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B9 - The Role of Dual Energy Imaging in The Detection of Pulmonary Lung Nodules, Aislinn Adair PDF
B9 - The Role of Dual Energy Imaging in The Detection of Pulmonary Lung Nodules, Aislinn Adair PDF
Background
Lung cancer
35,000 deaths each year1
39,000 new cases of lung cancer diagnosed in the UK every year2
Survival rates3: 1 year <35%, 5 years 7.8-9.3%, 10 years 4.9-5.9%
Background
Chest X-ray missed diagnosis
Aim
Methodology
Systematic Literature Review
Results
Radiation Dose
CXR - 0.02mSv8
Dual energy imaging - 0.04mSv8 (max.)
CT - 6.6mSv8
Diagnostic Accuracy
ROC analysis
All studies reported statistically significant differences in detection rates
for pulmonary nodules using dual energy imaging9,I0,11,
Image Quality
Dual energy imaging: superior image quality (than CXR)9,10,11,12
Results
Improved detection rates
Improves accuracy of detection rates of pulmonary nodules9,10,11,12,13
Sensitivity
CXR9
33.5 - 52.5%
43.5 - 58.5%
Conclusion
the use of dual energy chest imaging could offer the potential of a
higher sensitivity for the detection of pulmonary nodules, compared to
standard CXR.
References &
Acknowledgements
1 - http://www.nhs.uk/Livewell/Lungcancer/Pages/Lungcancermythsandfacts.aspx [Last accessed 12th Feb 2013]
2 - UK Lung Cancer coalition (2012) Patient Information Available from: http://www.uklcc.org.uk/ [Last accessed on 31st May
2013]
3 - http://www.cancerresearchuk.org/cancer-info/cancerstats/types/lung/survival/lung-cancer-survival-statistics [Last accessed
on 31st May 2013]
4 - NICE Guidelines. (2012). Patient Pathways. [online] Available from:
http://www.nice.org.uk/Search.do?x=0&y=0&searchText=patient+pathway+lung+cancer&newsearch=true#/search/?reload.[Las
t accessed 23rd Feb 2013]
5 - Austin, J., Miyagawa, M., Yasuhara, Y., Murakami, T., Ikura, H., Sakamoto, K., Tagashira, H., Arakawa, K., Mochizuki, T.,
(1992) Clinical Evaluation of Pulmonary Nodules with Dual-exposure Dual-energy Subtraction Chest Radiography. Radiation
Medicine 23 (6) pp. 391 397
6 - Sackett, D., Rosenberg, W., Muir-Gray, J., Haynes, R., Richardson, W (1996) Evidence Based Medicine. What is it and
what it isnt British Medical Journal 312: pp. 71 72
7 - Williman, A. and Appleton, S., (2009) Critical appraisal strategies. Sage Publications Limited : London.
8 - Health Protection Agency (2012) Radiation Protection [Online] Available from: http://www.hpa.org.uk/ [Last accessed 12 th
Jan 2013]
9 - Szucs-Farkas, Z., Yuksel-Hatz, A., Patak, M. A., Ruder., Single-exposure dual-energy subtraction chest
radiography: Detection of pulmonary nodules and masses in clinical practice University Hospital of Berne