Drug Analysis

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DkUG ANALSIS

Drug Name Mechan|sm of


Act|on
Dosage Ind|cat|on Contra|nd|cat|on S|de effects]
Adverse effects
Nurs|ng kespons|b|||t|es
Cenerlc name
MeLformln

8rand name
lMAx

Class
AnLldlabeLlc
MeLformln
prlmarlly
reduces/decreas
ed hepaLlc
glucose
formaLlon and
lncreases
perlpheral
glucose upLake

300 mg/Lab 1lu

AdulLs 300 8lu or
830 once dally C

edlaLrlc paLlenLs
(1016 y/o)
300 mg 8lu wlLh
meals


used ln Lhe
LreaLmenL of
nonlnsulln
dependenL
uM

lL can be used
as a
monoLherapy
or ln
comblnaLlon
wlLh a
sulfonylurea
ConLralndlcaLed
wlLh allergy Lo
meLformln hearL
fallure dlabeLes
compllcaLed wlLh
fever severe
lnfecLlons severe
Lrauma ma[or
surgery keLosls
acldosls coma
Lype 1 dm serlous
hepaLlc
lmpalrmenL
serlous renal
lmpalrmenL
glycosurla
hyperglycemla
assoclaLed wlLh
prlmary renal
dlsease labor and
dellvery lacLaLlon

use cauLlously wlLh
Lhe elderly
Lndocrlne
Pypoglycemla LacLlc
acldosls

Cl Anorexla nausea
vomlLlng eplgasLrlc
dlscomforL hearLburn
dlarrhea flaLulence

PypersenslLlvlLy
Allerglc skln reacLlons
eczema prurlLus
eryLhema urLlcarla

MonlLor urlne or serum


glucose levels frequenLly
Lo deLermlne
effecLlveness of drug and
dosage

MonlLor blood for glucose
and keLones as
prescrlbed

Swallow exLendedrelease
LableLs whole do noL cuL
crush or chew

Avold alcohol whlle Laklng
Lhe drug

8eporL fever sore LhroaL
unusual bleedlng or
brulslng rash dark urlne
llghL colored sLools
hypoglycaemlc or
hyerglycemlc reacLlons




Drug Name Mechan|sm of
Act|on
Dosage Ind|cat|on Contra|nd|cat|on S|de effects]
Adverse effects
Nurs|ng kespons|b|||t|es
Cenerlc name
Cllclazlde

8rand name
ulamlcron

Class
AnLldlabeLlc
sulfonylurea
ulamlcron
conLalns Lhe
acLlve lngredlenL
gllclazlde whlch ls
a sulfonylurea
Cllclazlde ls used
Lo help conLrol
blood sugar
levels wlLh uM ll

30 mg/Lab Cu


used ln Lhe
LreaLmenL of
uM ll when
dleL exerclse
and welghL loss
have falled Lo
fully conLrol
blood sugar
ConLralndlcaLed
wlLh
hypersenslLlclLy Lo
sulfonylurea 1o
Lhose havlng uM l
severe hepaLlc or
renal fallure
pregnancy and
lacLaLlon dlabeLlc
keLoacldosls
Cl ularrhea
consLlpaLlon
lndlgesLlon nausea
vomlLlng or abdomlnal
paln

Skln reacLlons rashes
and lLch

ulsLurbance ln llver
funcLlon

Low blood glucose
level

?ellowlng of Lhe skln
([aundlce)

O
aLlenLs who are nC may
have Lhelr dose held Lo
avold hypoglycemla

lnform Lhe docLor ln Lhe
ff cases Surgery Lrauma
fever or lnfecLlon
dlfflculLy ln eaLlng

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