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  • Vecuronium

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    Amanda La Sala
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    Vecuronium is a nondepolarizing neuromuscular blocking drug (NMBD) used for intubation in pediatrics and mechanical ventilation in adults. It works by competitively blocking acetylcholine receptors at the neuromuscular junction, preventing muscle contraction. Common side effects include skeletal muscle weakness and respiratory insufficiency. Nursing implications involve preadministration assessment, holding the medication under certain circumstances, and postadministration monitoring of respiratory function and muscle strength.

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    Vecuronium is a nondepolarizing neuromuscular blocking drug (NMBD) used for intubation in pediatrics and mechanical ventilation in adults. It works by competitively blocking acetylcholine receptors at the neuromuscular junction, preventing muscle contraction. Common side effects include skeletal muscle weakness and respiratory insufficiency. Nursing implications involve preadministration assessment, holding the medication under certain circumstances, and postadministration monitoring of respiratory function and muscle strength.

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    Download as DOCX, PDF, TXT or read online from Scribd
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    Download as docx, pdf, or txt
    423 views2 pages

    Vecuronium

    Uploaded by

    Amanda La Sala
    Vecuronium is a nondepolarizing neuromuscular blocking drug (NMBD) used for intubation in pediatrics and mechanical ventilation in adults. It works by competitively blocking acetylcholine receptors at the neuromuscular junction, preventing muscle contraction. Common side effects include skeletal muscle weakness and respiratory insufficiency. Nursing implications involve preadministration assessment, holding the medication under certain circumstances, and postadministration monitoring of respiratory function and muscle strength.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as DOCX, PDF, TXT or read online from Scribd
    Flag for inappropriate content
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    MEDICATION INFORMATION

    GENERIC NAME TRADE NAMES CLASSIFICATION

    Vecuronium

    Norcuron
    PEAK

    Nondepolarizing NMBD (intermediate acting)


    ONSET DURATION

    NORMAL DOSAGE RANGE (ALSO INCLUDE ROUTE AND FREQUENCY)

    3-5 min

    2.5-3 min

    25-40 min

    Pediatric -IV: 0.08-0.1 mg/kg Adult- IV: 0.08-0.1 mg/kg Continuous infusion: 0.1 mg/kg/hr
    LAB VALUE ALTERATIONS None listed DRUG INTERACTIONS

    Aminoglycosides, Calcium channel blockers, clindamycin, cyclophosphamide, cyclosporine ,dantrolene ,furosemide, Inhalation anesthetics ,Local anesthetics,magnesium ,polymyxin, procainamide ,quinidine
    Why is your patient getting this medication? Or What are some reasons that these medications are ordered? Pediatric- Intubation

    MECHANISM OF ACTION (How does it work?)

    Nondepolarizing NMBDs also bind to ACh receptors at the neuromuscular junction, but instead of mimicking ACh, they block its usual actions. Therefore, these drugs are competitive antagonists of ACh. Consequently, the nerve cell membrane is not depolarized, the muscle fibers are not stimulated, and skeletal muscle contraction does not occur.
    COMMON SIDE EFFECTS

    Adult- Mechanical ventilation

    Musculoskeletal: skeletal muscle weakness. Respiratory: prolonged, dose-related respiratory insufficiency or apnea.

    NURSING IMPLICATIONS (What to focus on.)

    TEACHING

    PREADMINISTRATION ASSESSMENT?

    WHEN/WHY WOULD YOU HOLD?

    WHAT WOULD YOU ASSESS POSTADMINISTRATION?

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