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    AMA Phatophysiology

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    namonne
    This document summarizes the pathophysiology of stroke. It identifies predisposing factors like age, heredity, sex, and prior health conditions. Precipitating factors include hypertension, smoking, atrial fibrillation, poor diet, and alcohol intake. These can lead to atherosclerosis and thrombosis, obstructing major blood vessels. Hypertension can also weaken and damage blood vessel walls. This can cause cerebral hemorrhage or cerebral ischemia. Impaired blood flow and oxygen distribution to the brain can then cause tissue hypoxia, cellular starvation, and ischemic damage. This pathophysiological cascade can ultimately lead to cerebral death and systemic failure in severe cases.

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    AMA Phatophysiology

    Uploaded by

    namonne
    24 views3 pages
    This document summarizes the pathophysiology of stroke. It identifies predisposing factors like age, heredity, sex, and prior health conditions. Precipitating factors include hypertension, smoking, atrial fibrillation, poor diet, and alcohol intake. These can lead to atherosclerosis and thrombosis, obstructing major blood vessels. Hypertension can also weaken and damage blood vessel walls. This can cause cerebral hemorrhage or cerebral ischemia. Impaired blood flow and oxygen distribution to the brain can then cause tissue hypoxia, cellular starvation, and ischemic damage. This pathophysiological cascade can ultimately lead to cerebral death and systemic failure in severe cases.

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    This document summarizes the pathophysiology of stroke. It identifies predisposing factors like age, heredity, sex, and prior health conditions. Precipitating factors include hypertension, smoking, atrial fibrillation, poor diet, and alcohol intake. These can lead to atherosclerosis and thrombosis, obstructing major blood vessels. Hypertension can also weaken and damage blood vessel walls. This can cause cerebral hemorrhage or cerebral ischemia. Impaired blood flow and oxygen distribution to the brain can then cause tissue hypoxia, cellular starvation, and ischemic damage. This pathophysiological cascade can ultimately lead to cerebral death and systemic failure in severe cases.

    Copyright:

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    Download as DOC, PDF, TXT or read online from Scribd
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    Download as doc, pdf, or txt
    24 views3 pages

    AMA Phatophysiology

    Uploaded by

    namonne
    This document summarizes the pathophysiology of stroke. It identifies predisposing factors like age, heredity, sex, and prior health conditions. Precipitating factors include hypertension, smoking, atrial fibrillation, poor diet, and alcohol intake. These can lead to atherosclerosis and thrombosis, obstructing major blood vessels. Hypertension can also weaken and damage blood vessel walls. This can cause cerebral hemorrhage or cerebral ischemia. Impaired blood flow and oxygen distribution to the brain can then cause tissue hypoxia, cellular starvation, and ischemic damage. This pathophysiological cascade can ultimately lead to cerebral death and systemic failure in severe cases.

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    of 3

    II.

    PHATOPHYSIOLOGY
    Predisposing Factors: 1) Age: 48 y/o 2) Heredity: Mother died because of stroke 3) Sex: Male 4) Prior Stroke, TIA or heart attack Precipitating Factors: 1) Hypertension 2) Cigarette Smoking 3) Atrial Fibrillation 4) Poor diet 5) Alcohol Intake

    Atherosclerosis Formation of Plaque deposits Thrombosis Occlusion by major vessel

    Hypertensi on

    Lysed or moved thrombus from the vessel

    Vascular wall becomes weakened and fragile

    Leaking of blood from the fragile vessel wall Sx:, headache, unconsciousness, nausea/vomiting, visual disturbances

    Cerebral Hemorrhage Mass of blood forms and grows

    Vasospasm of tissue and arteries

    Sx: dizziness, confusion, headache

    CEREBRAL HYPOPERFUSION

    Impaired distribution of oxygen and glucose

    Blood seeps into th e ventricles Obstruction of CSF passageway

    Formation of small and large clots

    Impaired distribution of oxygen and glucose

    Tissue hypoxia and cellular starvation

    Cerebral Ischemia Accumulation of CSF in the ventricles Lodges unto other cerebral arteries

    Initiation of ischemic cascade

    Ventricles dilate behind the point of obstruction

    Increased ICP Unrelieved obstruction

    Anaerobic metabolism by mitochondria

    Vertebrobasilar System

    Damage to the blood vessel endothelium

    Transient Ischemic Attack Structural integrity loss of brain tissue and blood vessels Brain sustains an irreversible cerebral damage

    Breakdown of the protective Blood Brain Barrier

    Cerebral edema

    Compression of tissue

    Vascular Congestion

    Increased intracranial pressure Impaired perfusion and function

    Sx: Alternating motor weaknesses, contralateral hemisensory impairments, double vision, homonymous hemianopsia, nystagmus, conjugate gaze, paralysis, dysphagia, coma

    Vertebrobasilar System Cerebellum and brain stem

    Continued insufficiency of blood flow

    Further compression of tissues

    Coma

    Cerebral Death

    Loss of neural feedback mechanisms

    Cessation of physiologic functions

    Altered body temperature


    Systemic Failure

    Impaired Gas exchange

    Risk for aspiration r/t NGT use

    In Severe Cases

    DEATH

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