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  • Liver Physiology 52

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    Surintorn Duangchaingoen
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    The document summarizes the key findings of a study on metallomics and proteomics analysis of foreign body response to implanted biomaterials. The main findings are: 1. The study identified elevated levels of zinc, copper, and iron ions in tissues surrounding implanted materials, indicating a metallomic response. 2. Proteomic analysis revealed increased levels of reactive oxygen species-degrading and wound healing proteins near implants, showing an inflammatory response. 3. The release of metal ions from degrading implants influences the cellular response and may contribute to implant failure through toxicity or interference with wound healing.

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    The document summarizes the key findings of a study on metallomics and proteomics analysis of foreign body response to implanted biomaterials. The main findings are: 1. The study identified elevated levels of zinc, copper, and iron ions in tissues surrounding implanted materials, indicating a metallomic response. 2. Proteomic analysis revealed increased levels of reactive oxygen species-degrading and wound healing proteins near implants, showing an inflammatory response. 3. The release of metal ions from degrading implants influences the cellular response and may contribute to implant failure through toxicity or interference with wound healing.

    Copyright:

    Attribution Non-Commercial (BY-NC)
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    7 views71 pages

    Liver Physiology 52

    Uploaded by

    Surintorn Duangchaingoen
    The document summarizes the key findings of a study on metallomics and proteomics analysis of foreign body response to implanted biomaterials. The main findings are: 1. The study identified elevated levels of zinc, copper, and iron ions in tissues surrounding implanted materials, indicating a metallomic response. 2. Proteomic analysis revealed increased levels of reactive oxygen species-degrading and wound healing proteins near implants, showing an inflammatory response. 3. The release of metal ions from degrading implants influences the cellular response and may contribute to implant failure through toxicity or interference with wound healing.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as PPT, PDF, TXT or read online from Scribd
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