Drug Name

Dosage and
koute

Act|on

Ind|cat|on]Contra|nd|cat|on

Adverse Lffects

Nurs|ng kespons|b|||t|es

Gener|c Name
lurosemlde

8rand Name
lumlde
luromlde
Laslx Luramlde

C|ass|f|cat|ons
LlecLrolyLlc and
waLer balance
agenL Loop
ulureLlc




Ldema
Adu|t9 2080
mg ln 1 or more
dlvlded doses up
Lo 600mg/d lf
needed IV]IM 20
40 mg ln 1 or
more dlvlded
doses up Lo
600mg/dl
d C
2mg/kg may be
lncreased by 1
2mg/kg q68h
IV]IM 1 mg/kg
may be lncreased
by 1 mg/kg q2h lf
needed
Neonote C 14
mg/kg q1224h
IV]IM 12mg/kg q
1224h

nypertens|on
t C 10
40mg 8lu (max
480 mg/dl)

1 tob once
o oy

8apldacLlng
poLenL
sulfonamlde
loop" dlureLlc
and
anLlhyperLenslve
wlLh
pharmacologlc
effecLs and uses
almosL ldenLlcal
Lo Lhose of
eLhacrynlc acld
LxacL mode of
acLlon noL
clearly deflned
decreases renal
vascular
reslsLance and
may lncrease
renal blood flow

Ind|cat|on
@reaLmenL of edema
assoclaLed wlLh CPl
clrrhosls of llver and kldney
dlsease lncludlng nephroLlc
syndrome


Contra|nd|cat|on
PlsLory of hypersenslLlvlLy
Lo furosemlde or
sulfonamldes lncreaslng
ollgurla anurla fluld and
elecLrolyLe depleLlon sLaLes
heapaLlc coma pregnancy
caLegory C lacLaLlon

9osLural
hypoLenslon
dlzzlness wlLh
excesslve dleresls
acuLe hypoLenslve
eplsodes
clrculaLory collapse
hypovolemla
dehydraLlon
hyponaLremla
hypokalemla
nausea and
vomlLlng
consLlapaLlon

O ConsulL physlclan
regardlng allowable salL
and fluld lnLake
O lngesL poLasslumrlch
foods dally (eg
bananas oranges
peaches drled daLes) Lo
reduce or prevenL
poLasslum depleLlon
O Learn SS of
hypokalemla (see
Appendlx l) 8eporL
muscle cramps or
weakness Lo physlclan
O ,ake poslLlon changes
slowly because hlgh
doses of
anLlhyperLenslve drugs
Laken concurrenLly may
produce eplsodes of
dlzzlness or lmbalance
O Avold replaclng fluld
losses wlLh large
amounLs of waLer
O Avold prolonged
exposure Lo dlrecL sun
O uo noL breasL feed whlle
Laklng Lhls drug




Drug Name


Dosage and
koute

Act|on

Ind|cat|on]
Contra|nd|cat|on

S|de Lffects

Nurs|ng kespons|b|||t|es

Gener|c Name
nldedlplne

8rand Name


C|ass|f|cat|ons
Calclum channel
blocker
anLlanglnal
anLlhyperLenslve

20mg C 1ID

lnhlblLs Lhe movemenL of
calclum lons across Lhe
membranes of cardlac and
arLerlal muscle cells
lnhlblLlon of
Lransmembrane calclum
flow resulLs ln Lhe
depresslon of
lmpulse formaLlon ln
speclallzed cardlac
pacemaker cells ln slowlng
of Lhe veloclLy of conducLlon
of Lhe cardlac lmpulse ln
Lhe depresslon of
myocardlal conLracLlllLy and
ln
Lhe dllaLlon of coronary
arLerles and arLerloles and
perlpheral arLerloles Lhese
effecLs lead
Lo decreased cardlac work

Ind|cat|on
PyperLenslon chronlc
sLable anglna anglna
pecLorls due Lo coronary
arLery spasm

Contra|nd|cat|on
PypersenslLlvlLy Lo
nlfedlplne pregnanL and
lacLaLlng moLhers

ulzzlness llghL
headedness
headache asLhenla
faLlgue nervousness
sleep dlsLurbances
blurred vlslon
nausea dlarrhea
consLlpaLlon cramps
flaLulence hepaLlc
ln[ury



ASSLSSMLN1
n|story Allergy Lo
nlfedlplne pregnancy
lacLaLlon
hys|ca| Skln leslons
color edema orlenLaLlon
reflexes 9 89 basellne
LCC perlpheral
perfuslon ausculLaLlon 8
advenLlLlous sounds llver
evaluaLlon normal Cl
ouLpuL llver funcLlon LesLs

IN1LkVLN1ICNS
,onlLor paLlenL carefully
(89 cardlac rhyLhm and
ouLpuL) whlle drug ls belng
ad[usLed Lo LherapeuLlc
dose Lhe dosage may be
lncreased more rapldly ln
hosplLallzed paLlenLs under
close supervlslon uo noL
exceed 30 mg/dose
lncreases
8eporL lrregular hearLbeaL
ShorLness of breaLh swelllng of
hands and feeL pronounced
dlzzlness consLlpaLlon


Drug Name


Dosage and
koute

Act|on

Ind|cat|on]Contra|nd|cat|on

Adverse Lffects

Nurs|ng kespons|b|||t|es

Gener|c Name


8rand Name
lumlde
luromlde
Laslx Luramlde

C|ass|f|cat|ons
LlecLrolyLlc and
waLer balance
agenL Loop
ulureLlc




Ldema
Adu|t9 2080
mg ln 1 or more
dlvlded doses up
Lo 600mg/d lf
needed IV]IM 20
40 mg ln 1 or
more dlvlded
doses up Lo
600mg/dl
d C
2mg/kg may be
lncreased by 1
2mg/kg q68h
IV]IM 1 mg/kg
may be lncreased
by 1 mg/kg q2h lf
needed
Neonote C 14
mg/kg q1224h
IV]IM 12mg/kg q
1224h

nypertens|on
t C 10
40mg 8lu (max
480 mg/dl)

1 tob once
o oy

8apldacLlng
poLenL
sulfonamlde
loop" dlureLlc
and
anLlhyperLenslve
wlLh
pharmacologlc
effecLs and uses
almosL ldenLlcal
Lo Lhose of
eLhacrynlc acld
LxacL mode of
acLlon noL
clearly deflned
decreases renal
vascular
reslsLance and
may lncrease
renal blood flow

Ind|cat|on
@reaLmenL of edema
assoclaLed wlLh CPl
clrrhosls of llver and kldney
dlsease lncludlng nephroLlc
syndrome


Contra|nd|cat|on
PlsLory of hypersenslLlvlLy
Lo furosemlde or
sulfonamldes lncreaslng
ollgurla anurla fluld and
elecLrolyLe depleLlon sLaLes
heapaLlc coma pregnancy
caLegory C lacLaLlon

9osLural
hypoLenslon
dlzzlness wlLh
excesslve dleresls
acuLe hypoLenslve
eplsodes
clrculaLory collapse
hypovolemla
dehydraLlon
hyponaLremla
hypokalemla
nausea and
vomlLlng
consLlapaLlon

O ConsulL physlclan
regardlng allowable salL
and fluld lnLake
O lngesL poLasslumrlch
foods dally (eg
bananas oranges
peaches drled daLes) Lo
reduce or prevenL
poLasslum depleLlon
O Learn SS of
hypokalemla (see
Appendlx l) 8eporL
muscle cramps or
weakness Lo physlclan
O ,ake poslLlon changes
slowly because hlgh
doses of
anLlhyperLenslve drugs
Laken concurrenLly may
produce eplsodes of
dlzzlness or lmbalance
O Avold replaclng fluld
losses wlLh large
amounLs of waLer
O Avold prolonged
exposure Lo dlrecL sun
O uo noL breasL feed whlle
Laklng Lhls drug