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  • Blood Products For Transfusion

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    Fize Castro
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    Blood consists of plasma and corpuscles. There are four main blood groups - A, B, AB, and O - determined by the presence or absence of antigens and antibodies. For safe transfusion, the donor's blood antigens must match the recipient's plasma antibodies to avoid agglutination and clumping of red blood cells, which can be fatal. People with blood type O are universal donors as their blood lacks antigens, while those with type AB are universal recipients as they lack antibodies.

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    Blood Products for Transfusion

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    Blood consists of plasma and corpuscles. There are four main blood groups - A, B, AB, and O - determined by the presence or absence of antigens and antibodies. For safe transfusion, the donor's blood antigens must match the recipient's plasma antibodies to avoid agglutination and clumping of red blood cells, which can be fatal. People with blood type O are universal donors as their blood lacks antigens, while those with type AB are universal recipients as they lack antibodies.

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    9 views2 pages

    Blood Products For Transfusion

    Uploaded by

    Fize Castro
    Blood consists of plasma and corpuscles. There are four main blood groups - A, B, AB, and O - determined by the presence or absence of antigens and antibodies. For safe transfusion, the donor's blood antigens must match the recipient's plasma antibodies to avoid agglutination and clumping of red blood cells, which can be fatal. People with blood type O are universal donors as their blood lacks antigens, while those with type AB are universal recipients as they lack antibodies.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as DOC, PDF, TXT or read online from Scribd
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    Blood Products for Transfusion

    Introduction to Blood: An average human being has about 5.5 litres of blood in the body. About 55 percent of the blood consists of fluid called plasma and remaining 45 percent consists of solid particles called corpuscles. Blood moves from the heart through the arteries to all parts of the body and then back to the heart through veins. The study of blood is called haematology and its formation is called haemopoiesis. Let us discuss the blood products for transfusion in detail. Before this, we should have a knowledge of Blood Groups.

    Blood Products for Transfusion (blood Groups):


    On the basis of proteins that are present in blood, a system of blood groups known as ABO system having four blood groups is recognized in thehuman blood. - Group A with corpuscle factor A and plasma factor b (blood group A has antigen A and antibody b. - Group B with corpuscle factor B and plasma factor a (Blood Group B has antigen B and antibody a) - Group AB with both A and B corpuscle factors but no plasma factor (Blood group AB has both A and B antigens but no antibody). - Group O has no corpuscle factor but both plasma factors (Blood Group O has no antigen but both antibodies)

    Blood Products for Transfusion

    Knowledge of blood groups is essential for safe blood transfusion so that corpuscle factor (antigen) of the donor's blood should be matched with the plasma factor (antibodies) of the recipient. The antigens of the donor's blood can react with antibodies of the recipient's blood and cause clumping of RBCs. Thus, antigen A present in the RBCs of blood group A individuals reacts with antibodies of plasma of blood group B individuals and vice versa. This phenomenon is known as agglutination. Agglutination may cause serious consequences and even prove fatal. However, the RBCs of blood group O individuals lack antigens and are not clumped by antibodies present in the serum of recipient's blood. It means blood group ) can be given to persons with blood group O, A, B, or AB. Hence persons with blood group O are called universal donors. However, persons with blood group AB lack antibodies in their plasma, so they can receive blood from A, B, O, or AB blood groups. Such persons are called universal recipients.

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