r7104 - Pharmaceutical Organic Chemistry-I

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Code :R7104 R7

B.Pharmacy I Year Supplementary Examinations, May 2011


PHARMACEUTICAL ORGANIC CHEMISTRY-I
Time: 3 hours Max Marks: 80
Answer any FIVE questions
All questions carry equal marks
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1. Discuss the Electronic effects in organic molecules.

2. Explain nomenclature and isomerism of aliphatic and alicyclic compounds.

3. (a) Discuss in detail aromaticity in organic compounds.


(b) Explain reaction mechanism of Birch reduction.
1 2
4. Explain SN and SN reaction mechanism.

5. Give reaction mechanism of following:

(a) Reimer Tiemann reaction.


(b) Williamson’s synthesis.

6. Show detail reaction mechanism of the following:

(a) Aldol condensation.


(b) Reformatsky reaction.

7. (a) Explain two important methods of preparation of carboxylic acid.


(b) Write note on Hofmann’s degradation of amides.

8. Write short note on the following:

(a) systhesis of nitrites and isonitrites


(b) diazotisation
(c) acidity of nitro compounds

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