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  • Herpes Simplex

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    Syazwan Aziz
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    Herpes simplex is an acute infection caused by the herpes simplex virus (HSV), which typically presents with vesicles on an erythematous base and can recur. It has a worldwide distribution, with HSV-1 usually causing oral infection in childhood and HSV-2 typically causing genital infection in the 2nd and 3rd decades of life and correlating with sexual behavior. Both viruses spread through direct contact with infected secretions, replicate at the site of infection, travel to dorsal root ganglia, and establish latency until reactivation.

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    Herpes simplex is an acute infection caused by the herpes simplex virus (HSV), which typically presents with vesicles on an erythematous base and can recur. It has a worldwide distribution, with HSV-1 usually causing oral infection in childhood and HSV-2 typically causing genital infection in the 2nd and 3rd decades of life and correlating with sexual behavior. Both viruses spread through direct contact with infected secretions, replicate at the site of infection, travel to dorsal root ganglia, and establish latency until reactivation.

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    12 views1 page

    Herpes Simplex

    Uploaded by

    Syazwan Aziz
    Herpes simplex is an acute infection caused by the herpes simplex virus (HSV), which typically presents with vesicles on an erythematous base and can recur. It has a worldwide distribution, with HSV-1 usually causing oral infection in childhood and HSV-2 typically causing genital infection in the 2nd and 3rd decades of life and correlating with sexual behavior. Both viruses spread through direct contact with infected secretions, replicate at the site of infection, travel to dorsal root ganglia, and establish latency until reactivation.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as DOCX, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    Download as docx, pdf, or txt
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    HERPES SIMPLEX

    DEFINITION: Acute infection caused by the herpes simplex virus (HSV) or herpesvirus hominis type 1 or 2 with typical symptoms group of vesicles on erythematous base and recurrent

    EPIDEMIOLOGY: y y y Worldwide distribution Primary infection HSV-1 childhood

    ETIOLOGY: y y y HSV-1 and HSV-2 human DNA viral pathogens HSV-1 orofacial disease HSV-2 genital infection

    HSV-2 2nd and 3rd decade age, correlates with sexual behavior

    PATHOGENESIS: y HSV-1 is spread primarily through direct contact with contaminated saliva or other infected secretions. HSV-2 is spread primarily by sexual contact. Virus will replicate at the site of infection (i.e. the mucocutaneous surface), travel by retrograde axonal flow to the dorsal root ganglia, and establish latency until reactivation.

    y y

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