PICTOTRANS

Pathology of the Breast Quiz

From Dra. Edna May Lasap-Go
 Quiz choices
 Fibroadenoma
 Fibrocystic change
 Phylloides Tumor
 Comedocarcinoma/ DCIS
 Mucinous Carcinoma
 Invasive Ductal Carcinoma
 Lobular Carcinoma
 Tubular Carcinoma
 Papilloma
 Medullary Carcinoma
 Inflammatory Carcinoma
1.
 Clues from Ma’am
 well defined mass
 doughy to firm
 slit like spaces are seen with lobular
appearance
 Most seen in young patients fibroadenoma,
stromal, benign
 1. ANSWERS
 Diagnosis? FIBROADENOMA
 Of STROMAL origin
 Benign or Malignant? BENIGN
2.
2.
 Clues from Ma’am
 Frond-like/ fern-like structures within a cyst
 ANSWERS
 Diagnosis: PAPILLOMA CARCINOMA
 Most common clinical presentation
(aside from a palpable mass)?
BLOODY/SEROUS DISCHARGE
3.
 Clues from Ma’am
 Tumor with cellular stroma
 Arborizing patterns
 ANSWERS
 Diagnosis? PHYLLOIDES or
CYSTOSARCOMA PHYLLOIDES
(LOW GRADE)
 Stromal or Epithelial tumor?
STROMAL!
 Benign or Malignant? Can be
EITHER
4.
 Clues from Ma’am
 Tumor cells confined and
delimited; seen only inside
 At the center is necrotic debris
 ANSWERS
 Diagnosis? COMEDOCARCINOMA or
DCIS- ductal carcinoma in situ
 T/F: The lesion per se is an
invasive lesion. FALSE! Because it
is in situ.
 Note: Comedocarcinoma is a
subtype of ductal carcinoma (kaya
nga DCIS).
5.
5.
 Clues from Ma’am
 Gross: Glistening appearance
characteristic of the lesion because
of its gelatinous character
 ANSWERS
 Diagnosis? Mucinous Carcinoma
 T/F: This lesion has an excellent
prognosis. TRUE!
6.
 Clues from Ma’am
 Monomorphic cells arranged in
parallel arrays
 ANSWERS
 Diagnosis: LOBULAR CARCINOMA
 T/F: This lesion arises from the
lobules of the breast. FALSE! (Oo,
false).
7.
 Clues from Ma’am
 No myoepithelial cells so tumor
cells are in direct contact with
stroma.
 ANSWERS
 Diagnosis? TUBULAR CARCINOMA
 T/F: This histologic subtype has a
poor prognosis. FALSE! Because it
has EXCELLENT prognosis.
8.
8.
 Clues from Ma’am
 Gross: The white part is the lesion,
the red and yellow part is the
breast tissue.
 ANSWERS
 Diagnosis? INVASIVE DUCTAL
CARCINOMA
 Degree of differentiation: POORLY
DIFFERENTIATED
9.
 Clues from Ma’am
 Pushing borders
 Cells look like syncitium; you can’t
appreciate cell borders.
 ANSWERS
 Diagnosis: MEDULLARY
CARCINOMA