1

Amino Acids: Name, pKas, Structure, & Polarity (Classification)

Full Name 3-L 1-L Structure Polarity -COOH -NH3+ pKa pKa R-group pKa Codons R-Group Structure

Alanine

Ala

Non-polar
(hydrophobic)

2.4

9.7

GCU GCC GCA GCG

Isoleucine

Ile

Non-polar
(hydrophobic)

2.4

9.7

AUU AUC AUA

Leucine

Leu

Non-polar
(hydrophobic)

2.4

9.6

CUU CUC CUA CUG

AUG

Methionine

Met

Non-polar
(amphipathic)

2.3

9.2

(Start Codon)

Amino Acids: Name, pKas, Structure, & Polarity (Classification)

Phenylalanine

Phe

Non-polar
(hydrophobic)

1.8

9.1

UUU UUC

Proline

Pro

Non-polar
(hydrophobic) 2.1 10.6

CCU CCC CCA CCG

UGG

Tryptophan

Trp

Non-polar
(amphipathic) 2.4 9.4

Valine

Val

Non-polar
(hydrophobic)

2.3

9.6

GUU GUC GUA GUG

Amino Acids: Name, pKas, Structure, & Polarity (Classification)

Asparagine

Asn

Polar uncharged

2.0

8.8

AAU AAC

Cysteine

Cys

Polar uncharged

1.7

10.8

8.3

UGU UGC

Glutamine

Gln

Polar uncharged

2.2

9.1

CAA CAG

Glycine

Gly

Polar Uncharged
*Hydrophobic

2.3

9.6

GGU GGC GGA GGG -UCU -UCC -UCA -UCG *AGU *AGC

Serine

Ser

Polar uncharged

2.2

9.2

~ 13

Amino Acids: Name, pKas, Structure, & Polarity (Classification)

Threonine

Thr

Polar uncharged

2.6

10.4

~ 13

ACU ACC ACA ACG

Tyrosine

Tyr

Polar uncharged

2.2

9.1

10.1

UAU UAC

Aspartic Acid

Asp

Acidic

2.1

9.8

3.9

GAU GAC

Glutamic Acid

Glu

Acidic

2.2

9.7

4.3

CAA CAG

Amino Acids: Name, pKas, Structure, & Polarity (Classification)

Arginine

Arg

Basic

2.2

9.0

12.5

AGA AGG

Histidine

His

Basic

1.8

9.2

6.0

CAU CAC

Lysine

Lys

Basic
(amphipathic) 2.2 9.0 10.5

AAA AAG

Stop Codon

UAA

UAG

UGA