Pathophysiology of Appendicitis (Ruptured)

Non-modifiable Age: 11-20 yrs old Gender: (Male-female=2:1) Hereditary: tumor opening in the of the appendix Modifiable Diet: People whose diet is low in fiber and rich in refined carbohydrates Infections: Gastrointestinal infections such as Amoebiasis, Bacterial Gastroenteritis,Mumps.

Obstruction of the appendix by fecalith(hardened stool), lymph node, tumor, foreign objects) Increase in pressure inside the appendix lumen that result to distention of appendix Impaired venous return causing hyperemia (improper O2 and nutrient supply) Normal bacteria found in appendix begin to invade (infect) the lining of the wall. Inflammatory Response body response to the bacterial invasion in the wall of appendix. Increased Immune complex (disease plus antibody) causes swelling of tissue resulting to inflammation of appendix S/S: Abdominal pain, fever, and increase swelling of appendix. Vomiting and loss of appetite. Appendectomy, Pain Medications

Pain - located @ RLQ,causing Guarding,Vomiting & loss of appetite

Inflammation and infection spread through the wall of the appendix causing death of tissue. The appendix ruptures due to increase pressure (Perforation)

Appendectomy with explore laparotomy

Perforation (formation of a hole in an organ), fecal materials exits to peritoneal cavity causing formation of abscesses (peri appendiceal abscess).Infection can spread throughout the abdomen (peritoneal cavity) Bacterial invasion of Peritoneal Cavity causing inflammation of the membrane that lines the abdomen peritoneum (Peritonitis) S/S: swelling of the abdomen, severe pain, and weight loss

Sepsis (the condition or syndrome caused by the presence of microorganisms or their toxins in the tissue or the bloodstream) Septicemia

If not threatened: Septic Shock S/S: decrease Blood pressure decrease bloodvolume

If Threatened: Strong antibiotic medication Fluid Volume replacement therapy RECOVERY

COMA DEATH