DRUG ANALYSIS

DRUG NAME 1. Ceferoxime 950mg MECHANISMS OF ACTION y Secondgeneration cephalosporin that inhibits cellwall synthesis, promoting osmotic instability; usually bactericidal INDICATIONS y Patients with urinary tract infection (UTI) CONTRAINDICATIONS y Contraindicated in patients hypersensitive to drug or other cephalosporins Use cautiously in patients hypersensitive to penicillin because of possibility of cross-sensitivity with other betalactam antibiotics. Contraindicated in patients hypersensitive to drug Use cautiously in patients with suspected cardiac disease, CVA and those taking hypesensitives y SIDE EFFECTS NURSE S RESPONSIBILITY Nausea, vomiting, y Before anorexia, administration, diarrhea, ask patient if he increase is allergic to temperature, penicillins or anaphylaxis. cephalosporins. y Monitor patient for signs and symptoms of superinfection.

2. Apresolin 5mg

Unknown. A y direct-acting vasodilator that relaxes arteriolar smooth muscle.

Severe essential hypertension (parenterally , to lower blood pressure quickly)

Headache, dizziness, tachycardia, edema, palpitations nausea, vomiting, constipation.

3. Dexamethasone 8mg

Not clearly defined. Decreases

Inflammatory conditions, allergic

Contraindicated to patients with hypersensitivity to

Headache, hypertension, edema,

Monitor patient s blood pressure, pulse rate, and body weight frequently. y Monitor patient closely for signs and symptoms of lupuslike syndrome (fever, sore throat, muscle and joint aches, rash) and notify doctor or nurse on duty if they develop y Determine whether patient is sensitive to

DRUG ANALYSIS
inflammation, mainly to stabilizing leukocyte lysosomal membranes; suppresses immune response; stimulates bone marrow; and influences protein, fat and carbohydrate metabolism. reactions, shock, cerebral edema the drug. Use cautiously in patients with hypertension thromboembolis m, nausea, vomiting, rebound inflammation, fatigue, weakness, fever, dizziness. other corticosteroids Monitor patient s blood pressure, weight and electrolyte levels For better results and less toxicity, give once-daily dose in morning Give oral dose with food if possible. Patient may need medication to prevent GI irritation