aLhophyslology of LepLosplrosls

Predisposing Factor:
Dirty environment, age,
seasons, males, geographic
areas
aLLle swlre and
oLher llvesLock
History taking (history of
exposure)
8odenLs wlld anlmals
uogs
LnLry Lhrough eyes nose and
broken skln
lnfecLed urlne or carcasses
Man
lngesLlon of conLamlnaLed food
and waLer
lncubaLes for 6 Lo
13 days
roflleraLlon and wldespread dlssemlnaLlon
AsympLomaLlc
Crgan sysLems are affecLed
kldney and Llver
luncLlons 1esL
Immune or 1ox|c stage
an be wlLh or wlLhouL [aundlce lasL for 4 Lo 30
days lrlLls headache menlngeal manlfesLaLlons


















ept|c stage
lebrlle lasLlng for 4 Lo 7days
chllls head ache anorexla
abdomlnal paln
Conva|escence
8elapse may occur
durlng 4
Lh
o 3
Lh
week
Leptosp|ros|s
8lood ulLure
l and urlne
culLure
AggluLlnaLlon LesL
Comp||cat|ons
neumonla
CpLlc neurlLls
erlpheral neurlLls
Death