. Virus Classification and Evolution 3. Virus
Replication 4. Viral Interaction with the Immune System 5. Vaccines and Im-
munotherapy 6. Antiviral Drugs 7. Beneficial Use of Viruses 8. Emergence and
Extinction of Viruses 9. Virus Culture, Detection and Diagnosis • Appendix: Virus
Replication Strategies and Characteristics by Family
Garland Science
June 2011: 300pp: 400 illustrations
Pb: 978-0-8153-4150-5: £41.00
E-book available at www.ebookstore.tandf.co.uk
SUPPLEMENT:
Artwork available at www.garlandscience.com.
Living in a Microbial World
Bruce Hofkin, University of New Mexico, USA
Living in a Microbial World is a textbook written for
students taking a general microbiology or microbiology-
themed course for non-science majors. It teaches the
essential concepts of microbiology through practical
examples and a conversational writing style intended to
make the material accessible to a wide audience.
In order to make the science relevant to students, every
chapter of the book contains a series of cases intended
to motivate learning the microbiology concepts. The
cases present microbiology in the news, in history, in
literature, and in scenarios of everyday life. Each case
ends with several questions intended to pique student
interest, and those questions are answered in the next section of the chapter.
By clearly and succinctly explaining the fundamentals of microbiology through
practical examples, the book provides a scientific framework through which
students can understand critical issues about microorganisms and disease
that they will encounter throughout their lives. They will learn the role that
microorganisms play not only in our health but also in ecosystem processes, our
diet, industrial production, and human history. Topics that we hear about every
day, from global warming to energy independence to bioterrorism, all have a
microbial angle. This text is designed to provide the reader with the background
needed to understand and discuss such topics with a genuine understanding
rooted in science.
Contents:
1. Living in a Microbial World 2. The Chemistry of Life 3. The Cell: Where Life
Begins 4. A Field Guide to the Microorganisms 5. The Microbiology of History and
the History of Microbiology 6. An Introduction to Microbial Genetics 7. Microbial
Metabolism and Growth 8. Microbial Evolution and the Origin of Life 9. An Ecolo-
gist’s Guide to Microbiology 10. The Disease Process: A Pathogen’s Perspective
11. Host Defense 12. Control of Microbial Growth 13. Epidemiology: Who, What,
When, Where, and Why? 14. The Future is Here: Microorganisms and Biotech-
nology 15. Guess Who’s Coming to Dinner? Microorganisms and Food 16. Better
Living with Microorganisms: Industrial and Applied Microbiology
Garland Science
June 2010: 512pp: 400 illus
Pb: 978-0-8153-4175-8: £42.00
Supplements:
Artwork available at www.garlandscience.com.
• The Art of Living in a Microbial World
• Online Glossary.
• Online Student Quizzes
• Online Student Flash Cards.
• Microbiology Movies
Garland Science
8 Website: www.garlandscience.com

New
Protozoa and Human Disease
Mark F. Wiser, Tulane University, USA
Protozoa and Human Disease is a textbook for advanced
undergraduate and graduate students studying parasitol-
ogy and microbiology. It will also be a useful reference for
public health and medical students.
Mark Wiser reviews medically important protozoa, and
treatment strategies.  He describes pathogens according
to a taxonomic scheme and in reference to the organ
systems they affect. The book covers the morphological
features and life cycles of the various protozoa and the
pathogeneses of the diseases they cause. Life cycles are
discussed in detail as they also influence host-parasite interactions, pathology,
disease transmission, and epidemiology.
Students will benefit from the author’s fresh approach, which blends clas-
sical and medical parasitology with more modern disciplines. These include
the molecular and immunological basis of pathogenesis; metabolic pathways;
specialized subcellular structures; ecology of disease transmission; antigenic vari-
ation; and molecular epidemiology. An extensive glossary of molecular biology,
immunology, and medical terms helps students navigate across disciplines.
CONTENTS:
1. Introduction to Medical Protozoology 2. Overview of Intestinal Protozoa 3.
Entamoeba and Amebiasis 4. Giardiasis 5. Trichomonas vaginalis and Other
Trichomonads 6. Balantidium coli and Blastocystis hominis 7. Kinetoplastids 8.
African Trypanosomiasis 9. Trypanosoma cruzi and Chagas’ Disease 10. Leishma-
niasis 11. General Apicomplexan Biology 12. Cryptosporidium 13. Monoxenous
Intestinal Coccidia 14. Toxoplasma gondii 15. Malaria 16. Babesiosis 17. Free-
Living Protozoa Affecting Human Health • Glossary
Garland Science
November 2010:250pp: 50 halftones, 200 line drawings
Pb: 978-0-8153-6500-6: £35.00
SUPPLEMENT:
Artwork available at www.garlandscience.com.
Case Studies in Infectious Disease
Peter Lydyard, Royal Free and University College Medical School, UK, Michael
Cole, Georgetown University Medical Center, USA, John Holton, Royal Free and
University College Medical School, UK, Will Irving, University of Nottingham, UK,
Nino Porakishvili, University of Westminster, UK, Pradhib Venkatesan,
Nottingham University Hospital, UK, and Kate Ward, Royal Free and University
College Medical School, UK
‘...it will interest students in microbiology as
much as it will interest clinical medical stu-
dents…a handsome, excellent book on most
common pathogens, with a clear orientation to
immunology, physiopathology, and microbiol-
ogy…It reads well and is an excellent textbook for
medical students and a good source of illustra-
tions, tables, and question ideas for teachers.’
Clinical Infectious Disease
Case Studies in Infectious Disease presents forty case studies featuring the most im-
portant human infectious diseases worldwide. Written for students of microbiology
and medicine, this book describes the natural history of infection from point of entry
of the pathogen through pathogenesis, clinical presentation, diagnosis and treat-
ment. The use of real clinical cases serves to reinforce and extend the basic science.
This standardized approach provides the reader with a logical basis for under-
standing these diverse and medically important organisms, fully integrating
microbiology and immunology throughout.
cases (now available individually in eBook format):
1. Aspergillus fumigatus 2. Borellia burgdorferi and related species 3. Campy-
lobacter jejuni Case 4. Chlamydia trachomatis 5. Clostridium difficile 6. Coxiella
burnetti 7. Coxsackie B virus 8. Echinococcus spp. 9. Epstein-Barr virus 10. Es-
cherichia coli 11. Giardia lamblia 12. Helicobacter pylori 13. Hepatitis B virus 14.
Herpes simplex virus 1 15. Herpes simplex virus 2 16. Histoplasma capsulatum
17. Human immunodeficiency virus 18. Influenza virus 19. Leishmania spp. 20.
Leptospira spp. 21. Listeria monocytogenes 22. Mycobacterium leprae 23. My-
cobacterium tuburculosis 24. Neisseria gonorrhoeae 25. Neisseria meningitidis
com
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microbiology 11
26. Norovirus 27. Parvovirus 28. Plasmodium spp. 29. Respiratory syncytial virus
30. Rickettsia spp. 31. Salmonella typhi 32. Schistosoma spp. 33. Staphlococcus
aureus 34. Streptococcus mitis 35. Streptococcus pneumoniae 36. Streptococcus
pyogenes 37. Toxoplasma gondii 38. Trypanosoma spp. 39. Varicella-zoster virus
40. Wuchereria bancrofti
Garland Science
May 2009: 608pp: 170 halftones, 100 line drawings
Pb: 978-0-8153-4142-0: £35.00
SUPPLEMENT:
Artwork available at www.garlandscience.com.
Emerging Protozoan Pathogens
Edited by Naveed Ahmed Khan, University of Nottingham, UK
Emerging protozoan pathogens, once thought to be an
obscure menace of society, have become a major threat
to human health. The last two decades have seen major
advances in the understanding of these increasingly
important pathogens. 
Emerging Protozoan Pathogens provides a comprehen-
sive account of up-to-date information on the present
status of research in this discipline. Written by experts
in their respective subject areas, this book provides a
valuable resource for microbiologists and molecular and
cell biologists at advanced undergraduate and graduate levels, as well as health
professionals and researchers who are interested in these pathogens. The mate-
rial covered, including biology, genomics, epidemiology, pathogenesis and treat-
ments, makes it an ideal platform on which to base further research projects.
Contents:
A. Amoebae A1. Acanthamoeba spp. A2. Balamuthia mandrillaris A3. Naegleria
fowleri A4. Blastocystis hominis B. Apicomplexans B1. Cryptosporidium spp. B2.
Toxoplasma gondii B3. Isospora belli B4. Babesia microti C. Ciliates C1. Balan-
tidium coli D. Flagellates D1. Diplomonadida - Giardia spp. D2. Stramenopila
- Trichomonas vaginalis E. Protozoan Pathogens of Major Medical Importance F.
Protozoan Biology G. Host Response
Taylor & Francis
2007: 384pp: 159 illus, 23 tables, 73 halftones, 86 line drawings
Pb: 978-0-415-42864-4: £45.50
E-book available at www.ebookstore.tandf.co.uk
Biology of Disease
Nessar Ahmed, Maureen Dawson, Chris Smith, all at Manchester Metropolitan
University, UK, and Ed Wood (deceased)
Biology of Disease describes the biology of many of the human disorders and
diseases that are encountered in a clinical setting. It is de-
signed for first and second year students in biomedical sci-
ence programs and will also be a highly effective reference
for health science professionals as well as being valuable
to students beginning medical school. Real cases are used
to illustrate the importance of biology in understanding the
causes of diseases, as well as in diagnosis and therapy.
Contents:
Preface • Glossary 1. The Nature and Investigation of Dis-
eases 2. Pathogens and Virulence 3. Infectious Diseases and
Treatments 4. The Immune System
5. Disorders of the Immune System 6. Transfusion and Transplantation
7. Disorders of the Endocrine System 8. Disorders of Water, Electrolytes and Urate
Balances 9. Disorders of Acid-Base Balance 10. Diet and Disease 11. Disorders of
the Gastrointestinal Tract, Pancreas, Liver and Gall Bladder 12. Toxicology 13. Dis-
orders of the Blood 14. Disease of the Cardiovascular System 15. Genetic Diseases
16. Membrane, Organelle and Cytoskeletal Disorders 17. Cancer 18. Ageing &
Disease • Case Study Discussions • Answers to Questions • Index
Taylor & Francis
2006: 600pp
Pb: 978-0-7487-7210-0: £36.00
E-book available at www.ebookstore.tandf.co.uk
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8 E-bookstore: www.ebookstore.tandf.co.uk
eBooks are only available to order online
 12 immunology
New Eighth Edition
Janeway’s Immunobiology
Kenneth M. Murphy at the Washington University School of Medicine, St. Louis,
USA.
Janeway’s Immunobiology is an introductory textbook for undergraduates,
graduate students, and medical students of immunology. It guides the reader
through the immune system in all its aspects–from the first engagement of
innate immunity to the generation of the adaptive immune response and its
clinical consequences.
The Eighth Edition has been completely updated as follows:
• Two separate chapters on innate immunity: Chapter 2 (Innate Immunity: The
First Lines of Defense) and Chapter 3 (The Induced Responses of Innate Im-
munity).
• Presentation of T cell subset including Th17 development and regulation.
• Revised treatment of signaling and immune regulation.
• Addition of new structural information and insight into the mechanisms of
innate recognition.
• Presentation of lymphocyte development.
• Coverage of the interactions of the commensal gut microbioata with the
mucosal immune system (Chapter 12).
• Evolution is now incorporated throughout the text.
Students and instructors will have access to supplements including animations
and videos with voiceover narration as well as the figures from the text for pres-
entation purposes. Janeway’s Immunobiology continues to set the standard for
relevancy and authority with its clear writing style and organization, full-color art
program, and scientific accuracy.
CONTENTS:
1. Basic Concepts in Immunology 2. Innate Immunity: The First Lines of Defense
3. The Induced Responses of Innate Immunity 4. Antigen Recognition by B-cell
and T-cell Receptors 5. The Generation of Lymphocytes Antigen Receptors 6.
Antigen Presentation to T Lymphocytes 7. Signaling Through Immune System Re-
ceptors 8. The Development and Survival of Lymphocytes 9. T-cell Mediated Im-
munity 10. The Humoral Immune Response 11. Dynamics of Adaptive Immunity
12. The Mucosal Immune System 13. Failures of Host Defense Mechanisms 14.
Allergy and Allergic Diseases 15. Autoimmunity and Transplantation 16. Evolution
of the Immune System
Garland Science
September 2011: 928pp: 599 illustrations
Pb: 978-0-8153-4243-4: £48.00
sUPPLEMENTs:
Artwork, original animations based on figures in the book, and videos selected
from visually compelling experiments are available at www.garlandscience.com.
ORDER NOW!
See Order Form in the
center of this catalog ' Phone: +44 (0)1235 400524
New Sixth Edition
Case Studies in Immunology
A Clinical Companion
Raif Geha and Luigi Notarangelo, both at Harvard Medical School, USA
Case Studies in Immunology, Sixth Edition, is intended for medical students and
undergraduate and graduate students in immunology and presents major topics
of immunology through a selection of clinical cases that reinforce and extend the
basic science. The case histories illustrate essential points about the mecha-
nisms of immunity and describe immunological problems seen in the clinic. This
new edition vividly illustrates the importance of an understanding of immunol-
ogy in diagnosis and therapy.
Case Studies in Immunology highlights major common disorders of immunity,
including hypersensitivity types I-IV, immune deficiencies, and autoimmune
disorders. Each case history is preceded by basic scientific facts essential to
understanding the immunology behind the specific disorders. An end-of-case
summary, questions, and discussion points conclude each case. The book in-
cludes a total of 53 cases and can be used as either a stand-alone text, review aid,
or as a companion to Janeway’s Immunobiology, Eighth Edition, and The Immune
System, Third Edition. The Sixth Edition is extensively revised and updated and
includes ten new cases.
CASES:
1. X-linked Agammaglobulinemia 2. CD40 Ligand (CD40L) Deficiency 3.
Activation-induced Cytidine Deaminase (AID) Deficiency 4. Common Variable
Immunodeficiency 5. X-linked Severe Combined Immunodeficiency 6. Adeno-
sine Deaminase Deficiency 7. Omenn Syndrome 8. MHC Class II Deficiency 9.
DiGeorge Syndrome 10. Acquired Immune Deficiency Syndrome (AIDS) 11. Graft-
Versus-Host Disease 12. MHC Class I Deficiency 13. X-linked Lymphoproliferative
Syndrome 14. Familial Hemophagocytic Lymphohistocytosis 15. Chediak-Higashi
Syndrome 16. Wiskott-Aldrich Syndrome 17. Autoimmune Polyendocrinopathy-
Candidiasis-Ectodermal Dystrophy 18. Immune Dysregulation, Polyendocrin-
opathy, Enteropathy X-linked Disease 19. Autoimmune Lymphoproliferative
Syndrome (ALPS) 20. Hyper IgE Syndrome 21. Ataxia-telangiectasia 22. Warts,
Hypogammaglobulinemia, Infections, and Myelokathexis (WHIM) Syndrome
23. X-linked Hypohydrotic Ectodermal Dysplasia and Immunodeficiency 24.
Interferon-γ Receptor Deficiency 25. Severe Congenital Neutropenia 26. Chronic
Granulomatous Disease 27. Leukocyte Adhesion Deficiency 28. Recurrent Herpes
Simplex Encephalitis 29. Interleukin 1 Receptor-associated Kinase 4 Deficiency
30. Congenital Asplenia 31. Hereditary Angioedema 32. Factor I Deficiency 33.
Deficiency of the C8 Complement Component 34. Hereditary Periodic Fever
Syndromes 35. Juvenile Arthritis 36. Rheumatoid Arthritis 37. Systemic Lupus
Erythematosus 38. Mixed Essential Cryoglobulinemia 39. Crohn’s Disease 40.
Multiple Sclerosis 41. Autoimmune Hemolytic Anemia 42. Myasthenia Gravis 43.
Pemphigus Vulgaris 44. Celiac Disease 45. Acute Infectious Mononucleosis 46.
Hemolytic Disease of the Newborn 47. Toxic Shock Syndrome 48. Lepromatous
Leprosy 49. Acute Systemic Anaphylaxis 50. Allergic Asthma 51. Atopic Dermatitis
52. Drug-induced Serum Sickness 53. Contact Sensitivity to Poison Ivy • Answers
• Figure Acknowledgments • Index
Garland Science
October 2011: 400pp: 200 illustrations
Pb: 978-0-8153-4441-4: £35.00
sUPPLEMENT:
Artwork available at www.garlandscience.com.
Garland Science
8 Website: www.garlandscience.com

Third Edition
The Immune System
Peter Parham, Stanford University, USA
The Immune System, Third Edition emphasizes the
human immune system and synthesizes immunologi-
cal concepts into a comprehensible, up-to-date, and
reader-friendly account of how the immune system
works. Written for undergraduate, medical, dental, and
pharmacy students in immunology courses, it makes
generous use of medical examples to illustrate points.
The Third Edition has been extensively revised and
updated and includes two new chapters on innate and
adaptive immunity, which explore the physical, cellular,
and molecular principles underlying these responses to
infection. It also features enhanced coverage of aspects of innate immunity such as
the complement system, Toll-like receptors, defensins, and C-reactive protein; the
role of dendritic cells in initiating the primary adaptive immune response and the
functions of other cells that bridge innate and adaptive immunity; immunothera-
pies using humanized monoclonal antibodies to treat certain diseases; and the na-
ture of the immune response in the mucosal tissues and immunological memory.
The book offers over 500 full-color illustrations that complement and clarify the
concepts. The end-of-chapter questions have been expanded and include essay,
multiple-choice, and case study questions, with answers provided at the end of
the book.
Contents:
1. Elements of the Immune System and Their Roles in Defense 2. Innate Immu-
nity 3. Principles of Adaptive Immunity 4. Antibody Structure and the Generation
of B-Cell Diversity 5. Antigen Recognition by T Lymphocytes 6. The Development
of B Lymphocytes 7. The Development of T Lymphocytes 8. T Cell-Mediated Im-
munity 9. Immunity Mediated by B Cells and Antibodies 10. The Body’s Defenses
Against Infection 11. Failures of the Body’s Defenses 12. Over-reactions of the
Immune System 13. Disruption of Healthy Tissue by the Immune Response 14.
Prevention of Infectious Disease by Vaccination 15. Transplantation of Tissues
and Organs 16. Cancer and its Interaction with the Immune System
Garland Science
January 2009: 608pp: 513 illus, 37 halftones, 476 line drawings
Pb: 978-0-8153-4146-8: £41.00
SUPPLEMENTS:
l The Art of The Immune System, Third Edition: 978-0-8153-4429-2: £33.00.
l Question Bank: features over 500 essay and multiple choice questions and
includes detailed answers to all questions.
l Lecture outlines from the book’s concept heads are available in PowerPoint®
format.
l Garland Science Classwire (course management system and library of
reading resources) www.classwire.com/garlandscience
New Third Edition
BIOS Instant Notes in Immunology
Peter Lydyard, Royal Free and University College Medical School, UK, Alex Whe-
lan, Trinity College Dublin, UK, and Michael Fanger, Dartmouth Medical School,
USA
SERIES FEATURES
• Affordably priced.
• Contains all of the essential facts that a student needs Pb: 978-0-8153-4443-8: £46.00
to know in a concise book–accessible, easy to read, E-book available at www.ebookstore.tandf.co.uk
approachable.
• Excellent for review ahead of examinations.
BIOS Instant Notes in Immunology, Third Edition, is a con-
cise immunology textbook for undergraduates.  All of the
important areas of immunology are covered in a format
that is ideal for learning and rapid revision.  Each topic begins with a summary of
the essential facts – an ideal revision checklist – followed by a description of the
subject that focuses on the core information, with clear, simple diagrams that are
easy for students to understand and recall in essays and examinations. 
com
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immunology 13
BIOS Instant Notes in Immunology, Third Edition, is fully up-to-date and covers:
• Overview of the immune system • Cells and molecules of the innate immune
system • The adaptive immune system • Antibodies • The antibody response
• The T cell response – cell-mediated immunity • Regulation of the immune
response • Immunity to infection • Vaccination • mmunodeficiency – when the
immune system fails • Hypersensitivity – when the immune system misbehaves •
Autoimmunity and autoimmune diseases • Transplantation • Tumor immunology
• Gender and the immune system • Aging and the immune system (immunose-
nescence) • Immunotherapy
BIOS Instant Notes
Taylor & Francis
March 2011: 340pp: 170 illustrations
Pb: 978-0-415-60753-7: £20.00
E-book available at www.ebookstore.tandf.co.uk
SUPPLEMENT:
Artwork available at www.garlandscience.com.
New
Mucosal Immunology
Society for Mucosal Immunology. Edited by Phillip D. Smith, University of
Alabama at Birmingham, USA, Richard S. Blumberg, Harvard Medical School,
USA, and Thomas T. MacDonald, Barts and the London School of Medicine and
Dentistry, UK.
Mucosal Immunology is intended for advanced undergraduate and graduate stu-
dents in immunology and microbiology, medical students, and dental students.
It presents the basic and clinical aspects of the mucosal immune system, focusing
on the major components of the mucosal barrier-the gastrointestinal, genitouri-
nary, and respiratory tract surfaces. Topics include the cellular consituents of the
mucosal immune system, host-microbe relationships, infection, mucosal diseas-
es, and vaccines. Mucosal Immunology is sponsored by the Society for Mucosal
Immunology and is written by internationally recognized leaders in the field.
CONTENTS:
1. Basic Principles of Mucosal Immunology 2. Ontogeny and Phylogeny 3.
Structure and Histology of the Mucosal Layers 4. Distinctive Features of Mucosa-
Associated Lymphoid Function 5. Non-structural Protective Factors - Mucus and
Antimicrobial Factors 6. Epithelial Cells 7. Intraepithelial Cells 8. Lymphocytes - T
Cells 9. Regulatory Cells and Networks 10. Lymphocytes - B Cells 11. Secretory
Immunoglobulins and Their Transport 12. Dendritic Cells 13. Lamina Propria
Macrophages 14. Mucosal Basophils and Mast Cells
15. M Cells, Peyer’s Patches, and Isolated Lymphoid Follicles 16. Lymphocyte
Trafficking 17. Mucosal Tolerance 18. Role of the Microbiota in Mucosal Health
19. Host-Microbe Interactions 20. Pattern-Recognition Molecules 21. Response
to Microbiota Associated with Disease 22. Overview of the Genitourinary Tract
Immune System 23. Mucosal Immune Responses to Microbes 24. Immunobiol-
ogy of the Nasal, Upper Airway, and Oral Mucosae 25. Mucosal Immune System
of the Respiratory Tract 26. Heliobacter pylori Gastric Infection 27. Gut Bacterial
and Parasitic Infections 28. Viral Infections 29. Periodontal Disease 30. Celiac
Sprue 31. Mucosal Manifestations of Immunodeficiencies 32. Inflammatory
Bowel Disease 33. Food Sensitive and Eosinophilic Enteropathies 34. IgA Neph-
ropathy 35. Immune-mediated Respiratory Diseases 36. Principles of Mucosal
Vaccine Strategies
Garland Science
November 2011: 512pp: 250 full-color illustrations
SUPPLEMENT:
Artwork available at www.garlandscience.com.
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eBooks are only available to order online
14 STRUCTURAL BIOLOGY

New
Fields, Forces, and Flows in Biological Systems
Alan J Grodzinsky, Massachusetts Institute of Technology, USA
Fields, Forces, and Flows in Biological Systems de-
scribes the fundamental driving forces for mass trans-
port, electric current, and fluid flow as they apply to
the biology and biophysics of molecules, cells, tissues,
and organs. Basic mathematical and engineering tools
are presented in the context of biology and physiology.
The chapters are structured in a framework that
moves across length scales from molecules to mem-
branes to tissues. Examples throughout the text deal
with applications involving specific biological tissues,
cells, and macromolecules. In addition, a variety of
applications focus on sensors, actuators, diagnostics, and microphysical measure-
ment devices (e.g., bioMEMs/NEMs microfluidic devices) in which transport and
electrokinetic interactions are critical.
This textbook is written for advanced undergraduate and graduate students
in biological and biomedical engineering and will be a valuable resource for
interdisciplinary researchers including biophysicists, physical chemists, materials
scientists, and chemical, electrical, and mechanical engineers seeking a common
language on the subject.
Contents:
1. Chemical Transport in Electrolyte Media 2. Electric Fields and Flows in Elec-
trolyte Media 3. Electrochemical Coupling and Transport 4. Electrical Interaction
Forces: From Intramolecular to Macroscopic 5. Newtonian Fluid Mechanics
6. Electrokinetics: MEMs, NEMs, and Nano-porous Biological Tissues 7. Rheology
of Hydrated Biological Tissues and Polymeric Biomaterials
Garland Science
February 2011: 500pp: 200 illus
Hb: 978-0-8153-4212-0: £49.00
SUPPLEMENT:
Artwork available at www.garlandscience.com.
New
How Proteins Work
Michael Williamson, University of Sheffield, UK
How Proteins Work is a clear, up-to-date and authoritative account of the prin-
ciples that govern the way proteins work, and sets proteins within the context
in which they function: within the cell, within biological systems, and within the
limitations fixed by physics, chemistry, and evolution, taking examples from many
different areas of biology.
It provides an integrated view of proteins, showing how evolutionary pressure
has driven proteins to adopt a domain structure, and to put these domains
together in various combinations in order to achieve a biological outcome. 
The text demonstrates how the association of proteins into dimers, complexes
(molecular machines) and multi-enzyme complexes allows them to achieve
remarkable catalytic and functional efficiency.  It shows how evolution has led to
an accumulation of regulatory and scaffold proteins, particularly with reference
to signaling pathways; and it presents current views of protein dynamics and
interactions.
For postgraduates and researchers How Proteins Work provides an up-to-date
and coherent account of the relationship between protein function, structure
and dynamics.
Contents:
1. Protein Structure and Evolution 2. Protein Domains 3. Oligomers 4. Protein
Interactions in Vivo 5. How Enzymes Work 6. Protein Flexibility and Dynamics 7.
How Proteins Make Things Move 8. How Proteins Transmit Signals
9. Protein Complexes: Molecular Machines 10. Multi-Enzyme Complexes
11. Techniques for Studying Proteins
Garland Science
June 2011: 464 pp: 537 illus
Pb: 978-0-8153-4446-9: £46.00
E-book available at www.ebookstore.tandf.co.uk
SUPPLEMENT:
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New
Introduction to Proteins
Structure, Function, and Motion
Amit Kessel, Es-is Technologies Ltd., Givatayim, Israel
and Nir Ben-Tal, Tel Aviv University, Israel
Introduction to Proteins: Structure, Function, and Mo-
tion presents a unified, in-depth treatment of the rela-
tionship between the structure, dynamics, and function
of proteins. Taking a structural–biophysical approach,
the authors discuss the molecular interactions and
thermodynamic changes that transpire in these highly
complex molecules.

CONTENTS:
1. Introduction 2. Protein Structure 3. Methods of Structure Determination and
Prediction 4. Energetics and Protein Stability 5. Protein Structural Dynamics 6.
Non-Globular Proteins 7. Membrane Proteins 8. Protein–Ligand Interactions

CRC Press
December 2010: 654 pp
Hb: 978-1-439-81071-2: £49.99

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center of this catalog ' Phone: +44 (0)1235 400524 Garland Science
8 Website: www.garlandscience.com

Biomolecular Crystallography
Principles, Practice, and Application to Structural Biology
Bernhard Rupp, q.e.d. life science discoveries, California, USA
“Over the past 34 years Louise and I have often
discussed the possibility of updating [Protein
Crystallography]....However, this marvelous
text by Bernhard Rupp provides everything
that we could have done and more: indeed
all that is required for the student of 2010.
Biomolecular Crystallography is an impressive
volume. Its 808 pages are beautifully written
and wonderfully illustrated, many in colour....
This book will be an essential part of the library
of any department that claims to make contributions to modern biol-
ogy....[and] a necessary addition also to the libraries of big pharma-
ceutical companies and small biotechs. This is a book to be enjoyed by
all who wish to become structural biologists. I am also sure that many
practicing structural biologists - even some who consider themselves
mature - would do well to read its pages.”
Tom Blundell, Journal of Applied Crystallography
Synthesizing over thirty years of advances into a comprehensive textbook,
Biomolecular Crystallography describes the fundamentals, practices, and
applications of protein crystallography.  Deftly illustrated in full-color by the
author, the text describes mathematical and physical concepts in accessible and
accurate language. It distills key concepts for understanding the practice and
analysis of protein crystal structures and contains examples of
biologically-relevant molecules, complexes, and drug target structures.
Biomolecular Crystallography will be a valuable resource for advanced
undergraduate and graduate students and practitioners in structural biology,
crystallography, and structural bioinformatics.
Contents:
I: FROM SEQUENCE TO CRYSTALS
1. Introduction: Preparing Your Study 2. Protein Structure 3. Protein Crystalliza-
tion 4. Proteins for Crystallography
II: FUNDAMENTALS OF PROTEIN CRYSTALLOGRAPHY
5. Crystal Geometry 6. Diffraction Basics 7. Statistics and Probability in Crystal-
lography
III: FROM CRYSTALS TO DATA
8. Instrumentation and Data Collection
IV: DETERMINING YOUR STRUCTURE
9. Reconstruction of Electron Density and the Phase Problem 10. Experimental
Phasing 11. Non-Crystallographic Symmetry and Molecular Replacement 12.
Model Building and Refinement
V: MAKING SENSE OF YOUR STRUCTURE
13. Structure Validation, Analysis, and Presentation Appendix • Table of Nota-
tion • Glossary • Index
Garland Science
November 2009: 800pp: 448 illus, 30 tables, 40 halftones, 408 line drawings
Hb: 978-0-8153-4081-2: £62.00
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structural biology 15
Protein Purification
Philip Bonner, Nottingham Trent University, UK
Protein Purification provides a guide to the major
techniques, including non-affinity absorption tech-
niques, affinity procedures, non-absorption techniques
and methods for monitoring protein purity. There is an
overview of protein strategy and equipment, followed
by discussions and examples of each technique and its
applications.
The basic theory and simple explanations given in Pro-
tein Purification make it an ideal handbook for final year
undergraduates, and postgraduates, who are conducting
research projects. It will also be a useful guide to more
experienced researchers who need a good overview of the techniques and prod-
ucts used in protein purification.
Contents:
1. Protein Purification Strategy and Equipment 2. The Groundwork 3. Non-Affin-
ity Absorption Techniques Used to Purify Proteins 4. Affinity Procedures Used to
Purify Proteins 5. Non-Absorption Techniques for Purifying Proteins 6. Methods
for Monitoring the Purity of Protein Solutions • Appendix 1. The common units
used in biology • Appendix 2. The answers to the exercises • Appendix 3.
Single letter code for amino acids • Appendix 4. The list of suppliers
The Basics
Taylor & Francis
2007: 978-0-415-38511-4: £35.00
E-book available at www.ebookstore.tandf.co.uk
Second Edition
Introduction to Protein Structure
Carl Branden, (deceased), and John Tooze, Cancer Research UK
Introduction to Protein Structure provides an account of
the principles of protein structure, with examples of key
proteins in their biological context generously illus-
trated in full-color to illuminate the structural principles
described in the text. The first few chapters introduce the
general principles of protein structure both for novices
and for non-specialists needing a primer. Subsequent
chapters use specific examples of proteins to show how
they fulfill a wide variety of biological functions. The
book ends with chapters on the experimental approach
to determining and predicting protein structure, as well
as engineering new proteins to modify their functions.
Contents:
PART 1 BASIC STRUCTURAL PRINCIPLES
1. The Building Blocks 2. Motifs of Protein Structure 3. Alpha-Domain Structures
4. Alpha/Beta Structures 5. Beta Structures 6. Folding and Flexibility 7. DNA
Structures
PART 2 STRUCTURE, FUNCTION AND ENGINEERING
8. DNA Recognition in Procaryotes by Helix-Turn-Helix Motifs 9. DNA Recognition
by Eukaryotic Transcription Factors 10. Specific Transcription Factors Belong to a
Few Families 11. An Example of Enzyme Catalysis: Serine Proteinases 12. Mem-
brane Proteins 13. Signal Transduction 14. Fibrous Proteins 15. Recognition of
Foreign Molecules by the Immune System 16. The Structure of Spherical Viruses
17. Prediction, Engineering, and Design of Protein Structures 18. Determination
of Protein Structures
Garland Science
1999: 410pp
Pb: 978-0-8153-2305-1: £45.50
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eBooks are only available to order online
 16 computational biology
Understanding Bioinformatics
Marketa Zvelebil, The Institute of Cancer Research, UK, and Jeremy O. Baum,
Imperial College London, UK
‘…provides an outstanding introduction to the
main bioinformatics problems and tools,
well-balanced between applications to
biological problems and theory behind data
processing methods… an excellent and updated
book for students of Bioinformatics’ Computer
Methods and Programs in Biomedicine
Suitable for advanced undergraduates and post-
graduates, Understanding Bioinformatics provides a
definitive guide to this vibrant and evolving discipline.
The book takes a conceptual approach. It guides the reader from first principles
through to an understanding of the computational techniques and the key algo-
rithms. Understanding Bioinformatics is an invaluable companion for students
from their first encounter with the subject through to more advanced studies.
The book is divided into seven parts, with the opening part introducing the
basics of nucleic acids, proteins and databases. Subsequent parts are divided
into ‘Applications’ and ‘Theory’ Chapters, allowing readers to focus their atten-
tion effectively. In each section, the Applications Chapter provides a fast and
straightforward route to understanding the main concepts and ‘getting started’.
Each of these is then followed by Theory Chapters which give greater detail
and present the underlying mathematics. In Part 2, Sequence Alignments, the
Applications Chapter shows the reader how to get started on producing and
analyzing sequence alignments, and using sequences for database searching,
while the next two chapters look closely at the more advanced techniques and
the mathematical algorithms involved. Part 3 covers evolutionary processes and
shows how bioinformatics can be used to help build phylogenetic trees. Part 4
looks at the characteristics of whole genomes. In Parts 5 and 6 the focus turns
to secondary and tertiary structure – predicting structural conformation and
analysing structure-function relationships. The last part surveys methods of
analyzing data from a set of genes or proteins of an organism and is rounded off
with an overview of systems biology.
The writing style of Understanding Bioinformatics is notable for its clarity, while
the extensive, full-color artwork has been designed to present the key concepts
with simplicity and consistency. Each chapter uses mind-maps and flow diagrams
to give an overview of the conceptual links within each topic.
Contents:
Part 1: Background Basics
1. The Nucleic Acid World 2. Protein Structure 3. Dealing with Databases
Part 2: Sequence Alignments
4. Producing and Analyzing Sequence Alignments 5. Pairwise Sequence Align-
ment and Database Searching 6. Patterns, Profiles, and Multiple Alignments
Part 3: Evolutionary Processes
7. Recovering Evolutionary History 8. Building Phylogenetic Trees
Part 4: Genome Characteristics
9. Revealing Genome Features 10. Gene Detection and Genome Annotation
Part 5: Secondary Structures
11. Obtaining Secondary Structure from Sequence 12. Predicting Secondary
Structures
Part 6: Tertiary Structures
13. Modeling Protein Structure 14. Analyzing Structure-Function Relationships
Part 7: Cells and Organisms
15. Proteome and Gene Expression Analysis 16. Clustering Methods and Statis-
tics 17. Systems Biology
Appendices: Background Theory
Appendix A. Probability, Information, and Bayesian Analysis • Appendix B. Mo-
lecular Energy Functions Appendix • C.Function Optimization
Garland Science
2007: 798pp: 29 tables, 414 line drawings
Pb: 978-0-8153-4024-9: £43.00
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Ecological Models and Dynamics
An Interactive Textbook
Roger Schmitz, University of Notre Dame, IN, USA
Ecological Models and Dynamics uses mathematical
models and computer simulations to study the dynamics
of ecosystems, both natural and in response to distur-
bances. As an electronic ‘pop-up’ textbook, it features
functional software programs deliberately placed to
enhance learning. Links throughout the text jump to
relevant parts of the book and to files in Microsoft Excel®,
Mathcad®, Adobe Acrobat®, and LabVIEW™. Students
can run simulations and models in immediate proximity
to the concepts being explained and can work through
exercises, cross reference concepts, read data tables in
adjoining windows, and navigate the text instantaneously.
Contents:
Note to Reader • Prologue 1. Introduction 2. A single species 3. Competitors
4. Predator-Prey Models 5. Food Chains 6. Competitors Revisited 7. Large Com-
munities 8. A Virtual Ecosystem 9. Spatiotemporal Models and Other Extras
10. Wrapping Up Appendix Mathcad Basics and Examples
Garland Science
February 2009: 300pp in PowerPoint® and PDF: 131 illus
CD-ROM and Booklet: 978-0-8153-4426-1: £27.00
New
Quantitative Understanding of Biosystems
An Introduction to Biophysics
Thomas Nordlund, University of Alabama-Birmingham, USA
This intermediate-level text covers the biophysics of macromolecules and
subcellular structures interactions with light from a quantitative perspective. The
author emphasizes mathematical and computational approaches to study the
properties and physical behavior of biomolecules and nanostructures. He pro-
vides detailed coverage of key principles of statistical mechanics and quantum
effects that are important for biological function, as well as light interactions
with supramolecular structures. The book incorporates learning tools, such as
problem sets, exercises, review material, and learning objectives, and includes
discussions of topics that are often neglected, such as structural hierarchy.
CONTENTS:
1. Introduction to a New World 2. How (Most) Physicists Approach Biophysics 3.
The Math Tools: A First Pass 4. Water 5. Structures: From 0.1 to 10 nm and Larger
6. A First Pass at Supramolecular Structures: Assemblies of Biomolecules 7.
Putting a Cell Together: A Physical Sketch 8. A Quantum Primer 9. Light and Life
10. Photosynthesis 11. Direct Ultraviolet Effects on Biological Systems 12. Me-
chanics and Dynamics 13. Random Walks, Diffusion, and Polymer Conformation
14. A Statistical Physics and Thermodynamics Primer 15. Reactions: A Physical
View 16. Molecular Machines: An Introduction 17. Assembly
CRC Press
February 2011: 583 pp
Hb: 978-1-420-08972-1: £57.99
Garland Science
8 Website: www.garlandscience.com
com
 18 PLANT SCIENCE
Plant Cell Walls
Peter Albersheim, Complex Carbohydrate Research Center, University of Georgia,
USA, Alan Darvill, CCRC, University of Georgia, USA, Keith Roberts emeritus,
John Innes Centre, UK, Ron Sederoff, North Carolina State University, USA, and
Andrew Staehelin emeritus, University of Colorado, USA
Plant cell walls are complex, dynamic cellular
structures essential for plant growth, development,
physiology and adaptation. Plant Cell Walls provides
an in depth and diverse view of the microanatomy,
biosynthesis and molecular physiology of these cellular
structures, both in the life of the plant and in their use
for bioproducts and biofuels.
Plant Cell Walls is a textbook for upper-level un-
dergraduates and graduate students, as well as a
professional-level reference book. Over 350 drawings,
micrographs, and photographs provide visual insight
into the latest research, as well as the uses of plant cell walls in everyday life, and
their applications in biotechnology. Illustrated panels concisely review research
methods and tools; a list of key terms is given at the end of each chapter; and ex-
tensive references organized by concept headings provide readers with guidance
for entry into plant cell wall literature.
Contents:
1. The Cell Wall and Plant Anatomy 2. The Structural Polysaccharides of the Cell
Wall and How They Are Studied 3. Biochemistry of the Cell Wall Molecules 4.
Membrane Systems Involved in Cell Wall Assembly 5. Biosynthesis of Cell Wall
Polymers 6. Architectural Principles and Variations 7. The Cell Wall in Growth and
Development 8. Cell Walls and the Interaction of Plants with Microbes 9. Plant
Cell Walls: A Renewable Material Resource
Garland Science
May 2010: 350pp: 405 illus
Hb: 978-0-8153-1996-2: £60.00
SUPPLEMENT:
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Plant Biochemistry
Caroline Bowsher, University of Manchester, UK, Martin Steer, University
College Dublin, Ireland, and Alyson Tobin, University of St. Andrews, UK
Plant Biochemistry presents each topic from the cel-
lular level to the ecological and environmental levels,
placing it in the context of the whole plant.
Biochemical pathways are represented as route maps,
showing how one reaction follows another. These maps
emphasize the dynamism and flexibility of the plant in
the face of environmental challenges. The unique and
wide-ranging approach of this book emphasizes the
importance of teaching and learning pathways within
the framework of what the pathway does and why it is
needed.
Plant Biochemistry is invaluable to undergraduate students who wish to gain
insight into the relevance of plant biochemistry to humans and animals.
It is an ideal reference text for graduates and researchers.
Contents:
1. Introduction to Plant Biochemistry 2. Approaches to Understanding Metabolic
Pathways 3. Plant Cell Structure 4. Light Reactions of Photosynthesis 5. Photo-
synthetic Carbon Assimilation 6. Respiration 7. Synthesis and Mobilization of
Storage and Structural Carbohydrates 8. Nitrogen and Sulfur Metabolism 9. Lipid
Biosynthesis 10. Alkaloids 11. Phenolics 12. Terpenoids
Garland Science
2008: 500pp: 12 illus, 30 tables, 40 halftones, 280 line drawings
Pb: 978-0-8153-4121-5: £44.00
SUPPLEMENTS:
Figures from the book are available to instructors and students in JPEG format at
www.garlandscience.com/gs_textbooks.asp.
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Plant Biology
Alison M. Smith, John Innes Centre, UK, George Coupland, Max Planck Institute,
Germany, Liam Dolan, John Innes Centre, UK, Nicholas Harberd, University of
Oxford, UK, Jonathan Jones, John Innes Centre, UK, Cathie Martin, John Innes
Centre, UK, Robert Sablowski, John Innes Centre, UK, and Abigail Amey, Science
Editor, London, UK
Plant Biology is a new textbook written for upper-level
undergraduate and graduate students. It is an account
of modern plant science, reflecting recent advances in
genetics and genomics and the excitement they have
created. The book begins with a review of what is
known about the origins of modern-day plants. Next,
the special features of plant genomes and genetics are
explored. Subsequent chapters provide information on
our current understanding of plant cell biology, plant
metabolism, and plant developmental biology, with
the remaining three chapters outlining the interactions
of plants with their environments. The final chapter
discusses the relationship of plants with humans: domestication, agriculture and
crop breeding.
Key Features:
l Modern approach to plant science: provides a comprehensive
coverage of the wealth of new knowledge coming from plant genetics &
molecular biology and the sequencing of Arabidopsis.
l Evolution: includes an account at the molecular biological level of adaptations
that have taken place through the course of plant evolution.
l Growth & Developmental Biology: presents an extensive treatment of plant
development from a genetic and molecular perspective.
l Four color artwork: vividly illustrated with over 1,000 Illustrations, including
- original color line drawings, designed for clarity, simplicity and
consistency
- stunning botanical photography
- microscope and micrograph images gathered from leading plant
laboratories around the world.
l Learning Objectives: each chapter opens with a bullet-point list of learning
objectives, which summarizes the topics to be covered and acts as a revision
checklist.
l Summaries: end-of-chapter summaries provide a broad overview of material
presented allowing the reader to review and assess their understanding of
what they have read.
l Further Reading: each chapter ends with a reference list of research literature
grouped according to topic, guiding readers to significant papers.
Contents:
1. Origins 2. Genomes 3. Cells 4. Metabolism 5. Development 6. Environmental
Signals 7. Environmental Stress 8. Interactions with Other Organisms 9. Domesti-
cation & Agriculture
Garland Science
May 2009: 679pp: 657 illus
Pb: 978-0-8153-4025-6: £42.00
supplement:
Artwork available on Classwire at www.classwire.com/garlandscience
Garland Science
8 Website: www.garlandscience.com

Enzyme Kinetics and Mechanism
Paul F. Cook, University of Oklahoma, USA and W. W. Cleland, University of
Wisconsin-Madison, USA
Enzyme Kinetics and Mechanism is a comprehensive
textbook on steady-state enzyme kinetics. Organized
according to the experimental process, the text covers
kinetic mechanism, relative rates of steps along the
reaction pathway, and chemical mechanism—includ-
ing acid-base chemistry and transition state structure.
Practical examples taken from the literature dem-
onstrate theory throughout. The book also features
numerous general experimental protocols and how-to
explanations for interpreting kinetic data.
Written in clear, accessible language, the book will en-
able graduate students well-versed in biochemistry to understand and describe
data at the fundamental level. Enzymologists and molecular biologists will find
the text a useful reference.
Contents:
1. Nomenclature 2. Introduction to Kinetics 3. Enzyme Assays 4. Derivation of
Initial Velocity Rate Equations and Data Processing 5. Initial Velocity Studies in
the Absence of Added Inhibitors 6. Initial Velocity Studies: Presence of Added
Inhibitors 7. Pre-Steady State and Relaxation Kinetics 8. Isotopic Probes of Kinetic
Mechanism 9. Isotope Effects as a Probe of Mechanism 10. pH Dependence of
Kinetic Parameters and Isotope Effects • Appendix I. King and Altman Patterns
and Distribution Equations • Appendix II. Rate Equations, Definitions of Kinetic
and Inhibition Constants, Haldanes, Distribution Equations and Rate Constants
for a Number of Multireactant Mechanisms
Garland Science
2007: 416pp: 94 illus, 21 tables
Hb: 978-0-8153-4140-6: £45.50
New
Introductory Nanoscience
Physical and Chemical Concepts
Masaru Kuno, at University of Notre Dame, USA
Designed for senior undergraduate and first-year graduate students, Introduc-
tory Nanoscience describes the key quantitative concepts that underlie this new
field. The textbook seeks to answer how we make nanometer-sized objects,
multiply them, track charges in nanoscale systems, and discover new proper-
ties. How do properties of materials change when scaled to nano-size so that
we may predict behavior and functionality? Introductory Nanoscience asks how
nanomaterials may be useful and supplies the quantitative foundation necessary
to understand why they are so fascinating.
key Features:
• Explains fundamental concepts underlying current nanoscience research.
• Over 180 two-color illustrations.
• Solved examples throughout the text.
• End-of-chapter thought problems incorporate further reading.
• References listed for each chapter.
CONTENTS:
1. Introduction 2. Structure 3. Length scales 4. Types of nanostructures 5. Ab-
sorption and emission basics 6. A quantum mechanics review 7. Model quantum
mechanics problems 8. Additional model problems 9. Density of states 10. Bands
11. Time-dependent perturbation theory 12. Interband Transitions 13. Synthesis
14. Characterization 15. Applications 16. Appendix
Garland Science
September 2011: 420 pp: 250 illus
Pb: 978-0-8153-4424-7: £38.00
E-book available at www.ebookstore.tandf.co.uk
SUPPLEMENT:
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CHEMISTRY 19
New
Understanding Nanomaterials
Malkiat Johal, Pomona College, USA
This textbook provides a coherent overview of the fundamental principles
underlying nanomaterials fabrication, as well as a discussion of the characteriza-
tion and application of these materials. The author takes an interdisciplinary
approach, highlighting the theory and tools contributed by chemistry, biology,
physics, medicine, and engineering. Real world examples related to energy, the
environment, and medicine are included throughout the text that underscore
the technological applications.
CONTENTS:
Intermolecular Interactions • Two-Dimensional Nanomaterials • Three-
Dimensional Soft and hard Nanomaterials • Characterization at the Nanoscale •
Photonics and Biophotonics
CRC Press
April 2011: 320 pp
Pb: 978-1-420-07310-2: £38.99
Second Edition
Structure in Protein Chemistry
Jack Kyte, University of California at San Diego, USA
The second edition of Structure in Protein Chemistry
showcases the latest developments and innovations
in the field of protein structure analysis and predic-
tion. The book begins by explaining how proteins are
purified and describes methods for elucidating their
sequences of amino acids and defining their posttrans-
lational modifications. Comprehensive explanations
of crystallography and of noncovalent forces-ionic
interactions, hydrogen bonding, and the hydrophobic
effect-act as a prelude to an exhaustive description of
the atomic details of the structures of proteins. The
resulting understanding of protein molecular structure
forms the basis for discussions of the evolution of proteins, the symmetry of the
oligomeric associations that produce them, and the chemical, mathematical,
and physical basis of the techniques used to study their structures. The latter
include image reconstruction, nuclear magnetic resonance spectroscopy, proton
exchange, optical spectroscopy, electrophoresis, covalent cross-linking, chemical
modification, immunochemistry, hydrodynamics, and the scattering of light,
X-radiation, and neutrons. These procedures are applied to study the folding of
polypeptides and the assembly of oligomers. Biological membranes and their
proteins are also discussed.
Structure in Protein Chemistry, Second Edition, bridges the gap between
introductory biophysical chemistry courses and research literature. It serves as
a comprehensive textbook for advanced undergraduates and graduate students
in biochemistry, biophysics, and structural and molecular biology. Professionals
engaged in chemical, biochemical, and molecular biological research will find it a
useful reference.
Contents:
1. Purification 2. Electronic Structure 3. Sequences of Polymers 4. Crystallo-
graphic Molecular Models 5. Noncovalent Forces 6. Atomic Details 7. Evolution
8. Counting Polypeptides 9. Symmetry 10. Chemical Probes of Structure 11. Im-
munochemical Probes of Structure 12. Physical Measurements of Structure 13.
Folding and Assembly 14. Membranes
Garland Science
2006: 832pp: 700 illus
Hb: 978-0-8153-3867-3: £78.00
8 E-bookstore: www.ebookstore.tandf.co.uk
eBooks are only available to order online
20 Chemistry

NMR for Physical and Biological Scientists

Thomas C. Pochapsky, Brandeis University, USA, and Susan Pochapsky, Bran-
deis University, USA
Nuclear Magnetic Resonance spectroscopy is a dy-
namic way for scientists of all kinds to investigate the
physical, chemical, and biological properties of matter.
Its many applications make it a versatile tool previ-
ously subject to monolithic treatment in reference-
style texts. Based on a course taught for over ten
years at Brandeis University, this is the first textbook
on NMR spectroscopy for a one-semester course or
self-instruction. In keeping with the authors’ efforts
to make it a useful textbook, they have included prob-
lems at the end of each chapter.
The book not only covers the latest developments in the field, such as GOESY
(Gradient Enhanced Overhauser Spectroscopy) and multidimensional NMR,
but includes practical examples using real spectra and associated problem sets.
Assuming the reader has a background of chemistry, physics and calculus, this
textbook will be ideal for graduate students in chemistry and biochemistry, as
well as biology, physics, and biophysics. NMR for Physical and Biological Sci-
entists will also be useful to medical schools, research facilities, and the many
chemical, pharmaceutical, and biotech firms that offer in-house instruction on
NMR spectroscopy.

Contents:
1. What Is Spectroscopy? 2. Elementary Aspects of Nuclear Magnetic Reso-
nance (NMR) 3. Elementary Aspects of NMR II: Fourier Transform NMR 4.
Nuclear Spin Relaxation and the Nuclear Overhauser Effect 5. Classical and
Quantum Descriptions of NMR Experiments in Liquids 6. Density Operator and
Product Operator Descriptions of NMR Experiments in Liquids 7. Homonuclear
Two-Dimensional NMR Experiments and Coherence Selection 8. Heteronuclear
Correlations in NMR 9. Building Blocks for Multidimensional NMR and Special
Considerations for Biological Applications of NMR 10. NMR under Anisotropic
Conditions: NMR in the Solid State and Ordered Fluids 11. Relaxation Revisited:
Dynamic Processes and Paramagnetism 12. Diffusion, Imaging, and Flow
Garland Science
2006: 350pp: 221 illus, 4 tables, 3 halftones, 218 line drawings
Hb: 978-0-8153-4103-1: £57.00

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8 Website: www.garlandscience.com

Third Edition
Biology Today
An Issues Approach
Eli C. Minkoff and Pamela J. Baker, both at Bates College, USA
Biology Today is a truly innovative introductory biology
text. Designed to combine the teaching of biologi-
cal concepts within the context of current societal
issues, Biology Today encourages introductory biology
students to think critically about the role that science
plays in their world. The Third Edition has been revised
and updated, and contains three new chapters: Genetic
Engineering and Genomics, New Infectious Threats, and
Protecting the Biosphere.
Contents:
1. Biology: Science and Ethics 2. Genes, Chromosomes, and DNA 3. Human
Genetics 4. Genetic Engineering and Genomics 5. Evolution 6. Classifying Nature
7. Human Variation 8. Sociobiology 9. The Population Explosion 10. Nutrition
and Health 11. Plants to Feed the World 12. Stem Cells, Cell Division and Cancer
13. The Nervous System and Senses 14. Drugs and Addiction 15. Mind and Body
16. HIV and AIDS 17. New Infectious Threats 18. Biodiversity and Threatened
Habitats 19. Protecting the Biosphere
Garland Science
2003: 768pp
Pb: 978-0-8153-4157-4: £42.50
SUPPLEMENTS:
l The Art of Biology Today, Third Edition CD-ROM: 978-0-8153-4159-8: £41.50
l Overhead Transparencies: 978-0-8153-4160-4: £389.00
l Classwire (course management system and library of teaching resources)
www.classwire.com/garlandscience
l Testbank via Classwire
Third Edition
Biology of Fishes
Quentin Bone, Marine Biological Association of the UK, Plymouth, UK, and Rich-
ard Moore, Coastal Carolina University, USA
The Third Edition of Biology of Fishes is chiefly about
fish as remarkably efficient machines for coping with
the many problems that life in water entails, and looks
at many such special cases.Fishes form the largest
group of vertebrates, with around 20,000 known spe-
cies, and they display a remarkable diversity of size,
shape, internal structure and ecology to cope with
environments ranging from transient puddles to the
abyssal depths of the sea.
Biology of Fishes does not try to cover all aspects
of fish biology, but focuses on the ingenious ways in
which fish have resolved the particular problems that come from living in water,
especially body fluid regulation, locomotion, feeding mechanisms, and sensory
systems. Enough detail is provided for the reader to be able to go on and use
primary research papers. Each chapter has been thoroughly updated and a new
chapter on the immune system has been added.
This is an ideal textbook for students of fish biology and any of the branches of
aquatic biology. Given its skilful combination of breadth and detail, the book also
provides a manageable review of fish biology for experienced biologists.
Contents:
1. Diversity of Fishes 2. Fishes and their Habitats 3. Swimming 4. Buoyancy 5. Gas
Exchange, Blood and the Circulatory System 6. Osmoregulation and Ion Balance
7. Food and Feeding 8. Reproduction and Life Histories 9. Endocrine Systems 10.
Sensory Systems and Communication 11. Nervous System 12. Immune System
13. Behavior and Cognition 14. Fisheries and Aquaculture
Taylor & Francis
2008: 450pp: 14 tables, 280 line drawings
Pb: 978-0-415-37562-7: £43.50
E-book available at www.ebookstore.tandf.co.uk
SUPPLEMENT:
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GENERAL BIOLOGY 21
Second Edition
Stop Working & Start Thinking
Jack Cohen, Science Writer, UK, and Graham Medley, University of Warwick, UK
With the spectacular developments in technology
accompanying and aiding scientific research over the
past few decades, postgraduate students are often
encouraged to focus more on generating data than to
utilize their most sophisticated piece of equipment:
their mind. Stop Working & Start Thinking aims to en-
courage young researchers to think more clearly about
their experiments, from experimental design to data
interpretation. This new edition builds on the success
of the first edition, with new material throughout and a
new chapter on measurement interpretation, including
an examination of cryptic assumptions.
This book is essential reading for postgraduates who wish to put the mastery
back into their M.Sc. and the philosophy back into their PhDs.
Contents:
1. Preamble 2. Introduction 3. Science Like what It is Like 4. How Scientists Work
5. Observations, Examinations and Experiments 6. What are you Measuring? 7.
Thinking About your Measurements 8. Interpreting your Measurements 9. Kinds
of Experiments 10. Here’s the Answer, What’s the Question? 11. Content and
Context 12. Notes for Postgraduate Students 13. Postamble
Taylor & Francis
2005: 150pp: 18 illus, 2 tables
Pb: 978-0-415-36830-8: £15.50
Guide to Publishing a Scientific Paper
Ann M. Körner, Editor and Writer, USA
Guide to Publishing a Scientific Paper provides researchers in every field of the
biological, physical and medical sciences with all the information necessary to
prepare, submit for publication, and revise a scientific paper. The book includes
details of every step in the process that is required for the publication of a
scientific paper, for example. The advice provided conforms to the most up-to-
date specifications and even the seasoned writer will learn how procedures have
changed in recent years, in particular with regard to the electronic submission of
manuscripts.
Contents:
1. The Publication of Scientific Papers 2. Before You Start Writing 3. The Title
Page 4. The Abstract or Summary 5. The Introduction 6. Materials and Methods
7. Human Subjects 8. Results 9. Discussion 10. Acknowledgements 11. Referenc-
es and Notes 12. Figures and Figure legends 13. Tables 14. Supplementary Infor-
mation 15. The First Letter to the Editor of Your Target Journal 16. Submission of
Your Paper 17. Letter from the Editor and Your Response 18. Second Letter to the
Editor with Responses to Reviewers 19. Congratulations, Your Paper Has Been
Accepted! • Appendix. A Note About Writing Applications for Financial Support
Routledge
2008: 106pp
Hb: 978-0-415-45265-6: £80.00
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22 BIOS INSTANT NOTES SERIES – Knowledge You Need in an Instant

— Affordably priced —
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Instant Notes in Instant Notes in New third edition

Analytical Chemistry Human Physiology Instant Notes in
David Kealey, and P J Haines Daniel McLaughlin, Jonathan Stamford, and Neuroscience
2002: 352pp David White Alan Longstaff
Pb: 978-1-85996-189-6: £20.00 2006: 410pp 2011: 400pp
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Second Edition
Instant Notes in New third edition Second Edition
Animal Biology Instant Notes in Instant Notes in
Richard Jurd Immunology Organic Chemistry
2003: 312pp Peter Lydyard, Alex Whelan, and Michael Fanger Graham Patrick
Pb: 978-1-85996-325-8: £20.00 2011: 340pp 2003: 328pp
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New Fourth edition
Instant Notes in Second Edition Instant Notes in
Biochemistry Instant Notes in Physical Chemistry
David Hames, and Nigel Hooper Inorganic Chemistry Gavin Whittaker, Andy Mount, and Matthew Heal
2011: 467pp Tony Cox 2000: 296pp
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Second Edition Instant Notes in
Instant Notes in Instant Notes in Physiological Psychology
Bioinformatics Mathematics and Statistics Hugh Wagner, and Kevin Silber
Charlie Hodgman, Andrew French, and for Life Scientists 2004: 288pp
David Westhead Aulay MacKenzie Pb: 978-1-85996-203-9: £20.00
August 2009: 300pp 2005: 176pp
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Instant Notes in
Second Edition Instant Notes in Plant Biology
Instant Notes in Medical Microbiology Andrew Lack, and David Evans
Chemistry for Biologists Will Irving, Tim Boswell, and Dlawer Ala’Aldeen 2005: 350pp
J. Fisher, and J.R.P. Arnold 2005: 344pp Pb: 978-0-415-35643-5: £20.00
2003: 288pp Pb: 978-1-85996-254-1: £20.00
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Instant Notes in Medicinal Chemistry I.P. Christensen, Hugh Wagner, and
Cognitive Psychology Graham Patrick Sebastian Halliday
Jackie Andrade, and Jon May 2001: 288pp 2000: 328pp
2003: 256pp Pb: 978-1-85996-207-7: £20.00 Pb: 978-1-85996-097-4: £20.00
Pb: 978-1-85996-223-7: £20.00
New Fourth edition Instant Notes in
Instant Notes in Instant Notes in Sport and Exercise
Developmental Biology Microbiology Biomechanics
Richard Twyman Simon Baker, Jane Nicklin, and Caroline Griffiths Paul Grimshaw, Neil Fowler, Adrian Lees, and
2000: 464pp 2011: 341pp Adrian Burden
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Second Edition Third Edition
Instant Notes in Instant Notes in Instant Notes in
Ecology Molecular Biology Sport and Exercise
Aulay MacKenzie, Andy Ball, and Sonia Virdee Phil Turner, Alexander McLennan, Andy Bates, and Physiology
2001: 352pp Michael White Karen Birch, Keith George, and Don McLaren
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Third Edition
Instant Notes in Instant Notes in Instant Notes in
Genetics Motor Control, Learning Sport and Exercise
Hugh Fletcher, Ivor Hickey, and Paul Winter and Development Psychology
2006: 379pp Andrea Utley, and Sarah Astill Dave Shaw, Trish Gorely, and Rod Corban
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 THE BASICS SERIES, BIOS ADVANCED METHODS / TEXTS SERIES
the basics series
Second Edition
Animal Cell Culture and
Technology
Mike Butler, University of Manitoba, Canada
Describes the basic requirements for establishing
and maintaining cell cultures both in the laboratory
and in large-scale operations.
2003: 256pp
Pb: 978-1-85996-049-3: £35.00
Measuring Gene Expression
Matthew Avison, University of Bristol, UK
Measuring Gene Expression is an all-in-one
introduction to the main methods of measuring
gene expression, including RT-PCR, differential
display, RNA interference, reporter genes,
microarrays, and proteomics, as well as a section on
RNA isolation and analysis.
2006: 328pp
Pb: 978-0-415-37472-9: £35.00
Second Edition
PCR
Mike McPherson, University of Leeds, UK and
Simon Møller, University of Stavanger, Norway
Provides an introductory text for undergraduate
students, graduate students and scientists who want
to understand and use PCR for experimental
purposes.
2006: 292pp
Pb: 978-0-415-35547-6: £35.00
Plant Cell Culture
David Evans, Oxford Brookes University, UK, Julian
Coleman, Institute of Arable Crops Research, UK,
and Anne Kearns, Oxford Brookes University, UK
Plant Cell Culture provides the reader with a concise
overview of numerous variant techniques, including
basic plant biology for cell culture, basic sterile
technique and media preparation, specific
techniques for various plant cell and tissue types
including applications, tissue culture in agriculture,
horticulture and forestry and culture for genetic
engineering and biotechnology.
2003: 208pp
Pb: 978-1-85996-320-3: £35.00
Protein Purification
Philip L.R. Bonner, Nottingham Trent University, UK
Protein Purification provides a guide to the major
techniques, including non-affinity absorption
techniques, affinity procedures, non-absorption
techniques and methods for monitoring protein
purity.
2007: 230pp
Pb: 978-0-415-38511-4: £35.00
Working With DNA
Stan Metzenberg, California State University
Northridge, USA
Working with DNA is a guide to the materials and
methods that are used in the recombinant DNA
laboratory and is designed to help the novice
understand how specific laboratory techniques
work, but also has sections that may stimulate the
thinking of experienced researchers.
2007: 414pp
Pb: 978-0-415-37464-4: £35.00
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23
BIOS Advanced Methods Series BIOS Advanced Texts Series
DNA Microarrays Bioinformatics
Edited by Ulrike Nuber, Lund Strategic Research Genes, Proteins and Computers
Center for Stem Cell Biology and Cell Therapy,
Sweden
Edited by Christine Orengo and David Jones both at
University College London, UK, and Janet Thornton,
Introduces all up-to-date microarray platforms and European Bioinformatics Institute, UK
their various applications. It is written for scientists Bioinformatics covers both the more traditional
who are entering the field of DNA microarrays as approaches to bioinformatics, including gene and
well as those already familiar with the technology, protein sequence analysis and structure prediction,
but interested in new applications and methods. and more recent technologies such data mining
2005: 299pp of transcriptomic and proteomic data to provide
Pb: 978-0-415-35866-8: £45.00 insights on cellular mechanisms and the causes of
disease.
Gene Targeting and Embryonic 2002: 320pp
Stem Cells Pb: 978-1-85996-054-7: £45.00
Jim Mcwhir, and Alison Thomson, both at The
Roslin Institute, UK Second Edition
Provides details on how to culture, transfect and
differentiate established cell lines, and how to
Molecular Biology of Cancer
Fiona Macdonald, Birmingham Womens Hospital
isolate new cell lines. Gene targeting experiments
NHS Trust, UK, Christopher Ford, Kuwait University,
are described for a number of cell types, and include
Kuwait, and Alan Casson, Queen Elizabeth Health
protocols for gene-targeting vendors, DNA
Science Centre, Canada
transfection and RNA interface.
Molecular Biology of Cancer, Second Edition has
2004: 216pp
been extensively revised and covers heredity cancer,
Pb: 978-1-85996-360-9: £45.00
microarray technology and increased study of
Gene Transfer to Animal Cells childhood cancers.
Richard Twyman, University of York, UK 2004: 269pp
Pb: 978-1-85996-247-3: £45.00
Describes the principles behind gene transfer
technologies, how gene expression is controlled in
animal cells and how advanced strategies can be
Molecular Plant Pathology
Matthew Dickinson, University of Nottingham, UK
used to add, exchange or delete sequences from
animal genomes in a conditional manner. Molecular Plant Pathology addresses the underlying
molecular principles of plant/pathogen interactions,
2004: 256pp
in a readily accessible textbook format.
Pb: 978-1-85996-204-6: £45.00
2003: 244pp
Molecular Microbial Ecology Pb: 978-1-85996-044-8: £45.00
Edited by Mark Osborn, and Cindy Smith, both at
University of Sheffield, UK Molecular Toxicology
Nick Plant, University of Surrey, UK
Provides a comprehensive guide to the recent
Molecular Toxicology is a concise introduction to the
revolution in the study of microorganisms in the
subject, taking the reader through the theoretical
environment.
principles of toxicology followed by specific
2005: 256pp
examples.
Pb: 978-1-85996-283-1: £45.00
2003: 150pp
Real-time PCR Pb: 978-1-85996-345-6: £45.00
Edited by Tevfik Dorak, Humigen LLC, USA
Provides the basic principles, explains how they are
Principles of Proteomics
Richard Twyman, University of York, UK
exploited to run a real-time PCR assay, how the
Principles of Proteomics is designed specifically to
assays are run, and where these assays are
informative in real life. explain the different stages of proteomic analysis,
their complexities and their jargon to students and
2006: 333pp
researchers in a non-technical overview of the field.
Pb: 978-0-415-37734-8: £45.00
2004: 266pp
RNAi Pb: 978-1-85996-273-2: £45.00
Edited by Martin Latterich, Form Consulting, Inc.,
California, USA
Covers the basic concepts and mechanisms of RNAi,
transfection of cells with siRNAs, the design and
validation of RNAi reagents, RNAi techniques in
different organisms, large-scale RNAi screening,
applications of RNAi in drug discovery, and potential
uses of RNAi as a therapeutic agent.
2007: 158pp
Pb: 978-0-415-40950-6: £45.00
The Basics are ideal introductions to new techniques in the laboratory.
Advanced Methods/Texts are invaluable reference texts for advanced
undergraduate and graduate students and established researchers.
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 24 Title index

A Instant Notes in Cognitive Psychology. . . . . . 22 Molecular Plant Pathology. . . . . . . . . . . 23

Animal Cell Culture and Technology . . . . . . . 23 Instant Notes in Developemental Biology. . . . 22 Molecular Toxicology. . . . . . . . . . . . . 23
Instant Notes in Ecology.. . . . . . . . . . . 22 NEW Mucosal Immunology. . . . . . . . . . 13
B Instant Notes in Genetics.. . . . . . . . . . . 22
Bioinformatics . . . . . . . . . . . . . . . . 23 Instant Notes in Human Physiology . . . . . . . 22 N
Biology of Cancer, The . . . . . . . . . . . . . 5 NEW Instant Notes in Immunology . . . . . 22, 13 NMR for Physical and Biological Scientists. . . . 20
Biology of Disease. . . . . . . . . . . . . . 11 Instant Notes in Inorganic Chemistry. . . . . . 22
Biology of Fishes. . . . . . . . . . . . . . . 21 Instant Notes in Mathematics and Statistics for Life O
Scientists . . . . . . . . . . . . . . . . . . 22
Biology Today. . . . . . . . . . . . . . . . 21
NEW Instant Notes in Medical Microbiology.. . . 22
P
Biomolecular Crystallography. . . . . . . . . 15 PCR. . . . . . . . . . . . . . . . . . . . 23
Instant Notes in Medicinal Chemistry.. . . . . . 22
Physical Biology of the Cell. . . . . . . . . . . 4
C Instant Notes in Microbiology. . . . . . . . . 22, 9
Plant Biochemistry . . . . . . . . . . . . . . 18
NEW Case Studies in Immunology. . . . . . . 12 Instant Notes in Molecular Biology.. . . . . . . 25
Instant Notes in Motor Control, Learning and Plant Biology. . . . . . . . . . . . . . . . 18
Case Studies in Infectious Disease . . . . . . . 11
Development. . . . . . . . . . . . . . . . 22 Plant Cell Culture. . . . . . . . . . . . . . . 23
Cell Movements . . . . . . . . . . . . . . . 4
NEW Instant Notes in Neuroscience. . . . . . 22, 2 Plant Cell Walls. . . . . . . . . . . . . . . 18
Cellular Signal Processing. . . . . . . . . . . . 3
Instant Notes in Organic Chemistry. . . . . . . . 22 Principles of Proteomics. . . . . . . . . . . . 23
D Instant Notes in Physical Chemistry.. . . . . . . 22 Protein Purification . . . . . . . . . . . . 15, 23
DNA Microarrays . . . . . . . . . . . . . . . 23 Instant Notes in Physiological Psychology. . . . 22 Protozoa and Human Disease. . . . . . . . . 11
Instant Notes in Plant Biology . . . . . . . . . 22
E Instant Notes in Psychology. . . . . . . . . . . 22
Q
Ecological Models and Dynamics . . . . . . . . 16 Instant Notes in Sport and Exercise Biomechanics..22 NEW Quantitive Understanding of Biosystems. . 16
Emerging Protozoan Pathogens . . . . . . . . 11 Instant Notes in Sport and Exercise Physiology. . 22
Enzyme Kinetics and Mechanism. . . . . . . . 19 Instant Notes in Sport and Exercise Psychology. 22
R
Real-time PCR . . . . . . . . . . . . . . . . 23
Essential Cell Biology . . . . . . . . . . . . . 1 NEW Introductory Nanoscience. . . . . . . . 19
RNAI. . . . . . . . . . . . . . . . . . . 8, 23
NEW Introduction To Genetics: A Molecular
F Approach. . . . . . . . . . . . . . . . . . 6 S
NEW Fields, Forces, and Flows in Biological Systems.14 Introduction to Protein Structure . . . . . . . . 15 Statistical Genetics. . . . . . . . . . . . . . 7
G J Stop Working & Start Thinking . . . . . . . . . 21
Gene Cloning. . . . . . . . . . . . . . . . . 7 Structure in Protein Chemistry. . . . . . . . . 19
NEW Janeway’s Immunobiology. . . . . . . . . 12
Gene Control. . . . . . . . . . . . . . . . . 7
Gene Targeting and Embryonic Stem Cells . . . . 23 K T
Gene Transfer to Animal Cells . . . . . . . . . 23
Genome Duplication. . . . . . . . . . . . . . 6 L U
Understanding Bioinformatics.. . . . . . . . . 16
Genomes 3. . . . . . . . . . . . . . . . . . 8 Living in a Microbial World . . . . . . . . . . 10
NEW Understanding Nano Materials. . . . . . 19
H M V
NEW How Proteins Work . . . . . . . . . . . 14 NEW Marine Microbiology . . . . . . . . . . 10
NEW Viruses . . . . . . . . . . . . . . . . 10
Human Evolutionary Genetics. . . . . . . . . . 8 Mathematics for Biological Scientists. . . . . . . 4
Human Molecular Genetics. . . . . . . . . . . 6 Measuring Gene Expression . . . . . . . . . . 23 W
Microbiology: A Clinical Approach. . . . . . . . 9 Working with DNA. . . . . . . . . . . . . . 8, 23
I Molecular Biology of Cancer. . . . . . . . . . 23
Immune System, The . . . . . . . . . . . . . 13 Molecular Biology of the Cell . . . . . . . . . . 1 X
Instant Notes in Analytical Chemistry . . . . . . 22 Molecular Biology of the Cell - Reference Edition. . 2
Instant Notes in Animal Biology . . . . . . . . 22 Molecular Biology of the Cell - The Problems Book. .2 Y
NEW Instant Notes in Biochemistry. . . . . . 22, 2 Molecular Driving Forces . . . . . . . . . . . . 3
Instant Notes in Chemistry for Biologists.. . . . 22 Molecular Microbial Ecology . . . . . . . . . . 23 Z

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 author index

A Hames, David.. . . . . . . . . . . . . . . . 22 O
Ahmed, Nessar. . . . . . . . . . . . . . . . 11 Harberd, Nicholas. . . . . . . . . . . . . . 18 Osborn, Mark. . . . . . . . . . . . . . . . 23
Aitken, Mike. . . . . . . . . . . . . . . . . 4 Harper, David R. . . . . . . . . . . . . . . 10 Orengo, Christine . . . . . . . . . . . . . . 23
Ala’Aldeen, Dlawer . . . . . . . . . . . . . . 22 Heal, Matthew. . . . . . . . . . . . . . . . 22
Albersheim, Peter. . . . . . . . . . . . . . 18 Hickey, Ivor .. . . . . . . . . . . . . . . . . 22 P
Alberts, Bruce . . . . . . . . . . . . . . . 1, 2 Hladky, Stephen . . . . . . . . . . . . . . . . 4 Parham, Peter. . . . . . . . . . . . . . . . 13
Amey, Abigail . . . . . . . . . . . . . . . . 18 Hodgman, Charlie. . . . . . . . . . . . . . 22 Patrick, Graham. . . . . . . . . . . . . . . 22
Andrade, Jackie . . . . . . . . . . . . . . . 22 Hofkin, Bruce. . . . . . . . . . . . . . . . 10 Phillips, Rob . . . . . . . . . . . . . . . . . 4
Arnold, J. R. P. . . . . . . . . . . . . . . . . 22 Holton, John. . . . . . . . . . . . . . . . . 11 Plant, Nick . . . . . . . . . . . . . . . . . 23
Astill, Sarah . . . . . . . . . . . . . . . . . 22 Hooper, Nigel. . . . . . . . . . . . . . . . 22 Pochapsky, Susan . . . . . . . . . . . . . . 20
Avison, Matthew . . . . . . . . . . . . . . . 23 Hopkin, Karen . . . . . . . . . . . . . . . . 1 Pochapsky, Thomas C. . . . . . . . . . . . . 20
Hunt, Tim . . . . . . . . . . . . . . . . . . 3 Porakishvili, Nino. . . . . . . . . . . . . . 11
B Hurles, Matthew .. . . . . . . . . . . . . . . 8 Posthuma, Danielle. . . . . . . . . . . . . . 7
Baker, Pamela J . . . . . . . . . . . . . . . 21
Baker, Simon . . . . . . . . . . . . . . . 9, 22 I Q
Ball, Andy . . . . . . . . . . . . . . . . . . 22 Irving, Will. . . . . . . . . . . . . . . . 11, 22
Bates, Andy . . . . . . . . . . . . . . . . . 22 R
Baum, Jeremy O. . . . . . . . . . . . . . . . 16 J Raff, Martin . . . . . . . . . . . . . . . . 1, 2
Bell, Stephen. . . . . . . . . . . . . . . . . 6 Jobling, Mark. . . . . . . . . . . . . . . . . 8 Read, Andrew . . . . . . . . . . . . . . . . 6
Ben-Tal, Nir . . . . . . . . . . . . . . . . . 14 Johal, Malkiat . . . . . . . . . . . . . . . . 19 Roberts, Keith . . . . . . . . . . . . . . 1, 2, 18
Birch, Karen. . . . . . . . . . . . . . . . . 22 Johnson, Alexander. . . . . . . . . . . . . 1, 2 Rupp, Bernhard. . . . . . . . . . . . . . . . 18
Blumberg, Richard S. . . . . . . . . . . . . . 13 Jones, David . . . . . . . . . . . . . . . . . 23
Bone, Quentin . . . . . . . . . . . . . . . . 21 Jones, Jonathan. . . . . . . . . . . . . . . 18 S
Bonner, Philip L. R. . . . . . . . . . . . . 15, 23 Jurd, Richard . . . . . . . . . . . . . . . . 22 Sablowski, Robert. . . . . . . . . . . . . . 18
Boswell, Tim. . . . . . . . . . . . . . . . . 22 Schmitz, Roger. . . . . . . . . . . . . . . . 16
Bowsher, Caroline. . . . . . . . . . . . . . . 18
K Sederoff, Ron. . . . . . . . . . . . . . . . 18
Kealey, David. . . . . . . . . . . . . . . . 22 Shaw, Dave.. . . . . . . . . . . . . . . . . 22
Branden, Carl.. . . . . . . . . . . . . . . . 15
Kearns, Anne. . . . . . . . . . . . . . . . 23 Silber, Kevin. . . . . . . . . . . . . . . . . 22
Bray, Dennis . . . . . . . . . . . . . . . . 1, 4
Kessel, Amit . . . . . . . . . . . . . . . . . 14 Smith, Alison M. . . . . . . . . . . . . . . . 18
Broadhurst, Bill. . . . . . . . . . . . . . . . 4
Khan, Naveed Ahmed.. . . . . . . . . . . 11, 22 Smith, Cindy. . . . . . . . . . . . . . . . . 23
Bromberg, Sarina . . . . . . . . . . . . . . . 3
Klingmüller, Ursula . . . . . . . . . . . . . . 3 Smith, Chris. . . . . . . . . . . . . . . . . 11
Brown, T. A.. . . . . . . . . . . . . . . . . 8
Kondev, Jane . . . . . . . . . . . . . . . . . 4 Smith, Phillip D. . . . . . . . . . . . . . . . 13
Burden, Adrian . . . . . . . . . . . . . . . 22
Körner, Ann M. . . . . . . . . . . . . . . . 21 Staehelin, Andrew.. . . . . . . . . . . . . . 18
Butler, Mike. . . . . . . . . . . . . . . . . 23
Kuno, Masaru . . . . . . . . . . . . . . . . 19 Stamford, Jonathan. . . . . . . . . . . . . . 22
C Kyte, Jack. . . . . . . . . . . . . . . . . . 19 Steer, Martin. . . . . . . . . . . . . . . . 18
Casson, Alan. . . . . . . . . . . . . . . . . 23 Strachan, Tom. . . . . . . . . . . . . . . . 6
Christensen, I. P. . . . . . . . . . . . . . . . 22
L Strelkauskas, Anthony . . . . . . . . . . . . . 9
Lack, Andrew. . . . . . . . . . . . . . . . 22 Strelkauskas, Jennifer . . . . . . . . . . . . . 9
Cleland, W. W.. . . . . . . . . . . . . . . . 19
Latchman, David. . . . . . . . . . . . . . . 7
Cohen, Jack . . . . . . . . . . . . . . . . 21
Cole, Michael. . . . . . . . . . . . . . . . 11
Latterich, Martin. . . . . . . . . . . . . . . 23 T
Lees, Adrian. . . . . . . . . . . . . . . . . 22 Theriot, Julie . . . . . . . . . . . . . . . . . 4
Coleman, Julian . . . . . . . . . . . . . . . 23
Lewis, Julian . . . . . . . . . . . . . . . . 1, 2 Thomson, Alison. . . . . . . . . . . . . . . 23
Cook, Paul F.. . . . . . . . . . . . . . . . . 19
Lewis, Ricki. . . . . . . . . . . . . . . . . . 7 Thornton, Janet . . . . . . . . . . . . . . . 23
Corban, Rod . . . . . . . . . . . . . . . . . 22
Lodge, Julia . . . . . . . . . . . . . . . . . 7 Tobin, Alyson. . . . . . . . . . . . . . . . . 18
Coupland, George. . . . . . . . . . . . . . 18
Longstaff, Alan. . . . . . . . . . . . . . . . 22 Tooze, John . . . . . . . . . . . . . . . . . 15
Cox, Tony . . . . . . . . . . . . . . . . . 22
Lund, Peter. . . . . . . . . . . . . . . . . . 7 Turner, Phil. . . . . . . . . . . . . . . . . 22
D Lydyard, Peter. . . . . . . . . . . . . . 11, 22 Twyman, Richard. . . . . . . . . . . . . 22, 23
Darvill, Alan . . . . . . . . . . . . . . . . . 18 Tyler-Smith, Chris . . . . . . . . . . . . . . . 8
Dawson, Maureen .. . . . . . . . . . . . . . 11
M
DePamphilis, Melvin .. . . . . . . . . . . . . 6
MacDonald, Fiona. . . . . . . . . . . . . . 23 U
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