A service of the U.S.

National Library of Medicine

My NCBI
and the National Institutes of Health
[Sign In] [Register]

All Databases PubMed Nucleotide Protein Genome Structure OMIM PMC Journals Books
Advanced Search
Search PubMed for Go
Clear
Limits Preview/Index History Clipboard Details

Display AbstractPlus Show 20 Sort By Send to

All: 1 Review: 0

1: Eur J Surg Oncol. 1992 Jun;18(3):275-81. Links

Potential protective effect of vitamin C on carcinogenesis caused by nitrosamine in drinking water: an Related Articles
experimental study on Wistar rats.
[The effect of subcutaneous nitrosamine injections on the origin of tumors of the
liver and their inhibition by vitamin C] [Ze ntr alb lChir. 1988]
Kessler H, Husemann B, Wagner W.
[Experimental development of carcinoma in rats caused by N-nitrosopiperidine
Surgical Hospital, University of Erlangen-Nürnberg, Germany. with vitamin C] [Ze ntr alb lChir. 1991]
NTP Toxicology and Carcinogenesis Studies of Pyridine (CAS No. 110-86-1) in
In an experiment with Wistar rats the question of whether oral vitamin C application has a protective effect in F344/N Rats, Wistar Rats, and B6C3F1[Nat
Mice (Drinking Water Studies).
l To xicol Pr ogr am TechRep Ser. 2000]
liver carcinogenesis caused by N-nitrosodiethylamine in drinking water (n = 104) was studied. When comparing
four groups (without carcinogen, with carcinogen and carcinogen plus vitamin C alternately and concomitantly) Dietary supplementation of the citrus antioxidant auraptene inhibits
significant statistical differences in the linear regression were noted. Ninety per cent of the rats developed N,N-diethylnitrosamine-induced rat hepatocarcinogenesis. [Oncol ogy. 2004]
hepatocellular carcinomas when only carcinogen was administered whereas the rate with additional Effects of green tea catechins in a rat multi-organ carcinogenesis model.
administration of vitamin C alternately and concomitantly was 68% and 55%, respectively. Without carcinogen [Ca rcinog enesis. 1993]
no tumour developed. The results suggest that vitamin C may delay the development of liver cancer upon oral
» See All...
administration of N-nitrosodiethylamine. The explanation for this fact is still hypothetical.
PMID: 1318851 [PubMed - indexed for MEDLINE] Patient Drug Information

Ascorbic Acid (Cecon® Drops, Cenolate® , Cevi-Bid® , ...) Ascorbic acid is used
to prevent and treat scurvy, a disease caused by a lack of vitamin C in the body.

Source: AHFS Consumer Medication Information

Recent Activity

Turn Off Clear

Potential protective effect of vitamin C on carcinogenesis caused by

nitrosamine in drinki...

Characterization of a new malignant human T-cell line (PFI-285) sensitive to

ascorbic acid...

Dietary vitamins A, C, and E and selenium as risk factors for cervical

cancer.

Display AbstractPlus Show 20 Sort By Send to

Write to the Help Desk
NCBI | NLM | NIH
Department of Health & Human Services
Privacy Statement | Freedom of Information Act | Disclaimer