Vic sn xut qui m ln viCorynebacterium glutamicum bt u vo u nm 1958 thc vt ca Kyowa Hakko Nht Bn Nhng cng ty khc tham gia

gia vic thng mi v sau sut 4 thp k sn xut vi

Corynebacterium glutamicum

Cng ngh sinh hc ch to ra L-Lysine c ci thin khng ngng v s tin b v k thut to ra s lng ln lysine p ng nhu cu ngy nay

Gii thiu
.Gii thiu chung v acid amin
Cc acid amin c cu trc c trng nh sau: Cc acid amin c cu trc c trng nh sau: NH NH2
2

R-CH R-CH3 3- COOH - COOH H H

Acid amin tn ti 2 dng ng phn quang hc : Acid amin tn ti 2 dng ng phn quang hc :

dng D v dng L dng D v dng L a s acid amin tn ti dng rn v l dng tinh th trong iu kin bnh thng. Chng b ph hy nhit cao ( 200 300oC ), a s cc acid amin u cho mu tm xanh khi tng tc vi ninhydrin.

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PHN I :TNG QUAN V LYSINE

I.1.Gii thiu chung v acid amin I.1.Gii thiu chung v acid amin - L thnh phn cu to nn protein, enzym, cc vitamin, cht kch thch sinh trng, hocmon v khng sinh, khng th. - C 8 acid amin thuc nhm acid amin khng thay th, l : isoleusine, leucine, lysine, methionine, phenylalanine, threonine, tryptophan v valine. Trong , lysine l mt aicd amin rt quan trng

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PHN I :TNG QUAN V LYSINE

H acid amin thm H acid amin thm : phenylalanin , : phenylalanin , triptophan , tirozin triptophan , tirozin H aspactat H aspactat : asparagin , acid aspactic , : asparagin , acid aspactic , izoloxin , lisine , metionin izoloxin , lisine , metionin treonin treonin H glutamat H glutamat : alanin , loxin , valin : alanin , loxin , valin H xerin H xerin : xixtein , glixin , xerin : xixtein , glixin , xerin

Acid amin c phn thnh mt s h trn c s cc phn ng m u chung trong qu trnh sinh tng hp.

I.1.Gii thiu chung v acid amin

I.1 . Khi nim Lysine

Tn quc t : 2,6-diaminohexanoic acid Cng thc ha hc: C6H14 N2O2 Khi lng phn t gam: 146.188 g/mol Lysine l mt -amino acid
Lysine l mt axit amin thuc h aspartat c tng hp qua con ng trao i cht (phn nhnh).

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PHN I :TNG QUAN V LYSINE

I.3. c