Professional Documents
Culture Documents
Hyperemesis Gravidarum
Hyperemesis Gravidarum
Benediktus Andries (2009-061-152) Devi Rita Rohani (2009-061-337) Martin Reingie (2010-061-013)
Definition
EPIDEMIOLOGY The peak incidence is at 8-12 weeks of pregnancy, and symptoms usually resolve by week 20 in all but 10% of patients. Hyperemesis is the second leading cause of hospitalization in pregnancy, second only to preterm labor. Patients younger than 30 years are more likely to experience hyperemesis.
Pathophysiology
Risk Factor
Young maternal age
Mola pregnancy
CLINICAL PRESENTATION
Findings at physical examination (usually at the 1st trimester) may include the following : 1. Nausea & vomiting 2. Weight loss 3. Dehydration decreased skin turgor 4. Postural changes in blood pressure (BP) and pulse Laboratory : Hemoglobin and Hematocrit, hyponatremia, hypokalemia, proteinuria, ketonuria
Clinical manifestation
Overall condition - ability to perform daily activities; psychological state of mind Weight measurement - to determine if you have lost weight Blood electrolytes - to identify disturbances in salts and other minerals in the blood due to extreme vomiting Ketones - to determine if you are dehydrated
COMPLICATIONS
Complications
of vomiting rarely occur. Women with hyperemesis and poor weight gain have lower average birth weights and are more likely to have a small for gestational age infant and may be at higher risk for preterm birth. Without thiamine supplementation, Wernicke encephalopathy may occur (ie, diplopia, nystagmus, disorientation, confusion, coma). If treatment is unsuccessful, complications of prolonged dehydration and starvation may occur.
Treatment
PROGNOSIS
Women
who gained less than 7 kg in pregnancy were more likely to have fetal complications, but those with hyperemesis and greater than 7 kg weight gain had no increased risk. This research indicates that treating hyperemesis gravidarum such that the patient is able to gain weight portends a better prognosis.
Thank You
Click to edit Master subtitle style