Non-Modifiable Factors age: 67 Female Pacific Islander Genetics

Modifiable Factors weight Sedentary Life style Environmental conditions

Resistant insulin receptors Ineffective glucose transport Inadequate uptake of insulin into the cells, Pancreas is stimulated to produce more insulin Degeneration of pancreatic beta cells

Inadequate supply of nutrients to the tissues

neuropathy

[Decrease insulin production

Loss of peripheral sensation Hyperglycemia Painless trama Diabetes Mellitus ulceration Slow wound healing infection dehydration Polyuria Osmotic diuresis

Polydipsia

Moderate sized gangrene

Amputation of infected area