Population Genetics

(Gene pool)
(Hardy-Weinberg Equilibrium : HWE)

1.
2. mutation Natural selection

2 A p a q

p+q=1
p2 + 2pq +q2 = 1

p2 = AA, 2pq = Aa q2 = aa
heterozyqous 2

: Gene Gene

Ex 1 HWE 0.1
?

Ex 2 T 1,000 40 heterozygous
(Tt) HWE ?

Ex 3 ABO IA i 0.1 0.4 1,000

HWE

Ex 4 R
r 1,000 960 40
RR 640 Rr 320 R r

Ex 5 Rh (dd) 16 %
-

Ex 6 - 36 %
(aa)
1.

2. a

3. 500 Genotype
Homozygous

Ex 7 750 250
-

Ex 8 60
40

Ex 9 Galactosemia Autosome 40,000

1

Ex10
() 9 10,000

Ex 11 (b) (BB) 60 heterozygous 60

(bb) 80 random mating
F1 F2 %

Ex 12 500 (Aa) 160 (aa) 300

Ex 13 thalassemia 1%
%

Ex 14 ABO multiple alleles IA, IB I IA : IB : i

2 : 3: 15 500
AB A

Ex 15 1 100 heterozygous recessive