Generic/ Brand name/ Drug Class Generic name: Promethazine hydrochloride Drug class: Antiemetic Antihistamine

Mode of Action

Dosage/Route/ Frequency Labor: 50 mg IM or IV in early stages

Indications

Contraindications

Side Effects

Nursing Interventions - Do not exceed the recommended dosage - take drug exactly as prescribed - avoid using alcohol - maintain fluid intake - Report dizziness, drowsiness, weakness tremors, etc.

Selectively blocks histamine 1 receptors

Diminising the effects of histamine on cells and the upper respiratory tract

- Prevention and control of nausea and vomiting associated with anesthesia and surgery - Adjunctive IV therapy with reduced amount of meperidine in surgical situations

- Contraindicated with hypersensitivity to antihistamines, vomiting of unknown cause, lactation. - Use cautiously with lower respiratory tract disorder

- drowsiness - dizziness - restlessness - respiratory depression - nausea and vomiting - weakness -tremors

Blocks cholinergic receptors in the vomiting center

Depresses the RAS

Generic/ Brand name/ Drug Class Generic name: Heparin Drug class: Anti coagulant

Mode of Action

Dosage/Route/ Frequency

Indications

Contraindications

Side Effects

Nursing Interventions

For general anti coagulation: IV loading dose of 5,000 units and then inhibits thrombus 10,000 to 20,000 and clot subcutaneously formation followed by 8,00010,000 units every 8 hr or 15,000-20,000 blocking the units every 12 hr formation of prothrombin to thrombin

inactivates factor Xa

- Prevention and treatment of venous thrombosis, pulmonary embolism and peripheral arterial embolism.

- Contraindicated with hypersensitivity to heparin; severe thrombocytopenia; Uncontrolled bleeding; any patient who cannot be monitored regularly with blood coagulation tests; labor and immediate postpartum period. - Use cautiously with pregnancy.

- severe headache - abdominal or lower back pain - chills - bleeding - bruising

- Adjust dose according to coagulation test results performed just before injection. - Always check compatibilities with other IV solutions.

- Use heparin lock thrombocytopenia needle to avoid repeated injections. - Give deep subcutaneous injections; do not give heparin by IM injection. - Do not give IM injections to patients on heparin therapy. Check for signs of bleeding; monitor blood tests.

blocking the formation of fibrinogen to fibrin

clotting process