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    Reductase Inhibitors E.G. Finasteride

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    Evie Ricky
    Benign Prostatic Hyperplasia (BPH) is a common condition in men over 40 where the prostate gland enlarges without malignancy, causing urinary symptoms like frequent urination and weak urine stream. Diagnosis involves urinalysis, prostate exam, and ruling out prostate cancer. Treatment options include lifestyle changes, medications like alpha blockers, and surgery such as transurethral resection of the prostate (TURP). Complications of TURP can include bleeding, infection, and a rare but serious condition called TUR syndrome where irrigation fluid enters the bloodstream.

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    Reductase Inhibitors E.G. Finasteride

    Uploaded by

    Evie Ricky
    40 views1 page
    Benign Prostatic Hyperplasia (BPH) is a common condition in men over 40 where the prostate gland enlarges without malignancy, causing urinary symptoms like frequent urination and weak urine stream. Diagnosis involves urinalysis, prostate exam, and ruling out prostate cancer. Treatment options include lifestyle changes, medications like alpha blockers, and surgery such as transurethral resection of the prostate (TURP). Complications of TURP can include bleeding, infection, and a rare but serious condition called TUR syndrome where irrigation fluid enters the bloodstream.

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    BPH

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    Benign Prostatic Hyperplasia (BPH) is a common condition in men over 40 where the prostate gland enlarges without malignancy, causing urinary symptoms like frequent urination and weak urine stream. Diagnosis involves urinalysis, prostate exam, and ruling out prostate cancer. Treatment options include lifestyle changes, medications like alpha blockers, and surgery such as transurethral resection of the prostate (TURP). Complications of TURP can include bleeding, infection, and a rare but serious condition called TUR syndrome where irrigation fluid enters the bloodstream.

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    40 views1 page

    Reductase Inhibitors E.G. Finasteride

    Uploaded by

    Evie Ricky
    Benign Prostatic Hyperplasia (BPH) is a common condition in men over 40 where the prostate gland enlarges without malignancy, causing urinary symptoms like frequent urination and weak urine stream. Diagnosis involves urinalysis, prostate exam, and ruling out prostate cancer. Treatment options include lifestyle changes, medications like alpha blockers, and surgery such as transurethral resection of the prostate (TURP). Complications of TURP can include bleeding, infection, and a rare but serious condition called TUR syndrome where irrigation fluid enters the bloodstream.

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    Benign Prostatic Hyperplasia (BPH)

    *TUR syndrome: uncommon but serious;


    Def: sterile irrigation (contains low Na+) used to
    Increase in size of the prostate gland clean area during prostate surgery can
    without malignancy cause hyponatraemia if solution enters the
    bloodstream; S&S: nausea, vomiting,
    Epidem: fatigue, cerebral oedema, seizures; Ix:
    Common; ↑ with age Blood tests to determine severity; Rx: Fluid
    24% (40-64 yrs); 40% (>64 yrs) restriction, IV fluid, salt administration

    S&S:
    Nocturia, frequency, terminal dribbling, Prostate Cancer
    weak stream, strangury, hesitancy,
    incontinence, dysuria, straining, haematuria Def:
    Mostly carcinomas arising in peripheral
    Ix: zone of the prostate
    Urine flow meter, blood tests, U&E, MSU,
    PSA, renal USS, PR exam, cystoscopy Epidem:
    2nd commonest male malignancy; ↑ with
    Rx: age; 50 per 100 000
    Lifestyle: ↓ fluid intake before bedtime, ↓
    alcohol, ↓ caffeine S&S:
    Med: α-blockers e.g. tamsulosin, alfuzosin, Asymptomatic or nocturia, hesitancy, poor
    doxazosin (SE: drowsiness, depression, stream, terminal dribbling, obstruction
    BP↓, dry mouth, weight ↑ etc.); 5α-
    reductase inhibitors e.g. finasteride, Ix:
    dutasteride (SE: impotence, libido ↓) PSA, transrectal USS & biopsy, bone x-
    Thermotherapy – radiofrequency waves rays, bone scan, CT/MRI
    Surgery: TURP (gold standard), TUIP,
    TULIP, open prostatectomy Rx:
    Radical prostatectomy, chemotherapy,
    TURP: radiotherapy (brachytherapy), hormone
    30-60 mins therapy, goserelin (gonadotropin-releasing
    Under epidural or general anaesthesia. analogues)
    A resectoscope is inserted into urethra
    towards the prostate.
    Heated wire of the resectoscope cuts away Bladder Tumours
    parts of prostate that cause problem.
    Pieces of prostate are flushed away with Def:
    water pumped through the resectoscope. Uncontrolled growth of the cells lining the
    bladder wall
    *Risks: accidental damage to bladder,
    urethra or nerves leading to retrograde Epidem:
    ejaculation, urinary incontinence, urethra ~1:5000/yr
    strictures & impotence ♂:♀ ≈ 4:1

    *Complications: bleeding, clot retention,


    infection, TUR syndrome

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