DRUG STUDY

Generic Name: Ibuprofen Brand name: Classification: Dosage: Advil, Children's Advil/Motrin, Medipren, Motrin, Nuprin, PediaCare Fever etc. Analgesics, NSAID, Propionic acide derivative Fever: adults: 200 to 400 mg P.O q4 to 6 hours, for no longer than 3 days. Max. daily dose is 1.2 g Children: ages 6 months to 12 years: if childs temp. is below 39.2C give 5 mg/kg P.O q6 to 8 hours Mode of Action: May inhibit prostaglandin synthesis, to produce anti-inflammatory, analgesic, and antipyretic effects

Indication: Relief of mild to moderate pain.Fever reduction, Post surgery, Headache & musculoskeletal pain, Soft tissue inflammation. Inlcuding juvenile RA Contraindication: C/I with allergy to ibuprofen, salicylates, or other NSAIDS (more common in pts with rhinitis, asthma, chronic iticuria nasal polyps. Advanced kidney and liver disease. Asthma; Active GI bleeding Ibuprofen may increase the blood levels of lithium (Eskalith) by reducing the excretion of lithium by the kidneys. Increased levels of lithium may lead to lithium toxicity. Ibuprofen may reduce the blood pressure-lowering effects of drugs that are given to reduce blood pressure. rash,ringing in the ears, headaches, dizziness, drowsiness, abdominal pain,nausea, diarrhea, constipation and heartburn. Tell patient to takewith meals or milk toreduce adverse GIreactions. Note: Drug is availableat OTC. Instructpatient not to exceed1.2 g daily, not to giveto chidren younger than age 12, and notto take for extendedperiods ( longer than 3days for fever or longer than 10 daysfor pain) withoutconsulting presciber. Tell patient that fulltherapeutic effect for arthritis may bedelayed for 2 to 4weeks. Although painrelief occurs at lowdosage levels,inflammation doesntimprove at dosagesless than 400 mg q.i.d. Teach patient to watchfor and report toprescriber immediatelysigns and symptomsof GI bleeding,including blood invomit, urine, or stool or coffee ground vomit,and black, tarry stool

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Guppy Fish Proven to Be Cheap, Effective Tool in Fight Against Dengue Fever Sep. 12, 2013 Larvae-eating guppy fish can help combat the spread of dengue, a mosquito-borne illness giving rise to hundreds of thousands of severe cases including 20,000 deaths worldwide every year, according to a trial study by the Governments of Cambodia and the Lao People's Democratic Republic (Lao PDR) with the support of the Asian Development Bank (ADB) and the World Health Organization (WHO). emergency response measures. Currently there is still no vaccine or specific medicine to treat this viral disease. Around 2.5 billion people worldwide are at risk of contracting dengue, more than 70% of whom live in Asia and the Pacific. The threat of exposure to dengue-carrying mosquitoes is rising with uncontrolled urbanization and a surge in the use of nonbiodegradable packaging, which can act as a water reservoir for dengue mosquito breeding. Dengue is spread by a specific mosquito that breeds readily in standing water, such as found in storage containers, flower pots and discarded tires. The guppies are particularly effective in these settings. Convincing communities to accept fish in their water containers was a key element of the project. The trial showed that guppies do not harm water quality and can survive on microscopic organic material in the absence of mosquito larvae. At the project close in Cambodia, about 88% of the storage containers contained guppies, with the figure at 76% in Lao PDR. "The project was successful in mobilizing communities with widespread grassroots participation, and high levels of acceptance of fish as an effective way of reducing the spread of dengue," said Dr. Eva Christophel, a WHO specialist in vectorborne diseases. "This project was an important contribution to WHO's efforts to develop a toolkit of different community-based methods to prevent and reduce the magnitude of dengue transmission."
http://www.sciencedaily.com/releases/2013/09 /130912091656.htm

"This is a low-cost, year-round, safe way of reducing the spread of dengue in which the whole community can participate," said ADB health specialist Gerard Servais. "It offers a viable alternative to using chemicals and can reduce the scale of costly emergency response activities to contain epidemics." The community-based project, conducted in two districts in Cambodia and the Lao PDR from 2009 to 2011, resulted in a sharp decline in mosquito larvae in water storage tanks after the tiny fish were introduced. Guppies eat larvae that grow into mosquitoes, which in turn bite humans and transmit dengue. Dengue causes severe joint and muscle pain, headache, high fever and rashes and is fatal in a small proportion of cases, in particular if not diagnosed and treated early. Outbreaks of the illness not only affect families with sudden health care costs and loss of incomes for adults put out of work, but also impact health services, businesses and tourism, straining government budgets due to unplanned spending on large-scale

Nursing Diagnosis: Hyperthermia related to the process of dengue virus infection. Goal: Normal body temperature Outcomes: Body temperature between 36-37 0 C Muscle pain disappeared

Goal: Normal body temperature Expected outcomes: The body temperature between 36-37 0C, muscle pain disappeared. Intervention: 1. Assess the patient's body temperature Rational: find an increase in body temperature, facilitate intervention. 2. Give warm compresses Rational: reduce heat to heat transfer by conduction. Warm water is slowly control the heat removal without causing hypothermia or shivering. 3. Provide / encourage patients to drink plenty of 1500-2000 cc / day (as tolerated). Rationale: To replace fluids lost due to evaporation. 4. Instruct patient to wear clothes that are thin and easy to absorb sweat. Rationale: To provide a sense of comfort and wear thin easily absorbs sweat and does not stimulate an increase in body temperature. 5. Observation intake and output, vital signs (temperature, pulse, blood pressure) once every 3 hours or as indicated. Rationale: Early Detect hydrated and knowing fluid and electrolyte balance in the body. Vital Signs is a reference to determine the patient's general condition. 6. Collaboration: intravenous fluid and drug delivery according to the program. Rationale: Proper hydration is very important for patients with a high body temperature. Particular drug to lower a patient's body heat.