GNIPST BULLETIN 2013

Admission in Biotechnology (M.Sc) and Genetics (M.Sc) is going on

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TO GROW AS A CENTRE OF EXCELLENCE IN THE FIELD OF PHARMACEUTICAL AND BIOLOGICAL SCIENCE

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9th August, 2013

Volume No.: 28

Issue No.: 01

Vision

Contents
Message from GNIPST Letter to the Editor News Update Health awareness Disease Outbreak News Forth Coming Events Drugs Update GNIPST Photo Gallery
For your comments/contributionOR

Campus News Students Section Editors Note Archive

For Back-Issues,
mailto:gnipstbulletin@gmail.com

1 EDITOR:Soumya Bhattacharya

GURU NANAK INSTITUTE OF PHARMACEUTICAL SCIENCE AND TECHNOLOGY

09-08-2013

MESSAGE FROM GNIPST

GNIPST BULLETIN is the official publication of Guru Nanak Institute of Pharmaceutical Science & Technology. All the members of GNIPST are proud to publish the 28th Volume of GNIPST BULLETIN. Over the last two years this bulletin updating readers with different scientific, cultural or sports activities of this prestigious institute and promoting knowledge of recent development in Pharmaceutical and Biological Sciences. Students section is informing readers about some curious facts of drug discovery, science, sports and other relevant fields. We look forward to seeing your submission and welcome comments and ideas you may have.

LETTER TO THE EDITOR.

NEWS UPDATE

World Hepatitis day,2013

(28th July, 2013)

The World Hepatitis Day was observed on 28th July globally. Every year on 28 July, WHO and partners mark World Hepatitis Day to increase the awareness and understanding of viral hepatitis and the diseases that it causes. The theme of this year is "This is hepatitis. Know it. Confront it." Hepatitis viruses A, B, C, D and E can cause acute and chronic infection and inflammation of the liver that can lead to cirrhosis and liver cancer. These viruses constitute a major global health risk with around 240 million people being chronically infected with hepatitis B and around 150 million people chronically infected with hepatitis C. World Hepatitis Day provides an opportunity to focus on specific actions, such as:

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strengthening prevention, screening and control of viral hepatitis and its related diseases; increasing hepatitis B vaccine coverage and integration of the vaccine into national immunization programmes; coordinating a global response to viral hepatitis. Read more
(1st August, 2013)

World Breastfeeding Week

World Breastfeeding Week is celebrated every year from 1 to 7 August in more than 170 countries to encourage breastfeeding and improve the health of babies around the world. It commemorates the Innocenti Declaration made by WHO and UNICEF policy-makers in August 1990 to protect, promote and support breastfeeding. Breastfeeding is the best way to provide newborns with the nutrients they need. WHO recommends exclusive breastfeeding until a baby is six months old and continued breastfeeding with the addition of nutritious complementary foods for up to two years or beyond. Read more

Breastfed children are less likely to develop adhd later in life (22nd July, 2013)
Researchers from Tel Aviv University have shown that breastfeeding may also help protect against Attention Deficit/Hyperactivity Disorder (ADHD), the most commonly diagnosed neurobehavioral disorder in children and adolescents. Read more

Linked between Psoriasis and other medical condition established

(7th August, 2013)

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Recent study revealed that that people with psoriasis had higher rates of chronic lung disease, diabetes, mild liver disease, heart attack, peptic ulcer, peripheral vascular disease, kidney disease and rheumatologic disease. Read more

High blood sugar levels tied to small increases in dementia risk (7th August , 2013)
Elevated blood sugar levels, even among people who don't have diabetes, are associated with an increased risk for dementia, a new study shows. The effect was very subtle, however, suggesting that higher blood sugar levels may be more of a nudge toward memory loss than a shove. Read more

Obese kids more likely to have asthma, with worse symptoms (7th August, 2013)
Overweight and obese kids are more likely to struggle with asthma than kids of normal weight, according to a new review of more than 623,000 children.Researchers found that children carrying extra weight are between 1.16 to 1.37 times more likely to develop asthma than normal-weight kids, with the risk growing as their body-mass index Read more

Gold 'nanoprobes' hold the key to treating killer diseases (7th August, 2013)
Researchers at the University of Southampton, in collaboration with colleagues at the University of Cambridge, have developed a technique to help treat fatal diseases more effectively. Dr Sumeet Mahajan and his group at the Institute for Life Sciences at Southampton are using gold nanoprobes to identify different types

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of cells, so that they can use the right ones in stem cell therapies. Read more

Genes that drive brain cancer revealed

2013)

(7th August,

A team of researchers at the Herbert Irving Comprehensive Cancer Center at Columbia University Medical Center has identified 18 new genes responsible for driving glioblastoma multiforme, the most common and most aggressive form of brain cancer in adults. Read more

HEALTH AWARENESS

Salmonella-WHO Key Facts

Key facts

Salmonellosis, is one of the most common and widely distributed foodborne diseases, with tens of millions of human cases occurring worldwide every year. Most cases of salmonellosis are mild, however, sometimes people die from salmonellosis. The severity of the disease may depend on host factors and the strain of Salmonella. Since the beginning of the 1990s, Salmonella strains which are resistant to a range of antimicrobials have emerged and are now a serious public health concern. Basic food hygiene practices, such as "cook thoroughly", is recommended as a preventive measure against salmonellosis. Overview Salmonellosis is one of the most common and widely distributed foodborne diseases and is caused by the bacteria Salmonella. It is estimated that tens of millions of human cases occur worldwide
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every year and the disease results in more than hundred thousand deaths. For Salmonella species, over 2 500 different strains (called "serotypes" or "serovars") have been identified to date. Salmonella is a ubiquitous and hardy bacteria that can survive several weeks in a dry environment and several months in water. While all serotypes can cause disease in humans, a few are host specific and can reside in only one or a few animal species, for example, Salmonella Dublin in cattle; and Salmonella Choleraesuis in pigs. When these particular serotypes cause disease in humans, it is often invasive and can be life-threatening. Most serotypes, however, are present in a wide range of hosts. Typically, such strains cause gastroenteritis, which is often uncomplicated and does not need treatment, but can be severe in the young, the elderly and patients with weakened immunity. This group features Salmonella Enteritidis and Salmonella Typhimurium, the two most important serotypes of salmonellosis transmitted from animals to humans in most parts of the world. The disease Salmonellosis is a disease caused by the bacteria Salmonella. It is usually characterized by acute onset of fever, abdominal pain, diarrhoea, nausea and sometimes vomiting. The onset of disease symptoms occurs 6 - 72 hours (usually 12-36 hours) after ingestion of Salmonella, and illness lasts 2-7 days. Symptoms of salmonellosis are relatively mild and patients will make a recovery without specific treatment in most cases. However, in some cases, particularly in the very young and in the elderly patients, the associated dehydration can become severe and life-threatening. Although large Salmonella outbreaks usually attract media attention, 60 to 80% of all salmonellosis cases are not recognized as part of a known outbreak and are classified as sporadic cases, or are not diagnosed as such at all. Sources and transmission

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Salmonella bacteria are widely distributed in domestic and wild animals. They are prevalent in food animals such as poultry, pigs, cattle; and in pets, including cats and dogs, birds and reptiles such as turtles. Salmonella can pass through the entire food chain from animal feed, primary production, and all the way to households or food-service establishments and institutions. Salmonellosis in humans is generally contracted through the consumption of contaminated food of animal origin (mainly eggs, meat, poultry and milk), although other foods, including green vegetables contaminated by manure, have been implicated in its transmission. Person-to-person transmission through the faecal-oral route can also occur. Human cases also occur where individuals have contact with infected animals, including pets. These infected animals often do not show signs of disease. Treatment Treatment in severe cases is symptomatic, electrolyte replacement (to provide electrolytes, such as sodium, potassium and chloride ions, lost through vomiting and diarrhoea) and rehydration. Routine antimicrobial therapy is not recommended for mild or moderate cases in healthy individuals. This is because antimicrobials may not completely eliminate the bacteria and may select for resistant strains, which subsequently can lead to the drug becoming ineffective. However, health risk groups such as infants, the elderly and immunocompromised patients may need to receive antimicrobial therapy. Antimicrobials are also administered if the infection spreads from the intestine to other body parts. Because of the global increase of antimicrobial resistance, treatment guidelines should be reviewed on a regular basis taking into account the resistance pattern of the bacteria. Prevention methods

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Prevention requires control measures at all stages of the food chain, from agricultural production, to processing, manufacturing and preparation of foods in both commercial establishments and at home. Preventive measures for Salmonella in the home are similar to those used against other foodborne bacterial diseases (see "Recommendations for food handlers" below). Some animals can also pass the bacteria directly to people. The contact between infants/young children and pet animals (cats, dogs, turtles etc.) needs careful supervision. National/regional surveillance systems are important means to detect and respond to salmonellosis and other enteric infections in early stages, and thus to prevent them from further spreading. Recommendations for the public and travellers

Ensure food is properly cooked and still hot when served. Avoid raw milk and products made from raw milk. Drink only pasteurized or boiled milk. Avoid ice unless it is made from safe water. When the safety of drinking water is questionable, boil it or if this is not possible, disinfect it with a reliable, slow-release disinfectant agent (usually available at pharmacies). Wash hands thoroughly and frequently using soap, in particular after contact with pets or farm animals, or after having been to the toilet. Wash fruits and vegetables carefully, particularly if they are eaten raw. If possible, vegetables and fruits should be peeled. When travelling, refer to WHO's brochure A guide on safe food for travellers. Recommendations for food handlers Both professional and domestic food handlers should be vigilant while preparing food and should observe hygienic rules of food preparation.

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1. 2. 3. 4. 5.

Professional food handlers who suffer from fever, diarrhoea, vomiting or visible infected skin lesions should report to their employer immediately. The WHO Five Keys to Safer Food serve as the basis for educational programmes to train food handlers and educate consumers. They are especially important in preventing food poisoning. The Five Keys are: Keep clean. Separate raw and cooked. Cook thoroughly. Keep food at safe temperatures. Use safe water and raw materials. Recommendations for producers of fruits and vegetables The WHO Five Keys to Growing Safer Fruits and Vegetables3 is an educational manual for rural workers, including small farmers who grow fresh fruits and vegetables for themselves, their families and for sale in local market. It provides them with key practices to prevent microbial contamination of fresh produces during planting, growing, harvesting and storing. The Five keys practices are: Practice good personal hygiene. Protect fields from animal faecal contamination. Use treated faecal waste. Evaluate and manage risks from irrigation water. Keep harvest and storage equipment clean and dry. WHO response WHO promotes the strengthening of food safety systems, promoting good manufacturing practices and educating retailers and consumers about appropriate food handling and avoiding contamination. Education of consumers and training of food handlers in safe food handling is one of the most critical means to prevent foodborne illnesses including salmonellosis. WHO strengthens and enhances the capacities of national and regional laboratories in the surveillance of Salmonella, the other major foodborne pathogens and antimicrobial resistance
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in Salmonella and Campylobacter from humans, food and animals through the network called Global Foodborne Infections Network (GFN) . WHOs main tool to assist Member States in surveillance, coordination and response to outbreaks is the use of the International Network of Food Safety Authorities (INFOSAN) . which links national authorities in Member States in charge of managing food safety events. This network is managed jointly by FAO and WHO.

DISEASE OUTBREAK NEWS

Middle

East

Respiratory

Syndrome

coronavirus

(MERS-CoV) (1st August, 2013)

WHO has been informed of an additional three laboratory-confirmed cases of Middle East respiratory syndrome coronavirus (MERS-CoV) infection in Saudi Arabia. Read more

FORTHCOMING EVENTS

The 2nd Pharm. Tech IAPST International Conference on "New insights into
diseases and recent therapeutic approaches" from 17th to 19th January 2014 in Kolkata, India. Read more

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DRUGS UPDATES

FDA Approves Injectafer for Iron Deficiency Anemia

Injectafer (ferric carboxymaltose injection) has received U.S. Food and Drug Administration (FDA) approval. Injectafer is a parenteral iron replacement product used for the treatment of iron deficiency anemia (IDA) in adult patients who have intolerance to oral iron or have had an unsatisfactory response to oral iron. Injectafer is also indicated for iron deficiency anemia in adult patients with non-dialysis dependent chronic kidney disease (NND-CKD). Read more

FDA

permits for

marketing bacteria

of

first

U.S. to

test of the

labeled

simultaneous and
(25th July)

detection

tuberculosis

resistance

antibiotic rifampin

The U.S. Food and Drug Administration today allowed marketing of the Xpert MTB/RIF Assay, the first FDA-reviewed test that can simultaneously detect bacteria that cause tuberculosis (TB) and determine if the bacteria contain genetic markers that makes them resistant to rifampin, an important antibiotic for the treatment of TB. Read more

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CAMPUS NEWS Azalea (exotic flower ) , the fresher welcome programme for
newcomers of GNIPST in the session 2013-14 was held on 8th August in GNIPST Auditorium One day seminar cum teachers development programme for school teachers on the theme of Recent Trends of Life Sciences in Higher Education organized by GNIPST held on 29th June, 2013 at GNIPST auditorium. The programme was inaugurated by Prof . Asit Guha, Director of JIS Group, Mr. U.S. Mukherjee, Dy Director of JIS Group and Dr. Abhijit Sengupta, Director cum Principal of GNIPST with lamp lighting. The programme started with an opening song performed by the B.Pharm students of this institute. The seminar consists of a series of lectures, video presentations and poster session. On the pre lunch session 4 lectures were given by Dr. Lopamudra Dutta, Mr. Debabrata Ghosh Dastidar, Ms. Swati Nandy and Ms. Tamalika Chakraborty respectively. On their presentation the speakers enlighten the recent development of Pharmacy, Genetics and Microbiology and their correlation with Life Sciences. On the post lunch session, Ms. Saini Setua and Ms. Sanchari Bhattacharjee explained the recent development and career opportunities in Biotechnology and Hospital Management. The programme was concluded with valedictory session and certificate distribution. About 50 Higher secondary school teachers from different schools of Kolkata and North& South 24 Parganas district of West Bengal participated in this programme. A good interactive session between participants and speakers was observed in the seminar. The seminar was a great success with the effort of faculties, staffs and students of our Institute. It was a unique
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discussion platform for school teachers and professional of the emerging and newer branches of Life Science.

The following B.Pharm. final year students have qualified, GPAT2013. We congratulate them all.

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WHO CAN ANS WER FIRS T????

Which pathophysiological term is derived from Greek word falling from? Which pathophysiological term is derived from Greek word act of killing?
A) B.S. Blumberg B)Liver transplantation
Answer of Previous Issues Questions:

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Send your thoughts/ Quiz/Puzzles/games/writeups or any other contributions for Students Section& answers of this Section atgnipstbulletin@gmail.com

EDITORS NOTE I am proud to publish the 1st issue of 28th Volume of GNIPST BULLETIN.GNIPST BULLETIN now connected globally through facebook account GNIPST bulletin I want to convey my thanks to all the GNIPST members and the readers for their valuable comments, encouragement and supports. I am thankful to Dr. Abhijit Sengupta, Director of GNIPST for his valuable advice and encouragement. Special thanks to Dr. Prerona Saha and Mr. Debabrata Ghosh Dastidar for their kind co-operation and technical supports. An important part of the improvement of the bulletin is the contribution of the readers. You are invited to send in your write ups, notes, critiques or any kind of contribution for the forthcoming special and regular issue.

ARCHIVE The general body meeting of APTI, Bengal Branch has been conducted at GNIPST on 15th June, 2012. The program started with a nice presentation by Dr. Pulok Kr. Mukherjee, School of Natural Products, JU on the skill to write a good manuscript for publication in impact journals. It was followed by nearly two hour long discussion among
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more than thirty participants on different aspects of pharmacy education. Five nonmember participants applied for membership on that very day. GNIPST is now approved by AICTE and affiliated to WBUT for conducting the two years post graduate course (M.Pharm) in PHARMACOLOGY. The approved number of seat is 18. The number of seats in B.Pharm. has been increased from 60 to 120. AICTE has sanctioned a release of grant under Research Promotion Scheme (RPS) during the financial year 2012-13to GNIPST as per the details below: a. Beneficiary Institution: Guru Nanak Institution of Pharmaceutical Science & Technology. b. Principal Investigator: Dr. LopamudraDutta. c. Grant-in-aid sanctioned:Rs. 16,25000/- only d. Approved duration: 3 years e. Title of the project: Screening and identification of potential medicinal plant of Purulia & Bankura districts of West Bengal with respect to diseases such as diabetes, rheumatism, Jaundice, hypertension and developing biotechnological tools for enhancing bioactive molecules in these plants.

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