GNIPST BULLETIN 2013

1118-1177-4796-9849-7562-5062

TO GROW AS A CENTRE OF EXCELLENCE IN THE FIELD OF PHARMACEUTICAL AND BIOLOGICAL SCIENCE

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17th MAY 2013

Volume No.: 25

Issue No.: 02

Vision

Contents

Message from GNIPST Letter to the Editor News Update Disease Outbreak News Health Awareness Forth Coming Events Drugs Update GNIPST Photo Gallery
For your comments/contribution OR For Back-Issues, mailto:gnipstbulletin@gmail.com

Campus News Students Section Editors Note Archive

1 EDITOR: Debabrata Ghosh Dastidar

GURU NANAK INSTITUTE OF PHARMACEUTICAL SCIENCE AND TECHNOLOGY

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MESSAGE FROM GNIPST

All the members of GNIPST are proud to publish the 25th Volume of GNIPST BULLETIN. This bulletin has successfully completed its twenty four months journey. We hope it has kept the readers updated of recent activities in pharmaceutical & biological sciences and also introduced them with the different activities of our esteemed institution. We are thankful to all of you for your great cooperation & support and are looking forward to the same in future.

LETTER TO THE EDITOR.

NEWS UPDATE

WORLD NO TOBACCO DAY: 31 MAY, 2013

Every year, on 31 May, WHO and partners mark World No Tobacco Day, highlighting the health risks associated with tobacco use and advocating for effective policies to reduce tobacco consumption. Tobacco kills nearly six million people each year, of which more than 600 000 are non-smokers dying from breathing second-hand smoke. The theme of this years campaign is "Ban tobacco advertising, promotion and sponsorship". Read more

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New Device Can Extract Human DNA With Full Genetic Data in Minutes (06
MAY 2013)

Engineers have created a device that can extract human DNA from fluid samples in a simpler, more efficient and environmentally friendly way than conventional methods. Read more

Ubiquitous Engineered Nanomaterials Can Cause Lung Inflammation: Substances Are Used in Everything from Paint to Sporting Equipment (06
MAY 2013)

Scientists have found that breathing ultrafine particles from a large family of materials that increasingly are found in a host of household and commercial products, from sunscreens to the ink in copy machines to super-strong but lightweight sporting equipment, can cause lung inflammation and damage. Read more Possible Treatment for Serious Blood Cancer

(06

MAY 2013)

A single antibody could be the key to treating multiple myeloma, or cancer of the blood, currently without cure or long-term treatment. New tests have shown that the antibody is able to destroy myeloma cells. Read more

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Endogenous Antibiotic Discovered in the Brain?

(06

MAY 2013)

Scientists have discovered that immune cells in the brain can produce a substance that prevents bacterial growth: namely itaconic acid. Until now, biologists had assumed that only certain fungi produced itaconic acid. Scientists have now shown that even so-called microglial cells in mammals are also capable of producing this acid. Read more Brain Anatomy of Dyslexia Is Not the Same in

Men and Women, Boys and Girls (08

MAY 2013)

Using MRI, neuroscientists have found significant differences in brain anatomy when comparing men and women with dyslexia to their non-dyslexic control groups. Their study is the first to directly compare brain anatomy of females with and without dyslexia. Read
more

Biosensor

That Detects Antibiotic Resistance

Brings Us One Step Closer to Fighting Superbugs. (08

MAY 2013)

New research demonstrates how a biosensor can detect antibiotic resistance in bacteria. This new technology is a preliminary step in identifying and fighting superbugs, a major public health concern
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that has led to more deaths than AIDS in the United States in recent years. Read more Using Bacteria to Stop Malaria (09
MAY 2013)

Mosquitoes are deadly efficient disease transmitters. New research however, demonstrates that they also can be part of the solution for preventing diseases such as malaria. Read more 'Magic Bullet Nanomedicine Developed for Acute

Lung Injury (14

MAY 2013)

Researchers have devised a magic bullet nanomedicine which could become the first effective treatment for Acute Lung Injury or ALI, a condition affecting 20 per cent of all patients in intensive care. Read more Vitamin C Does Not Lower Uric Acid Levels in

Gout Patients, Study Finds (16

MAY 2013)

Despite previous studies touting its benefit in moderating gout risk, new research reveals that vitamin C, also known ascorbic acid, does not reduce uric acid (urate) levels to a clinically significant degree in patients with established gout. Vitamin C supplementation, alone or in combination with allopurinol, appears to have a weak effect on lowering uric acid levels in gout patients, according to the results of a new study. Read more

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HEALTH AWARENESS

TOBACCO
Leading cause of death, illness and impoverishment The tobacco epidemic is one of the biggest public health threats the world has ever faced. It kills nearly 6 million people a year of whom more than 5 million are from direct tobacco use and more than 600 000 are nonsmokers exposed to second-hand smoke. Approximately one person dies every six seconds due to tobacco and this accounts for one in 10 adult deaths. Up to half of current users will eventually die of a tobacco-related disease. Nearly 80% of the more than one billion smokers worldwide live in lowand middle-income countries, where the burden of tobacco-related illness and death is heaviest. Tobacco users who die prematurely deprive their families of income, raise the cost of health care and hinder economic development. In some countries, children from poor households are frequently employed in tobacco farming to provide family income. These children are especially vulnerable to "green tobacco sickness", which is caused by the nicotine that is absorbed through the skin from the handling of wet tobacco leaves. Gradual killer

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17-05-2013 Because there is a lag of several years between when people start using tobacco and when their health suffers, the epidemic of tobacco-related disease and death has just begun. Tobacco caused 100 million deaths in the 20th century. If current trends continue, it may cause about one billion deaths in the 21st century. Unchecked, tobacco-related deaths will increase to more than eight million per year by 2030. More than 80% of those deaths will be in low- and middle-income countries. Surveillance is key Good monitoring tracks the extent and character of the tobacco epidemic and indicates how best to tailor policies. Only fifty-nine countries, representing under half of the world's population, monitor tobacco use by repeating nationally representative youth and adult surveys at least once every five years. Second-hand smoke kills Second-hand smoke is the smoke that fills restaurants, offices or other enclosed spaces when people burn tobacco products such as cigarettes, bidis and water pipes. There are more than 4000 chemicals in tobacco smoke, of which at least 250 are known to be harmful and more than 50 are known to cause cancer. There is no safe level of exposure to second-hand tobacco smoke.

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17-05-2013 In adults, second-hand smoke causes serious cardiovascular and respiratory diseases, including coronary heart disease and lung cancer. In infants, it causes sudden death. In pregnant women, it causes low birth weight. Almost half of children regularly breathe air polluted by tobacco smoke in public places. Over 40% of children have at least one smoking parent. Second-hand smoke causes more than 600 000 premature deaths per year. In 2004, children accounted for 28% of the deaths attributable to secondhand smoke. Every person should be able to breathe smoke-free air. Smoke-free laws protect the health of non-smokers, are popular, do not harm business and encourage smokers to quit. Under 11% of the world's population are protected by comprehensive national smoke-free laws. The number of people protected from second-hand smoke more than doubled to 739 million in 2010 from 354 million in 2008. Tobacco users need help to quit Studies show that few people understand the specific health risks of tobacco use. For example, a 2009 survey in China revealed that only 38% of smokers knew that smoking causes coronary heart disease and only 27% knew that it causes stroke.
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Among smokers who are aware of the dangers of tobacco, most want to quit. Counselling and medication can more than double the chance that a smoker who tries to quit will succeed. National comprehensive health-care services supporting cessation are available in only 19 countries, representing 14% of the world's population. There is no cessation assistance in 28% of low-income countries and 7% of middle-income countries. Picture warnings work Hard-hitting anti-tobacco advertisements and graphic pack warnings especially those that include pictures reduce the number of children who begin smoking and increase the number of smokers who quit. Graphic warnings can persuade smokers to protect the health of nonsmokers by smoking less inside the home and avoiding smoking near children. Studies carried out after the implementation of pictorial package warnings in Brazil, Canada, Singapore and Thailand consistently show that pictorial warnings significantly increase people's awareness of the harms of tobacco use. Mass media campaigns can also reduce tobacco consumption, by influencing people to protect non-smokers and convincing youths to stop using tobacco.

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17-05-2013 Just 19 countries, representing 15% of the world's population, meet the best practice for pictorial warnings, which includes the warnings in the local language and cover an average of at least half of the front and back of cigarette packs. No low-income country meets this best-practice level. Forty-two countries, representing 42% of the worlds population, mandate pictorial warnings. More than 1.9 billion people, representing 28% of the world's population, live in the 23 countries that have implemented at least one strong antitobacco mass media campaign within the last two years. Ad bans lower consumption Bans on tobacco advertising, promotion and sponsorship can reduce tobacco consumption. A comprehensive ban on all tobacco advertising, promotion and sponsorship could decrease tobacco consumption by an average of about 7%, with some countries experiencing a decline in consumption of up to 16%. Only 19 countries, representing 6% of the worlds population, have comprehensive national bans on tobacco advertising, promotion and sponsorship. Around 38% of countries have minimal or no restrictions at all on tobacco advertising, promotion and sponsorship. Taxes discourage tobacco use

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17-05-2013 Tobacco taxes are the most effective way to reduce tobacco use, especially among young people and poor people. A tax increase that increases tobacco prices by 10% decreases tobacco consumption by about 4% in high-income countries and by up to 8% in low- and middle-income countries. Only 27 countries, representing less than 8% of the world's population, have tobacco tax rates greater than 75% of the retail price. Tobacco tax revenues are on average 154 times higher than spending on tobacco control, based on available data.

DISEASE OUTBREAK NEWS

FORTHCOMING EVENTS
AICTE Sponsored National Seminar on "EMERGING TRENDS AND INNOVATIONS IN DRUG DELIVERY AND PHARMACEUTICAL SCIENCES". Date: 19th May. 2013. Venue: Columbia Institute of Pharmacy, Raipur, CG, India Registration form

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DRUGS UPDATES
FDA approves Simponi to treat ulcerative colitis

(15

MAY 2013)

The U.S. FDA approved a new use for Simponi (golimumab) injection to treat adults with moderate to severe ulcerative colitis. Read more FDA approves new drug for advanced prostate

cancer (15

MAY 2013)

Xofigo (radium Ra 223 dichloride) to treat men with symptomatic late-stage (metastatic) castration-resistant prostate cancer that has spread to bones but not to other organs. It is intended for men whose cancer has spread after receiving medical or surgical therapy to lower testosterone. Read more.

CAMPUS NEWS
JOB OPPOURTUNITY There is vacancy for the post of Medical Representative in Eisai Pharmaceuticals India Pvt. Ltd. The interested B.Pharm. pass out students are required to contact Mr. Abir Koley (8017445495) immediately.
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STUDENTS SECTION
WHO CAN ANS WER FIRS T???

() Arne Larsson was famous as a first patient of which implanted device? () Albert Ladenburg in 1980 isolated which alkaloid?
Answer of Previous Issue Question:

A) Prednisone

B) Methotrexate

Send your thoughts/ Quiz/Puzzles/games/writeups or any other contributions for Students Section & answers of this Section at EDITORS NOTE I am very happy to publish the 2nd issue of 25th Volume of GNIPST BULLETIN. It is my great pleasure to introduce you to the newly launched facebook account GNIPST bulletin. You are cordially invited to add this account to your friend list. The current issues will also be directly available on facebook. I would like to convey my thanks to all the GNIPST members and the readers for their valuable comments, encouragement& supports.
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gnipstbulletin@gmail.com

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Special thanks to Dr. Prerona Saha for her advice; Mr. Soumya Bhattacharya, for his contribution in students section. It would be my great pleasure to receive the contributions, suggestions & feedback from your desk for further upliftment of this deliberation GNIPST BULLETIN.

ARCHIVE The general body meeting of APTI, Bengal Branch has been conducted at GNIPST on 15th June, 2012. The programme started with a nice presentation by Dr. Pulok Kr. Mukherjee, School of Natural Products, JU on the skill to write a good manuscript for publication in impact journals. It was followed by nearly two hour long discussion among more than thirty participants on different aspects of pharmacy education. Five nonmember participants applied for membership on that very day. GNIPST is now approved by AICTE and affiliated to WBUT for conducting the two years post graduate course (M.Pharm) in

PHARMACOLOGY. The approved number of seat is 18.

The number of seats in B.Pharm. has been increased from 60 to 120. 2nd World Congress on Ga-68 (Generators and Novel Radiopharmaceuticals), Molecular Imaging (PET/CT), Targeted Radionuclide Therapy, and Dosimetry (SWC-2013) : On the Way to Personalized Medicine
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Dates 28 Feb 2013 02 Mar 2013 Location: Chandigarh, India.Details.

AICTE has sanctioned a release of grant under Research Promotion Scheme (RPS) during the financial year 201213to GNIPST as per the details below: a. Beneficiary Institution: Guru Nanak Institution of Pharmaceutical Science & Technology. b. Principal Investigator: Dr. Lopamudra Dutta. c. Grant-in-aid sanctioned: Rs. 16,25000/- only d. Approved duration: 3 years e. Title of the project: Screening and identification of potential medicinal plant of Purulia &Bankura districts of West Bengal with respect to diseases such as diabetes, rheumatism, Jaundice, hypertension and developing biotechnological tools for enhancing bioactive molecules in these plant.

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