17-10-2014

17
th
October, 2014 Volume No.: 38 Issue No.: 02
Vision
TO REACH THE PINNACLE OF GLORY AS A CENTRE OF EXCELLENCE IN THE FIELD
OF PHARMACEUTICAL AND BIOLOGICAL SCIENCES BY KNOWLEDGE BASED
LEARNING AND PRACTICE
Contents
Message from PRINCIPAL
Editorial board
Historical article
News Update
Knowledge based Article
Disease Related Breaking
News
Upcoming Events
Drugs Update
Campus News
Students Section
Editors Note
Archive
GNIPST Photo Gallery
For your comments/contribution
OR For Back-Issues,
mailto:gnipstbulletin@gmail.com
GURU NANAK INSTITUTE OF PHARMACEUTICAL
SCIENCE AND TECHNOLOGY

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MESSAGE FROM PRINCIPAL

"It can happen. It does happen.
But it can't happen if you quit." Lauren Dane.
We are what we repeatedly do.
Excellence then is not an act, but a habit. Aristotle
It gives me immense pleasure to pen a few words for our e-bulletin. At the onset I would like to thank the
last years editors and congratulate the newly selected editors for the current year.
Our first consideration is always in the best interest of the students. Our goal is to promote academic
excellence and continuous improvement.
I believe that excellence in education is aided by creating a learning environment in which all learners are
supported in maximizing their potential and talents. Education needs to focus on personalized learning
and instruction, while promoting an education system that is impartial, universally accessible, and meeting
the needs of all students.
It is of paramount importance that our learners have sufficient motivation and encouragement in order to
achieve their aims. We are all very proud of you, our students, and your accomplishments and look
forward to watching as you put your mark on the profession in the years ahead.
The call of the time is to progress, not merely to move ahead. Our progressive Management is looking
forward and wants our Institute to flourish as a Post Graduate Institute of Excellence. Steps are taken in
this direction and fruits of these efforts will be received by our students in the near future. Our Teachers
are committed and dedicated for the development of the institution by imparting their knowledge and play
the role of facilitator as well as role model to our students.
The Pharmacy profession is thriving with a multitude of possibilities, opportunities and positive
challenges. At Guru Nanak Institute of Pharmaceutical Science and Technology, our focus is on holistic
needs of our students.
I am confident that the students of GNIPST will recognize all the possibilities, take full advantage of the
opportunities and meet the challenges with purpose and determination.
Excellence in Education is not a final destination, it is a continuous walk. I welcome you to join us on
this path.
My best wishes to all.
Dr. A. Sengupta
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EDITORIAL BOARD
CHIEF EDITOR DR. ABHIJIT SENGUPTA
EDITOR MS. JEENATARA BEGUM
ASSOCIATE EDITOR MR. DIPANJAN MANDAL
HISTORICAL ARTICLE
The First Apothecary Shops:
The Arabs separated the arts of apothecary and physician,
establishing in Bagdad late in the eighth century the first privately
owned drug stores. They preserved much of the Greco-Roman
wisdom, added to it, developing with the aid of their natural
resources syrups, confections, conserves, distilled waters and
alcoholic liquids. The apothecary is examining logs of sandalwood
offered by a traveling merchant, while children indulge their taste
for sweets with stalks of sugar cane. When the Moslems swept
across Africa, Spain and southern France, they carried with them a
new pattern of Pharmacy which western Europe soon assimilated.
NEWS UPDATE
16
th
October World Food Day:
World Food Day is celebrated every year around the world on 16
October in honor of the date of the founding of the Food and
Agriculture Organization of theUnited Nations in 1945. The day is
celebrated widely by many other organisations concerned with
food security, including the World Food Programme and
theInternational Fund for Agricultural Development.
The World Food Day theme for 2014 is Family Farming: Feeding
the world, caring for the earth
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High-speed evolution in the lab: Geneticists
evaluate cost-effective genome analysis: (17
th

October, 2014)
Life implies change. And this holds true for genes as well.
Organisms require a flexible genome in order to adapt to changes
in the local environment. Researchers want to know why
individuals differ from each other and how these differences are
encoded in the DNA. In two review papers, they discuss why DNA
sequencing of entire groups can be an efficient and cost-effective
way to answer these questions.
Scientific breakthrough will help design
antibiotics of the future: (17
th
October, 2014)
Computer simulations have been used to show how bacteria are
able to destroy antibiotics -- a breakthrough which will help
develop drugs which can effectively tackle infections in the future.
Improving bladder function among people with
spinal cord injuries: (17
th
October, 2014)
New research may lead to dramatically fewer bladder infections
following spinal cord injuries and other traumatic injuries --
infections that can cause kidney damage, and even death, scientists
report.
Physicists sound warning to 'nail beauty
fanatics': (17
th
October, 2014)
The daily trimming of fingernails and toenails to make them more
aesthetically pleasing could be detrimental and potentially lead to
serious nail conditions.
Cystic Fibrosis lung infection: Scientists open
black box on bacterial growth: (17
th
October,
2014)
Researchers have shown for the first time how bacteria can grow
directly in the lungs of Cystic fibrosis patients, giving them the
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opportunity to get tremendous insights into bacteria behavior and
growth in chronic infections.
Divide and conquer: Novel trick helps rare
pathogen infect healthy people: (17
th
October,
2014)
New research into a rare pathogen has shown how a unique
evolutionary trait allows it to infect even the healthiest of hosts
through a smart solution to the body's immune response against it,
scientists report.
Emergency aid for overdoses: (17
th
October,
2014)
Every minute counts in the event of an overdose. Now, researchers
have developed an agent to filter out toxins from the body more
quickly and efficiently. It can also be used for dialysis in patients
suffering from hepatic failure.
Presence of enzyme may worsen effects of
spinal cord injury and impair long-term recovery:
(17
th
October, 2014)
Traumatic spinal cord injury (SCI) is a devastating condition with
few treatment options. Studies show that damage to the barrier
separating blood from the spinal cord can contribute to the
neurologic deficits that arise secondary to the initial trauma.
Through a series of experiments, researchers suggest that matrix
metalloproteinase-3 (MMP-3) plays a pivotal role in disruption of
the brain/spinal cord barrier (BSCB), cell death, and functional
deficits after SCI. This link also presents new therapeutic
possibilities.
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First step: From human cells to tissue-
engineered esophagus: (17
th
October, 2014)
In a first step toward future human therapies, researchers have
shown that esophageal tissue can be grown in vivo from both
human and mouse cells.
Cellular self-destruct program has deep roots
throughout evolution: (16
th
October, 2014)
In what seems like a counter-intuitive move against survival,
within animals, some cells are fated to die from the triggering of an
elaborate cell death program, known as apoptosis. Now,
researchers have honed in on understanding the evolution of
caspase-8, a key cell death initiator molecule that was first
identified in humans.
For detail mail to editor
KNOWLEDGE BASED ARTICLE
Hyperuricemia (High Uric Acid)
Hyperuricemia is an excess of uric acid in the blood. Uric acid passes
through the liver, and enters your bloodstream. Most of it is excreted
(removed from your body) in your urine, or passes through your
intestines to regulate "normal" levels.
Normal Uric acid levels are 2.4-6.0 mg/dL (female) and 3.4-7.0 mg/dL
(male). Normal values will vary from laboratory to laboratory.
Also important to blood uric acid levels are purines. Purines are
nitrogen-containing compounds, which are made inside the cells of
your body (endogenous), or come from outside of your body, from
foods containing purine (exogenous). Purine breaks down into uric
acid. Increased levels of uric acid from excess purines may
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accumulate in your tissues, and form crystals. This may cause high
uric acid levels in the blood.
Uric acid formation may occur when the blood uric acid level rises
above 7 mg/dL. Problems, such as kidney stones, and gout (collection
of uric acid crystals in the joints, especially in your toes and fingers),
may occur.
Causes:
Causes of high uric acid levels (hyperuricemia) can be primary
(increased uric acid levels due to purine), and secondary (high uric
acid levels due to another disease or condition). Sometimes, the body
produces more uric acid than it is able to excrete.
Causes of high uric acid levels include:
Primary hyperuricemia
Increased production of uric acid from purine
Your kidneys cannot get rid of the uric acid in your blood, resulting
in high levels
Secondary hyperuricemia
Certain cancers, or chemotherapy agents may cause an increased
turnover rate of cell death. This is usually due to chemotherapy, but
high uric acid levels can occur before chemotherapy is administered.
After chemotherapy, there is often a rapid amount of cellular
destruction, and tumor lysis syndrome may occur. You may be at risk
for tumor lysis syndrome if you receive chemotherapy for certain
types of leukemia, lymphoma, or multiple myeloma, if there is a large
amount of disease present.
Kidney disease - this may cause you to not be able to clear the uric
acid out of your system, thus causing hyperuricemia.
Medications - can cause increased levels of uric acid in the blood
Endocrine or metabolic conditions -certain forms of diabetes, or
acidosis can cause hyperuricemia
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Elevated uric acid levels may produce kidney problems, or none at
all. People may live many years with elevated uric acid levels, and
they do not develop gout or gouty arthritis (arthritis means "joint
inflammation"). Only about 20% of people with elevated uric acid
levels ever develop gout, and some people with gout do not have
significantly elevated uric acid levels in their blood.
Symptoms:
People may not have any symptoms.
If patients blood uric acid levels are significantly elevated, and
undergoing chemotherapy for leukemia or lymphoma, patient may
have symptoms kidney problems, or gouty arthritis from high uric
acid levels in your blood.
Patient may have fever, chills, fatigue if you have certain forms of
cancer, and your uric acid levels are elevated (caused by tumor lysis
syndrome)
Inflammation of a joint (called "gout") can occour, if the uric acid
crystals deposit in one of the joints. (*Note- gout may occur with
normal uric acid levels, too).
Patient may have kidney problems (caused by formation of kidney
stones), or problems with urination
Foods that are high in purine include:
All organ meats (such as liver), meat extracts and gravy
Yeasts, and yeast extracts (such as beer, and alcoholic beverages)
Asparagus, spinach, beans, peas, lentils, oatmeal, cauliflower and
mushrooms
Foods that are low in purine include:
Refined cereals - breads, pasta, flour, tapioca, cakes
Milk and milk products, eggs
Lettuce, tomatoes, green vegetables
Cream soups without meat stock
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Water, fruit juice, carbonated drinks
Peanut butter, fruits and nuts
Keep well hydrated, drinking 2 to 3 liters of water per day, unless
you were told otherwise.
Take all of your medications for hyperuricemia as directed
Avoid caffeine and alcohol, as these can contribute to problems with
uric acid and hyperuricemia.
Avoid medications, such as thiazide diuretics (hydrochlortiazide),
and loop diuretics (such as furosemide or Lasix

). Also, drugs such as

niacin, and low doses of aspirin (less than 3 grams per day) can
aggravate uric acid levels. Do not take these medications, or aspirin
unless a healthcare provider who knows your condition told you.
If you experience symptoms or side effects, especially if severe, be
sure to discuss them with your health care team. They can prescribe
medications and/or offer other suggestions that are effective in
managing such problems.
Treatment:
Non-steroidal anti-inflammatory (NSAID) agents and Tylenol

- such
as naproxen sodium and ibuprofen may provide relief of gout-related
pain. Gout may be a result of a high uric acid level.
If to avoid NSAID drugs, because of the type of cancer or
chemotherapy you are receiving, acetaminophen (Tylenol() up to
4000 mg per day (two extra-strength tablets every 6 hours) may
help.
It is important not to exceed the recommended daily dose of Tylenol,
as it may cause liver damage.
Uricosuric Drugs: These drugs work by blocking the reabsorption of
urate, which can prevent uric acid crystals from being deposited into
the tissues. Examples of uricosuric drugs include probenecid, and
sulfinpyrazone.
Xanthine oxidase inhibitors - Such as allopurinol, will prevent gout.
However, it may cause the symptoms of gout to be worse if it is
taken during an episode of painful joint inflammation.
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Allopurinol may also be given to the patients, if they have a certain
form of leukemia or lymphoma, to prevent complications from
chemotherapy and tumor lysis syndrome - and not necessarily to
prevent gout. With high levels of uric acid in your blood, as a result
of the disease, the uric acid will collect and form crystals in the
kidneys. This may occur during chemotherapy, and may cause
kidneys to fail.
Jeenatara Begum
Assistant Professor
GNIPST
DISEASE RELATED BREAKING NEWS
Middle East respiratory syndrome coronavirus
(MERS-CoV) Saudi Arabia: (16
th
October,
2014)
The National IHR Focal Point of Saudi Arabia (SAU) has reported
additional laboratory-confirmed cases of infection with Middle
East respiratory syndrome coronavirus (MERS-CoV) to WHO.
Read more
UPCOMING EVENTS
5
th
International Conference on Stem Cells and Cancer 2014, JNU
Convention Centre, New Delhi, India from 8-10 November, 2014
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DRUGS UPDATES
FDA Approves Esbriet (pirfenidone) for
Idiopathic Pulmonary Fibrosis: (15
th
October,
2014)
The U.S. Food and Drug Administration today approved Esbriet
(pirfenidone) for the treatment of idiopathic pulmonary fibrosis
(IPF). Read more
CAMPUS NEWS
The Cultural Programme on Bijoya Dashami and Kali Puja will be
held on 20
th
October, 2014
An exhibition on Photography and Painting will be held on 20
th

October, 2014
The GNIPST Cricket Tournament will be held on 21
st
and 22
nd

October, 2014.
Congratulation to the winner of Football Tournament-B.Pharm
3rd year, 2014
Runner up team-B.Pharm final year, 2014
Congratulation to the winner of Table Tennis Tournament-
Krishnakali Basu, B.Pharm 3rd year, 2014
1st Runner up-Aindrila Bhowmick, B.Pharm 2nd year, 2014
2nd Runner up-Sayani Banerjee, B.Pharm 2nd year, 2014
The GNIPST Football Tournament (for male students) and Table
Tennis tournament (for female students) was held on 25th and
26th September, 2014.
On 5
th
September, 2014 the students of GNIPST have arranged a
wonderful Teachers Day Programme. On behalf of all the teachers
of GNIPST I would like to thank our beloved students.
The Freshers welcome programme was held on 14
th
August, 2014.
Welcome 1
st
year students.
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We congratulate the following M.Pharm. final year students who
have made their positions in different pharmaceutical companies.
Anirban Banerjee (Emami Ltd.)
Mahender Roy (Stadmed private Ltd.)
We congratulate the following B.Pharm. final year students for
their success.
Samadrita Mukherjee (Abbott India Ltd.)
Suman Sarkar (Tata Medical Centre-Apollo Pharmacy)
Shrewashee Mukherjee (Fresenius Kabi-Parenteral Nutrition)
Avishek Naskar (Glaxo SmithKline-Marketing)
Bappaditya Manik (USV Limited)
Sarbani Das (Nutri Synapzz-Marketing)
Ankita Roy (Nutri Synapzz-Marketing)
Rahul Mitra (B M Pharmaceuticals-Production)
The following B.Pharm. final year students have qualified, GPAT-
2014. We congratulate them all.
Utsha Sinha
Satarupa Bhattacharya
Sandipan Sarkar
Purbali Chakraborty
Reminiscence, 2014(GNIPST Reunion) was held in College
campus on 2
nd
February,2014.
1
st
Annual Sports of GNIPST was held on 3
rd
February,2014 in
College campus ground.
An industrial tour and biodiversity tour was conducted in Sikkim
for B.Pharm and B.Sc. students under the supervision of Mr. Asis
Bala, Ms. Jeentara Begum and Ms. Moumita Chowdhury.
B.Pharm 3
rd
year won the GNIPST Football Champions trophy,
2013. B.Pharm 3
rd
year won the final match 1-0 against B.Pharm 2
nd

year. Deep Chakraborty was the only scorer of the final.
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STUDENTS SECTION
WHO CAN ANSWER FIRST????
Literally meaning of which asian city
is kind river?
What was the name of 1st asian games
mascot?
Answer of Previous Issues Questions:
A) White Tiger
B) ISRO
Congratulation Aindrila Bhowmick for your correct answer
Identify the lady
Answer of Previous Issues Image:
Arvind Adiga
Send your thoughts/
Quiz/Puzzles/games/write-ups or any other
contributions for Students Section&
answers of this Section at gnipstbulletin@gmail.com
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EDITORS NOTE
It is a great pleasure for me to publish the 2
nd
issue of 38
th
Volume
of GNIPST BULLETIN. All the followers of GNIPST BULLETIN
are able to avail the bulletin through facebook account GNIPST
bulletin I am very much thankful to all the GNIPST members and
readers who are giving their valuable comments, encouragements
and supports. I am also thankful to Dr. Abhijit Sengupta, Director
of GNIPST for his valuable advice and encouragement. Special
thanks to Dr. Prerona Saha, Mr. Debabrata Ghosh Dastidar
and Mr. Soumya Bhattacharya for their kind co-operation and
technical supports. Thank you Mr. Soumya Bhattacharya for the
questionnaires of the student section. An important part of the
improvement of the bulletin is the contribution of the readers. You
are invited to send in your write ups, notes, critiques or any kind of
contribution for the forthcoming special and regular issue.
I wish all the GNIPST members and readers a very Happy Puja.

ARCHIVE
Students of GNIPST organized pre puja celebration programme,
Saaranya on 7
th
October, 2013 in college Auditorium.
GNIPST organized a garment distribution programme on 28
th

September, 2013 at Dakshineswar Kali Temple and Adyapith,
Kolkata. On this remarkable event about hundred people have
received garments. More than hundred students and most of the
faculties participated on that day with lot of enthusiasm.
GNIPST celebrated World Heart Day (29
th
September) and
Pharmacists Day (25
th
September) on 25
th
and 26
th
September,
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2013 in GNIPST Auditorium. A seminar on Violence against
woman and female foeticide was held on GNIPST Auditorium on
25
th
September organized by JABALA Action Research
Organization. On 26
th
September an intra-college Oral and Poster
presentation competition related to World Pharmacists day and
Heart day was held in GNIPST. Ms. Purbali Chakraborty of
B.Pharm 4
th
year won the first prize in Oral Presentation. The
winner of Poster presentation was the group of Ms. Utsa Sinha,
Mr. Koushik Saha and Mr. Niladri Banerjee (B.Pharm 4
th
year). A
good number of students have participated in both the
competition with their valuable views.
Teachers day was celebrated on 5
th
September, 2013 by the
students of GNIPST in GNIPST Auditorium.
Azalea (exotic flower ) , the fresher welcome programme for
newcomers of GNIPST in the session 2013-14 was held on 8
th

August in GNIPST Auditorium.
One day seminar cum teachers development programme for
school teachers on the theme of Recent Trends of Life Sciences
in Higher Education organized by GNIPST held on 29
th
June,
2013 at GNIPST auditorium. The programme was inaugurated by
Prof . Asit Guha, Director of JIS Group, Mr. U.S. Mukherjee, Dy
Director of JIS Group and Dr. Abhijit Sengupta, Director cum
Principal of GNIPST with lamp lighting. The programme started
with an opening song performed by the B.Pharm students of this
institute. The seminar consists of a series of lectures, video
presentations and poster session. On the pre lunch session 4
lectures were given by Dr. Lopamudra Dutta, Mr. Debabrata
Ghosh Dastidar, Ms. Swati Nandy and Ms. Tamalika Chakraborty
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respectively. On their presentation the speakers enlighten the
recent development of Pharmacy, Genetics and Microbiology and
their correlation with Life Sciences. On the post lunch session, Ms.
Saini Setua and Ms. Sanchari Bhattacharjee explained the recent
development and career opportunities in Biotechnology and
Hospital Management. The programme was concluded with
valedictory session and certificate distribution.
About 50 Higher secondary school teachers from different
schools of Kolkata and North& South 24 Parganas district of West
Bengal participated in this programme. A good interactive session
between participants and speakers was observed in the seminar.
The seminar was a great success with the effort of faculties, staffs
and students of our Institute. It was a unique discussion platform
for school teachers and professional of the emerging and newer
branches of Life Science.
The general body meeting of APTI, Bengal Branch has been
conducted at GNIPST on 15
th
June, 2012. The program started with
a nice presentation by Dr. Pulok Kr. Mukherjee, School of Natural
Products, JU on the skill to write a good manuscript for
publication in impact journals. It was followed by nearly two hour
long discussion among more than thirty participants on different
aspects of pharmacy education. Five nonmember participants
applied for membership on that very day.
GNIPST is now approved by AICTE and affiliated to WBUT for
conducting the two years post graduate course (M.Pharm)
in PHARMACOLOGY. The approved number of seat is 18.
The number of seats in B.Pharm. has been increased from 60 to
120.
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AICTE has sanctioned a release of grant under Research
Promotion Scheme (RPS) during the financial year 2012-13to
GNIPST as per the details below:
a. Beneficiary Institution: Guru Nanak Institution of Pharmaceutical
Science & Technology.
b. Principal Investigator: Dr. LopamudraDutta.
c. Grant-in-aid sanctioned:Rs. 16,25000/- only
d. Approved duration: 3 years
e. Title of the project: Screening and identification of potential
medicinal plant of Purulia & Bankura districts of West Bengal
with respect to diseases such as diabetes, rheumatism, Jaundice,
hypertension and developing biotechnological tools for enhancing
bioactive molecules in these plants.
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