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Carum Carvi Monograph
Carum Carvi Monograph
Carum Carvi Monograph
Umbelliferae
or
Apiaceae
Native
to
Europe,
North
Africa,
and
Asia
Part
used
is
fruit
(though
leaves
have
similar
properties)
History
Long
history,
mentioned
by
Pliny
Dioscorides
recommended
the
oil
for
pale
faced
girls
Popular
in
the
middle
ages,
mentioned
in
Shakespeares
Henry
IV
Widely
used
as
a
Glavouring
in
Europe
and
Asia
Tradition
had
it
that
they
gave
the
gift
of
retention
(vs
theft
and
Gickle
love)
Cultivation
28%
cultivated
in
Finland
as
well
suited
to
the
Finnish
climate
and
latitudes
which
ensure
long
hours
of
sunlight
in
the
summer.
Like
many
umbellifers,
is
a
useful
companion
plant.
It
can
hide
the
scent
of
neighbouring
crops
from
pest
insects,
as
well
as
attracting
beneGicial
insects
to
its
Glowers.
Composition
The
fruits,
have
a
pungent,
aniseed
Glavor
and
aroma
i.
Volatile
oil,
consisting
of
carvone
(40-60%),
and
limonene,
with
dihydrocarvone,
carveol,
dihydrocarveol,pinene,
thujone,
anethofuran.
ii.
A
series
of
p-menthane
trials
and
their
glucosides
iii.
Flavonoids,
mainly
quercetin
derivatives
Usage
Widely
used
in
Ayurveda
and
Unani.
Less
so
in
Western
Herbal
Medicine,
no
one
seems
to
sell
tincture,
just
seeds
or
essential
oil.
Long
tradition
of
medical
uses,
primarily
for
stomach
complaints.
Often
used
for
Wind
and
Colic
in
Children,
loss
of
appetite,
Glatulant
indigestion,
diarrhoea
in
children,
colds,
period
pains,
stimulate
Glow
of
breast
milk
Antimicrobial
Antispasmodic
Carminative
Expectorant
Galactagogue
Emmenagogue
Dosage
Tea
1
teaspoon
to
half
a
cup
of
boiling
water
3
times
a
day
Tincture
1:5
45%
10ml
-
70ml
(BNF)
Research
Antioxidant
-
particularly
the
oil
in
vivo
(polyphenols)
Antimicrobial
-
particularly
carvacrol
in
vivo
Anti
carcinogenic
-
dietary
supplements
prevent
colon
cancer
in
rats
Anti
diabetic
-
Anti-hyperglcemic
action
in
diabetic
rats
Diuretic
-
Shown
to
be
effective
on
rats
Oestrogenic
-
In
rats
showed
to
modulate
FSH
and
LH
Gastrointestinal
-
Human
trials
showed
success
in
receiving
dyspepsia,
thought
to
be
by
inhibitory
affect
on
smooth
muscle
in
GIT.
In
vivo
showed
effect
against
helicobacter
pylori.
Cholesterol
and
tryglyceride
lowering
-
lowers
both
in
rats
Bioenhancer
for
tuberculosis
medicines
-
Shown
to
enhance
combination
of
rifampicin,
isoniazid,
and
pyrazinamide
used
in
tuberculosis
treatment
References
BARTRAM,
T.
(1995)
Encyclopedia
of
herbal
medicine.
Christchurch:
Grace.
GRIEVE,
M.
&
LEYEL,
C.
F.
M.
(1998)
A
modern
herbal:
the
medicinal,
culinary,
cosmetic
and
economic
properties,
cultivation
and
folklore
of
herbs,
grasses,
fungi,
shrubs
and
trees
with
all
their
modern
scienti=ic
uses.
London:
Tiger.
JOHRI,
R.
K.
(2011)
Cuminum
cyminum
and
Carum
carvi:
An
update.
Pharmacognosy
reviews,
Vol
5,
No
9,
pp.
63-72.
KAMALEESWARI,
M.,
DEEPTHA,
K.,
SENGOTTUVELAN,
M.
&
NALINI,
N.
(2006)
Effect
of
dietary
caraway
(
Carum
carvi
L.)
on
aberrant
crypt
foci
development,
fecal
steroids,
and
intestinal
alkaline
phosphatase
activities
in
1,2-dimethylhydrazine-induced
colon
carcinogenesis.
Toxicology
and
applied
pharmacology,
Vol
214,
No
3,
pp.
290-296.
KESHAVARZ,
A.,
MINAIYAN,
M.,
GHANNADI,
A.
&
MAHZOUNI,
P.
(2013)
Effects
of
Carum
carvi
L.
(Caraway)
extract
and
essential
oil
on
TNBS-induced
colitis
in
rats.
Research
in
pharmaceutical
sciences,
Vol
8,
No
1,
pp.
1.
LEMHADRI,
A.,
HAJJI,
L.,
MICHEL,
J.
B.
&
EDDOUKS,
M.
(2006)
Cholesterol
and
triglycerides
lowering
activities
of
caraway
fruits
in
normal
and
streptozotocin
diabetic
rats.
Journal
of
ethnopharmacology,
Vol
106,
No
3,
pp.
321-326.
RAZZAGHI-ABYANEH,
M.,
SHAMS-GHAHFAROKHI,
M.,
REZAEE,
M.-B.,
JAIMAND,
K.,
ALINEZHAD,
S.,
SABERI,
R.
&
YOSHINARI,
T.
(2009)
Chemical
composition
and
antiaGlatoxigenic
activity
of
Carum
carvi
L.,
Thymus
vulgaris
and
Citrus
aurantifolia
essential
oils.
Food
Control,
Vol
20,
No
11,
pp.
1018-1024.
SAMOJLIK,
I.,
MIMICA-DUKI,
N.,
LAKIC,
N.,
NIKOLIC,
A.,
BOGAVAC,
M.
&
BOZIN,
B.
(2008)
Antioxidant
activities
of
Carum
carvi
L.
and
Coriandrum
sativum
L.,
Apiaceae
essential
oils.
Planta
Medica,
Vol
74,
No
9,
pp.
PI26.
SUSHRUTA,
K.,
SPANDANA,
R.
K.
&
SATYANARAYANA,
S.
(2009)
Adaptogenic
and
nootropic
activities
of
aqueous
extract
of
Carum
carvi
Linn.
(Caraway)
fruit:
An
experimental
study
in
Wistar
rats.
Planta
Medica,
Vol
75,
No
9,
pp.
PC9.
WEISS,
R.
F.
(1988)
Herbal
medicine.
BeaconsGield;
Gothenburg:
A.
B.
Arcanum.
WILLIAMSON,
E.
M.
&
WREN,
R.
C.
(2003)
Potter's
herbal
cyclopedia:
the
authoritative
reference
work
on
plants
with
a
known
medical
use.
Saffron
Walden:
C.W.
Daniel.