Scribd Logo
Upload

Welcome to Scribd!

  • Pathophysiology of Cerebral Schistosomiasis

    Uploaded by

    Risa Sol Arias
    164 views2 pages
    This document summarizes the predisposing and precipitating factors, pathophysiology, signs and symptoms, and management of cerebral schistosomiasis. The key predisposing factors are age, race (Filipino), and gender (more common in males). Precipitating factors include occupation as a farmer, poor treatment compliance, and living in an endemic area. The parasites penetrate the skin, travel to the lungs and liver to mature, then pair and produce eggs that migrate to the bladder or intestines. Eggs and worms can reach the brain, causing an immune response and granuloma formation that increases intracranial pressure and leads to seizures, headaches, and other neurological signs. Management includes antischistosomal

    Original Description:

    Copyright

    © Attribution Non-Commercial (BY-NC)

    Available Formats

    DOCX, PDF, TXT or read online from Scribd

    Did you find this document useful?

    Is this content inappropriate?

    Report this Document
    This document summarizes the predisposing and precipitating factors, pathophysiology, signs and symptoms, and management of cerebral schistosomiasis. The key predisposing factors are age, race (Filipino), and gender (more common in males). Precipitating factors include occupation as a farmer, poor treatment compliance, and living in an endemic area. The parasites penetrate the skin, travel to the lungs and liver to mature, then pair and produce eggs that migrate to the bladder or intestines. Eggs and worms can reach the brain, causing an immune response and granuloma formation that increases intracranial pressure and leads to seizures, headaches, and other neurological signs. Management includes antischistosomal

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as DOCX, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    Download as docx, pdf, or txt
    164 views2 pages

    Pathophysiology of Cerebral Schistosomiasis

    Uploaded by

    Risa Sol Arias
    This document summarizes the predisposing and precipitating factors, pathophysiology, signs and symptoms, and management of cerebral schistosomiasis. The key predisposing factors are age, race (Filipino), and gender (more common in males). Precipitating factors include occupation as a farmer, poor treatment compliance, and living in an endemic area. The parasites penetrate the skin, travel to the lungs and liver to mature, then pair and produce eggs that migrate to the bladder or intestines. Eggs and worms can reach the brain, causing an immune response and granuloma formation that increases intracranial pressure and leads to seizures, headaches, and other neurological signs. Management includes antischistosomal

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as DOCX, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    Download as docx, pdf, or txt
    of 2

    B.

    Diagram Predisposing Factors: *Age *Race - Filipino *Gender - common in male


    Precipitating Factors: *Occupation - farmer *Poor compliance to treatment *Living in schistosomiasis endemic area *Lifestyle

    cercariae penetrate human skin transform into a schistosomulae remain on the skin for 2 days travels into the lungs to mature reaches the liver after 8-10 days to further mature adult worms pair and produce eggs migrate to either intestines or bladder on the bladder Batson veins permits route to the CNS worms and eggs reach the brain they secrete antigens immune response formation of granuloma on the cerebrum increased ICP (intracranial pressure)
    S/Sx: 1. seizures 2. headache 3. visual abnormalities 4. Speech disturbances 5. Hemiparesis, hemiplegia, ataxia 6. Nystagmus 7. Sensory impairment

    Cerebral Schistosomiasis

    If treated: Nursing mgt: 1. Health teachings regarding prevention of reinfection, compliance to treatment, follow-up check-ups, and lifestyle modification.

    If not treated: DEATH

    Medical mgt: 1. Antischistosomal drugs such as Praziquantel to cause death of the adult worm, resulting in cessation of oviposition and thus a reduction in the inflammatory response. 2. Corticosteroids to diminish granulomatous inflammation and edema, thereby reducing the compression and destruction of the nervous tissue. 3. Anticonvulsant to prevent or stop/control ongoing seizures.

    Surgical mgt: Surgical excision is not encouraged.

    You might also like