In previous presevations, we gave been introduced about acnes and negative effect of acnes, but you

shoudnt be worry because there are many ways can treat or control them. The key is working with your
dematologist to find out whats best for you.
Our presevation discuss three main therapy:
- Topical therapy
- Systemic therapy
- Physical therapy
I am going to talk about topical and systemic therapy, the last therapy will be introduced by the next partner.
Topical therapy => this therapy is useful in mild and moderate acnes
In topical agents, drugs or gel contain bezoyl peroxide, antibiotics, retinoids, etc are the mainstay of
treatment. They can be given in conbination and the result is the numbers of inflamed lesion are reduced. Specially,
topical antibiotics are mainly used for fighting against Propionibacterium acnes.
Systemic therapy => this treatment is a mainstay to treat moderate-to-severe inflamed acne vulgaris
Systemic therapy includes oral antibiotics and hormonal therapy. Depending upon the need of patient, it has
to be selected.
+ oral antibiotics have anti-inflamed influence and they also have ability to kill Propionibacterium acnes.
+ hormonal therapy in acne is to prevent the effects of androgens on the sebaceous gland and probably
follicular keratinocyctes as well
So, Ive explained two of three main methods. I would welcome any suggestions. To be contined, physical therapy
will be discussed by

Acne treatment[edit]
Benzoyl peroxide works as a peeling agent. It increases skin turnover, clearing pores and reducing the
bacterial count (specifically P. acnes) as well as acting directly as an antimicrobial. [3] It may be combined
with salicylic acid, sulfur, erythromycin or clindamycin(antibiotics), and adapalene (a synthetic retinoid). Two
common combination drugs include benzoyl peroxide/clindamycin andadapalene/benzoyl peroxide, a unique
formulation considering most retinoids are deactivated by peroxides.
Benzoyl peroxide for acne treatment is typically applied to the affected areas in gel or cream form, in
concentrations of 2.5% increasing through 5%, and up to 10%. Research suggests that 5% and 10%
concentrations are slightly more effective than 2.5%, while 2.5% is usually better tolerated than the 10%
concentration, though the majority of major studies comparing it to other treatments use the higher
concentrations.[4][5]
Benzoyl peroxide commonly causes initial dryness and sometimes irritation, although
the skin develops tolerance after a week or so. A small percentage of people are much more sensitive to it
and liable to suffer burning, itching, peeling and possiblyswelling.[citation needed] It is sensible to apply the lowest

concentration and build up as appropriate. Once tolerance is achieved, increasing the quantity or
concentration and gaining tolerance at a higher level may give better subsequent acne clearance. [citation needed]