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O8 Jan 1
O8 Jan 1
M.B.B.S. PHASE - II Degree Examination - January 2008 PHARMACOLOGY - PAPER I (Revised Scheme)
QP Code: 1060
Your answers should be specific to the questions asked. Draw neat labeled diagrams wherever necessary. LONG ESSAY 1. 2. 2 X 9 = 18 Marks
Describe the drug treatment of Glaucoma giving pharmacological rationale for each drug Classify diuretics giving suitable examples from each class. Enumerate therapeutic uses of Thiazide diuretics. What are the complications of diuretic therapy? 10 X 5 = 50 Marks
SHORT ESSAY 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. Factors modifying drug action Dissociative anaesthesia Mechanism of anticoagulant action and uses of warfarin sodium Centrally acting skeletal muscle relaxants Sodium valproate Merits and demerits of using adrenaline along with local anaesthetic Mechanism of action of Digoxin in congestive cardiac failure Atypical antipsychotics Four indications for parenteral iron therapy Simvastatin
SHORT ANSWERS 13. 14. 15. 16. 17. 18. 19. 20. 21. 22. 23. 24. 25. 26. 27. 28. What is prodrug? Give two examples Uses of selective beta 2 agonists Rationale for preferring diazepam over phenobarbitone as sedative Drug induced Parkinsonism Rationale for use of Dopamine in cardiogenic shock Four adverse effects of phenothiazines Rationale for use of heparin in deep vein thrombosis What is succinylcholine apnoea? Nimodipine is used in subarachnoid haemorrhage Four salient features of clonidine Rationale for avoiding morphine in head injury What is zero order kinetics? Give two examples Mechanism of action of Cholinesterase reactivators Four salient features of Lignocaine What is Gene therapy? *****
16 X 2 = 32 Marks