Professional Documents
Culture Documents
Pathophysiology: Precipitating Factor
Pathophysiology: Precipitating Factor
Predisposing factor Age > 40 year old Ethnicity (African-American, Hispanic /Latin, Asian- American) Family history of diabetes Male
Precipitating factor Obesity Inactive lifestyle Drugs (corticosteroids, beta blockers, and phenytoin) Faulty eating habit Viral infections Emotional stress Smoking, alcohol drinking HDL <35mg/dl Triglyceride-250 mg/dl or higher Impaired glucose tolerance
Decrease Glucose utilization Cell starvation Liver responds to demand of stained cells Stimulation of hunger mechanism
Weight loss
Hyperlipidemia
Glycogenolysis
Hunger Gluconeogenesis polyphagia Increase glucose level Weight loss Weakness and fatigue
Atherosclerosis
Changes in the vessel of lower extremities Intermittent claudication Decreased peripheral pulse
HYPERGLYCEMIA
Increased blood viscosity Increased osmotic pressure Decreased tissue perfusion Alters reabsorption of water in kidneys Kidney filtration mechanism is stressed Fluid loss
Polyuria
Glucosuria
Dehydration
NEPHROPATHY
Microalbuminuria Impaired delivered of blood component Heart Eyes CRF/ESRD Inadequate inflammation response Delayed wound healing Diminished myocardial oxygenation Blurring of vision Alters oncotic pressure
Chest pain
DIABETIC RETINOPATHY
PERIPHERAL NEUROPATHY
Nonproliferative
Prepoliferative
Proliferative
Burning sensation
Paresthesia
Microaneurysm
Numbness of extremities
Distorted vission
Decreases sensitivity
Unsteady gait
Diabetic ketoaciidosis
Abdominal pain
Poor appetite
Cardiac arrhythmia
Kussmauls respiration
Headache