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Diabetes Insipidus

Fever/nightsweats/weight loss
Polyuria (>2.5 liters/day)
Polydipsia
Nocturia
History of present Headache/neck stiffness
History of malignancy or pituitary surgery
illness Medications
Visual changes
Orthostatic symptoms
Seizures
Weakness

Nonspecific
Tachycardia
Diabetes Insipidus Physical Exam Orthostatic
JVD
Complete neurologic exam
Visual field defects

Urine osmolality < 200 mosm/kg


Urine specific gravity < 1.005
Initial BUN/Creatinine
UA
Serum sodium
Labs/Radiology Electrolytes
Glucose
Vasopressin challenge
Follow-up MRI brain
HCG
CXR

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