RSU Rx20

MCQ 1/2554
.... 5
clobetasol cream
1.
- Psoriasis
- Contact dermatitis
- Chicken pork
- Seborrheic dermatitis
2.
- Autoimmune
2
3.
- Actinomycin D
- Tacholimus
- Sulfasalazine
- Steroids
4. (choice )
-
-
-
-
- Autoimmune
-
5. steroids (choice )
-
-
-
-
-
-
6. steroids ( Cortisol)
7.

isotretinoin
1.
-

RSU Rx20

2.
- Doxycycline + Isotretinoin
- Tetracycline + Betamethazone cream

isotretinoin
3.
-
-
4. Isotretinoin
- Teratogenic
- Cytotoxic
5. Isotretinoin
- Case-control
- Cohort
- RCT

4 5 54
(6 54) 28
1.
-
- 20.00
- 8.00
- 20
- 20.00

2.
- 72
3. 8.00 . 15 54
- 20.00 . 15 54 ( 12 )
- 8.00 . 16 54
- 20.00 . 16 54
4.
- Levonorgestrel
- norethisterone
- lynestrenol

RSU Rx20

- norgestrel
- desogestrel
5. blister 28 2
- tamper containers
- tight containers
- light containers
- single unit containers ( )
- multiple dose containers
6.
-
- .............
-

1.
- Allergic conjunctivitis
- Bacterial conjunctivitis
- Viral conjunctivitis
- Blephritis
2. ( 2 )
- Tetrahydrozoline ()
- Dexamethasone eye drop
- chlorpheniramine tablets
- chloramphenicol eye drop
- chlortetracycline ointment
3. ophthalmic decongestant
- Antazoline (Antihistamine)
- phenylephrine ( )
- naphazoline
- oxymetazoline
- Tetrahydrozoline
4. Ophthalmic decongestant
- Angle Closure Glaucoma

RSU Rx20

5. ()
- Isotonic
- Sterile ( Hypertonic Sterile )
- pH
- Preservative
-
6.
- 1-2
-
-
-
-
7. NaCl 1 E 100 ml
- 25
8. cotrimoxazole
- Kernicterus
- Gray baby syndrome
- Reye syndrome
- Fanconi syndrome
9. Dexamethazone 2

-
10.
- Staphylococcus aureus

42 40 160
Cyclophosphamide

100 mg/mm2/day

MTX
5-FU

d 1-14
d 1-8

600 mg/mm2/day

d 1-8

Cycle 28 6 Cycle
1. 5-FU
5-FU 600 mg/m2/day

BSA (160x40)/3600 =1.33 m2

600 x 1.33 = 798 mg/day

RSU Rx20

- 600
- 700
- 800
- 900
- 1000
2. methotrexate
- Ulcerative stomatitis
3. 5-fluorouracil
- Leucovorin folinic acid
- Allopurinol
- Folic acid
- Mesna
- Cimetidine
4. MTX
- Dihydrofolate reductase inhibitors
5. alkylating cyclophosphamide
- Cisplatin
- Vincristine
- Doxorubicin
- Etoposide
6. 5-Fluorouracil Stomatitis
- Sucralfate
- Mesna
- Prednisolone
7. 1g 50 mg/ml ml ( DV. = 0.05 ml/100mg)
- 20.5
- 20.0
- 19.5
- 19.0
- 18.5

50 mg
1 ml

1000 mg
(1000 x 1) / 5 = 20 ml
100
mg
0.05 ml

1000 mg
(1000 x 0.05)/100 = 0.5 ml
DV 0.5 ml 20 0.5 = 19.5 ml

RSU Rx20

8. Cyclophosphamide 1 25 mg 50 mg / ( BSA = 1 m2)

ml. 1 cycle
Cyclophosphamide 100 mg/m2/day 1 -14
14 day x 100 mg/day = 1400 mg
1400/25 = 56
ml. (1 15 ml) = (56/2) x 15 = 420 ml.

80 60 kg Serum creatinine 2 mg/dL

CK 9 acute renal
failure 2 simvastatin ketoconazole
lab (
) FBS, BP K+
1. acute renal failure
- myoglobin induced
2.
- simvastatin
3. simvastatin => prodrug ( hydrolysis lactone ring
choice lactone ring )
4. creatinine clearance
Clcr = (140-80) x 60 / 2x72 = 25 ml/min
5. hyperkalemia
- Insulin + glucose
- Aluminium Hydroxide gel
6. AST/ALT
- Simvastatin
7. steroids
- Hypernatremia
- Hypercalcemia

acarbose, atenolol, aspirin.

1.
- Flatulence
- Hypoglycemia

RSU Rx20

2. hypoglycemia
- Atenolol
3.
- ACEIs
- Alpha-blockers
- Betablockers
- Loop diuretics
- Thiazide diuretics
4.
- Metformin
5. metformin
- Lactic acidosis
- Episode hypoglycemia
6. Maculopapular rash
-
7. Maculopapular rash ADR types
-A
- B ()
-C
-D
-E
8. skin pacth test type ( type I type IV delayed )
- Type I
- Type II
- Type III
- Type IV
9.
.........
- Cohort study
- Case Control study
- Cross sectional study
- Randomize control tried

RSU Rx20

Acyclovir
1.
- Herpes zoster
2.
- Varicella virus
- Rubella virus
3.
- Amitriptyline
- Ibuprofen
- Diazepam
4. S/E of Acyclovir
-
-
-
-
-
5. ( choice )
-
-
-
-
-
-
6.
- Acyclovir cream

1.
- Ibuprofen
2. cafergot
- 1-2 1 6
10

RSU Rx20

3.
-
4. Ergotamine ()
- Oxytocic
- Teratogenic
- Carcinogenic
4.
- Propranolol
- Cinnarizine
5. ergotamine
- Raynaud's phenomenon
6. Caffeine
- ergotamine
7. S/E Ergotamine
-

1.
- Lorazepam onset
2. Benzodiazepine substituted
- NO2 ring A
3. BZD
- Anterograde amnesia
4. BZD
- GABA receptor Cl channel hyperpolarization
5. Omeprazole MUP
- Diazepam (CYP2C19)
- Escitalopram
- Ketoconazole
6. Omeprazole MUP

- Ethylcellulose
- Cellulose acetate phthalate

RSU Rx20

10

- Hydroxypropylmethylcellulose
7.
-
-
- (
)
-
8. ( 5 )
- TCAs
- BZDs
- Typical Antipsychotics
9. omeprazole drug interaction
- clopidrogrel clopidrogrel
7.
- Benzodiazepines
weeks
8.
- Diazepam
9.
- Barakol
10. BZDs alcohol
- respiratory depression
11. BZDs
- Anxiety
- Alcohol withdrawal
12. Diazepam 2 mg
- 4

1.
-
-

RSU Rx20

11

-
-
-
2.
- Alcohol
- Povidone iodine
- NSS
- Clobetasol cream
3.
- Amoxicillin
- Dicloxacillin
4.
- Mupirocin ointment ( ointment
)
Choice cream
5.
- Alovela Gel
6.
- Staphylococcus aureus
7.
- Carbopol
8. Ethanol 70% 30 ml
- ( Ethanol Isopropyl)
9. OTOP
-
-

............. Hb = 9 (12-15), Hct = 27% MCV = 7 TIBC

hypochromic microcytis
1.
- Iron deficiency anemia
2.

RSU Rx20

12

- Ferrous sulfate ()
- Folic acid
- Blood transfusion ( blood transfusion Hct < 30%
[ ferrous 555 ])
3. Ferrous form
- Ferrous fumarate

MW = ...... 170

- Ferrous sulfate

MW = 170 choice MW

- Ferrous gluconate

MW = 300 (MW )

Ferrous sulfate mEq = ion / MW ion

mEq 1/ MW choice ferrous sulfate MW mEq
() ferrous fumarate
4.
- Ascobic acid 100 mg
5. Ferrous sulfate 100
-
6.
- Nausea/Vomitting
- Diarrhea
- Constipation
- Urine discoloration
- Dark stool
6.
- Thalassemia
7. Rx

Ferrous .
Ascorbic acid .
Water ml

-
-

onychomycosis
1.

RSU Rx20

13

- Trichophyton rubrum
- Malassezia furfur
2.
- Ciclopirox solution ()
- Clotrimazole cream
- Lacquer ( onychomycosis)
3.
- 1
- 3
- 6
-
4. Itraconazole pulse therapy
-
-
-
-
-
5. itraconazole CYP P450
- CYP3A4 inhibitors
6. itraconazole
- Fluconazole
- Griseofulvin ( dermatophyte )
- Terbinafene ( fungicidal sensitive )
7. amphotericin B
- ergosterol

1 .. 2
acute MI
1.
- ECG
2. enzyme
- Troponin + CK-MB

RSU Rx20

14

3.
- Aspirin 325 mg
4. Aspirin
- Enteric coated tablets
5. enteric coated
- Controlled release
- Sustained release
- Immediated release
- Delayed release
6.
- Sublingual
7. sublingual
- first pass metabolism
8. cGMP
- Nitrates
9. Metoprolol Metoprolol ()
10. Metropolol
-
-
Levodopa/benserazide On off phenomena (
2 )
1. levodapa
-
-
-
2. Levodopa
- Pergolide
- Bromocriptine
- Trihexyphenedyl
- Entacarpone
- Pramipexole

RSU Rx20
3. enzyme Dopamine
- MAOI
- COMT
4. levodopa
- HPLC
- Polarimeter
5. Levodopa Benserazide
- peripheral side effect
- Elimination
6. benseraside
- inhibit of decarboxylase enzyme
7. 6
- Decarboxylation
8. Extended Release
-
9. Levodopa
- Dyskinesia
10. Levodopa
- Decarboxylation
Thyroid
1.
-
2. toxic thyroid
- Graves disease
3. antithyroid drugs
- Methimazole
- Propylthiourea
4. hyperthyroids
- , ,
5.
- Lugols solution
6. Saturated solution of KI

15

RSU Rx20
-
- KI I2
- 12
- I2 KI
7. adjunctive treatment
- Propranolol
8.
-
9.
-

15 10 2
1.
- Vibrio cholera
- Shigella
- Rota virus
- Entamoeba histolytica
- Salmonella
2. ( ORS . ORS )
- Kaolin pectin
- Activated charcoal
- ORS
- Ultracarbon
- Dioctahedral smectite (SMECTA )
4. Cotrimoxazole 240 mg/kg b.i.d. x 3d
Sulfametroxazole/Trimetroprim 200/40 mg/5 ml
- 2
- 2
- 3
- 3
- 2
4. ORS
-

16

RSU Rx20

17

3.
Rx

NaCl

2.9 g

Na3citrate

2.9 g

Na mEq
4. XXX.anhydrous XXX XXX solution yyyy ml
5. cotrimaxole
- G6PD deficiency
6. ORS
-
-
- 24

Penicillin
1.
- Dextrometrophan
- Acetylcysteine
- Cetylpyridinium Chloride
- Paracetamol
- Tripolidine + Pseudoephedrine
2.
- Glyceryl guiacolate
- Acetylcysteine
- bromhexine
- ambroxol
3.
- Amoxicillin
- Cefazolin
- Erythromycin
- Clarithromycin
4.
- Clindamycin
- Cotrimoxazole

RSU Rx20
- Amoxicillin
5. Erythromycin

Lactone ring 14-16 carbons

6.
- Macrolides 30s ribosome
- Clindamycin 50s ribosome
7. 60 ml
-
8. Brown mixture
RA
1.
2.
3.
4.
- Glucosamine
- Methotrexate
- Sulfasalazine
- Celecoxib
5.
-
-

U/D: HTN, BPH 1 PTA 2PTA

UA: Prt. - RBC - WBC 100
1.
- Uncomplicated cystitis
- Complicated cystitis

18

RSU Rx20
- Uncomplicated pyelonephritis ( complicated )
- Complicated pyelonephritis ()
2.
- Norfloxacin 400 mg 3
- Norfloxacin 400 mg 5
- Ciprofloxacin 500 mg 14
3. Fluoroquinolone

- COOH
-F
4. Norfloxacin
- (check )
-
-
-
-
5.
-
-
- ....
6. lab
- Urine culture
- Complete blood count
- VRDL

Hypertension simvastation gemfibrozil Rhabdo

1. lab ( monitor CPK liver function tests)
- Serum creatinine
- CPK Liver function test
2. gemfibrozil TG 250
- Fish oil high dose ( TG )

19

RSU Rx20

20

- Cholestyramine
- Ezetimibe ( TG )
- Fenofibrate ()
5.
-
simvastatin
- Ezibtimite simvastatin
- CPK and liver function tests simvas 80 mg 3

case COPD
1. seretide
-
2. binder
3. salbutamol s-form r-form
- Enantiomer
- Diastomer
-
-
4. Salbutamol S/E
-

RSU Rx20

21

555
- omeprazole cisapride => QT prolongation
- ferrous sulfate 20%
- => Choice

- capping => binder
- omeprazole => H+/K+ ATPase (choice Na+/K+ ATPase digoxin ,,,,,,,)
- omeprazole => pellet
- =>
- => Colliodal silicon dioxide
- disintegant => Sodium starch glycolate
-
- steroid 1. Hydrocortisone 2.dexa 3.prednisolone 4..
- Side effect steroid => hypernatemia
- suspensions : Caking
- Antimony Glycyrrhiza fluidextract
- ointment
- Suspension flocculating agent suspending agent
- flocculating agent suspending agent
- 3 pH BHT

- Hydrolysis
- Oxidation
- Photolysis
- Hydrolysis Oxidation
- Oxidation Photolysis ()
- amorphous crystalline 2

-
- 3 route
. Z-test

. Paired T-test

. Independent T-test

. F-test

. Mann Withney U-test

RSU Rx20
- cytotec spastolytic , cytolytic
-
- Capsule 5
- Metoprolol () SE
- Enalapril ()

22