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INNOKuhsDMS Presentation InCosmetics Asia Short Summary PDF
INNOKuhsDMS Presentation InCosmetics Asia Short Summary PDF
A Agenda d
The lipid p barrier intercellular lipids p Disruptive effects on the lipid barrier and their manifestations DMS - delivering to the skin what it needs DMS - efficacy studies and handling aspects Summary
Physiological structure
lamellar arrangement of water and oil phase
Target
High tolerance by all skin types Product safety combined with highest possible efficacy Targeted delivery of actives (where desired)
Comparison C i of f Composition C ii
skin lipids
triglycerids squalen ceramides cholesterol phospholipids
DMS cream
caprylic/capric triglycerids squalane ceramide 3 phytosterols p y phospholipids (plant.) (plant ) (plant.) (yeast) (plant.) (p ) (plant.)
Structures Compared
DMS Cream
(Freeze fracture EM)
O/W cream
(1000 x LM)
Stratum Corneum
(Freeze fracture EM)
Claim Substantiation
Prolonged Moisturization Clinical effect in AD (Physiogel AI ATOPA) Barrier enhancement
Protection against hydro hydro-& lipophilic irritants Comparative barrier integrity study DMS vs. conventional emulsifier
DMS / lipid ratio > 10% DMS 1:1 app. > 20% DMS 1:1 1:1,5 app. No further surfactants / emulsifiers in the final formula Electrolytes may have an impact on the DMS stability, stability max. 5% recommended