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Pathophysiology of chronic bronchitis

Inhaled air with smoke Nicotine to alveoli Hardened elastic fiber Decrease recoil Inflammation reaction in the airway Release of IgE Release of histamine Bronchial swelling Goblet hyprthrophy Defective ventilation Impaired ventilation-perfusion process

Decrease elastic recoil Decrease volume capacity Decrease pulmonary blood fibers Decrease tissue perfusion Clubbing fingers

mucosecretion air trapping prolong exchange of O2 and CO dyspnea dyspnea and hypercapnia

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