Scribd Logo
Upload

Welcome to Scribd!

  • Bioabsorbable Stenting PLA

    Uploaded by

    schaderaustin
    14 views2 pages
    1) The document assessed the validity of using PolyLactic Acid (PLA) polymer for bioabsorbable stents by testing its biocompatibility, degradation rate, and structural stability under various conditions. 2) PLA rings degraded rapidly, losing mass daily, making results inconclusive on the effects of pH, artery size, and flow on degradation rates. 3) PLA was found to degrade too quickly to maintain structural strength for 6 months as required, so further testing of biocompatible copolymers is recommended to reduce the degradation rate for use in stents.

    Original Description:

    Copyright

    © Attribution Non-Commercial (BY-NC)

    Available Formats

    PDF, TXT or read online from Scribd

    Did you find this document useful?

    Is this content inappropriate?

    Report this Document
    1) The document assessed the validity of using PolyLactic Acid (PLA) polymer for bioabsorbable stents by testing its biocompatibility, degradation rate, and structural stability under various conditions. 2) PLA rings degraded rapidly, losing mass daily, making results inconclusive on the effects of pH, artery size, and flow on degradation rates. 3) PLA was found to degrade too quickly to maintain structural strength for 6 months as required, so further testing of biocompatible copolymers is recommended to reduce the degradation rate for use in stents.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as PDF, TXT or read online from Scribd
    Flag for inappropriate content
    Download as pdf or txt
    14 views2 pages

    Bioabsorbable Stenting PLA

    Uploaded by

    schaderaustin
    1) The document assessed the validity of using PolyLactic Acid (PLA) polymer for bioabsorbable stents by testing its biocompatibility, degradation rate, and structural stability under various conditions. 2) PLA rings degraded rapidly, losing mass daily, making results inconclusive on the effects of pH, artery size, and flow on degradation rates. 3) PLA was found to degrade too quickly to maintain structural strength for 6 months as required, so further testing of biocompatible copolymers is recommended to reduce the degradation rate for use in stents.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as PDF, TXT or read online from Scribd
    Flag for inappropriate content
    Download as pdf or txt
    of 2

    _______________________________________________________________________________________________________________ _____________________________________________________________________________________________________________ Objective To assess the validity in PolyLactic Acid (PLA) derived polymer for use in bio absorbable

    stenting. Additionally to test various body types on degradation rates including PH, Artery Size, and Flow Rates User Needs 1) Full Biocompatibility 2) Fully Degrade within 12 months 3) Maintain adequate structural stability for 6 months 4) Be geometrically formable and deployable as a stent Testing Setup and PLA Rings Results
    PLA was formed into rings which were sampled daily, and measured for mass lost, to calculate the degradation rate.

    PolyLactic Acid Polymer Based Stents

    PLA degradation becomes evident after only one week in solution.

    PLA was determined to follow Le Chateliers Principle for degradation. Results were inconclusive to the effects of PH, Artery Size, and Flow on degradation rates. Samples were determined to lose structural strength too quickly for use in stenting. Further testing is recommended to determine biocompatible polymers for use in copolymerizing to reduce the biodegradation rate. Contact Info: aschader@calpoly.edu, Austin Schader

    You might also like