Code No: RR322305 Set No.

1
III B.Tech II Semester Supplimentary Examinations, Aug/Sep 2008
IMMUNOLOGY
(Bio-Technology)
Time: 3 hours Max Marks: 80
Answer any FIVE Questions
All Questions carry equal marks
⋆⋆⋆⋆⋆

1. Explain any two [8+8]

(a) adjuvants.
(b) complement.
(c) MHC.
(d) T cells.

2. Define immunoglobulin and explain about its structure and function. [3+8+5]

3. (a) What is the diagnostic method of shigella and list out the other applications
of it? [5+3]
(b) Explain the diagnostic method of diphtheria and list its other applications.
[5+3]

4. Define a cytokines and explain about their role in immune response, and its prod-
ucts. [2+10+4]

5. Define hybridoma and explain monoclonal antibody production? [3+13]

6. Explain the overview of signal transduction during T-cell activation? [16]

7. Discuss about the purified macromolecules as vaccines? [16]

8. Describe different types of systemic autoimmune diseases and explain in detail

about anyone of them? [4+12]

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Code No: RR322305 Set No. 2
III B.Tech II Semester Supplimentary Examinations, Aug/Sep 2008
IMMUNOLOGY
(Bio-Technology)
Time: 3 hours Max Marks: 80
Answer any FIVE Questions
All Questions carry equal marks
⋆⋆⋆⋆⋆

1. What is meant by Hematopoiesis and explain its role in the generation of various
immune cells. [3+13]

2. Write a short notes on :

(a) antigen receptors. [8+8]

(b) VL regions.
(c) VH regions.
(d) Hinge region.

3. What are monoclonal antibodies and explain its importance? [12+4]

4. What a short notes on: [8+8]

(a) interferons.
(b) interlevkines.
(c) Tc cells.
(d) TH cells.

5. Give an account on immunosuppressive therapy? [16]

6. Give an account on the precipitation reactions of antigens with antibodies? [16]

7. Give an account on the mediators of type I hypersensitivity? [16]

8. What is meant by HLA & explain HLA typing? [8+8]

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Code No: RR322305 Set No. 3
III B.Tech II Semester Supplimentary Examinations, Aug/Sep 2008
IMMUNOLOGY
(Bio-Technology)
Time: 3 hours Max Marks: 80
Answer any FIVE Questions
All Questions carry equal marks
⋆⋆⋆⋆⋆

1. What is meant by complement and explain in detail the different pathways of

complement system? [3+13]

2. Explain the process involved in the activation of B cells. [16]

3. What are monoclonal antibodies and explain its importance? [12+4]

4. What are interferons and explain about various types of cytokines . [8+8]

5. (a) Describe the process for culturing of the stem cells? [8+8]
(b) Explain the role of stem cells in controlling Immunodeficiency?

6. Explain different types of forces that causes antigen - antibody interactions? [16]

7. Define hypersensitivity & discuss different types of hypersensitivity reactions?[3+13]

8. Describe different types of systemic autoimmune diseases and explain in detail

about anyone of them? [4+12]

⋆⋆⋆⋆⋆

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Code No: RR322305 Set No. 4
III B.Tech II Semester Supplimentary Examinations, Aug/Sep 2008
IMMUNOLOGY
(Bio-Technology)
Time: 3 hours Max Marks: 80
Answer any FIVE Questions
All Questions carry equal marks
⋆⋆⋆⋆⋆

1. What are the various cells involved in the immune response and explain about their
role in immune response. [3+13]

2. Write a short notes on : [8+8]

(a) IgG.
(b) IgA.
(c) VH regions.
(d) Antibody valence.

3. Write a short notes on: [8+8]

(a) congenic.
(b) MHC class I
(c) MHC class II
(d) MHC class III

4. What are interferons and explain about various types of cytokines . [8+8]

5. Define hybridoma and explain monoclonal antibody production? [3+13]

6. Define agglutination and its mechanism in antigen - antibody interactions?[11+5]

7. Describe the various types of type III hypersensitivity? [16]

8. Give an account on the significance of autoimmunity in Immunology? [16]

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