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Quantum Consciousness
Quantum Consciousness
What is Consciousness?
Table of Contents
1. The problem of consciousness
2. Microtubules
3. Pan-experiential philosophy
meets modern physics
4. Quantum computing and
consciousness
5. Roger Penrose's 'objective
reduction'
6. Are proteins qubits?
7. Microtubule quantum automata
- the 'Orch OR' model
8. Orch OR, cognition and free will
9. Consciousness and evolution
10. Conclusions
11. Acknowledgements/References
Figure 1. PET scan image of brain showing visual and auditory recognition (from S Petersen, Neuroimaging
Laboratory, Washington University, St. Louis. Also see J.A. Hobson "Consciousness," Scientific American
Library, 1999, p. 65).
fitting the brain to a computational view, such explanations omit incompatible neurophysiological details:
Widespread apparent randomness at all levels of neural processes (is it really noise, or underlying levels
of complexity?);
Glial cells (which account for some 80% of brain);
Dendritic-dendritic processing;
Electrotonic gap junctions;
Cytoplasmic/cytoskeletal activities; and,
Living state (the brain is alive!)
A further difficulty is the absence of testable hypotheses in emergence theory. No threshold or rationale is
specified; rather, consciousness "just happens".
Finally, the complexity of individual neurons and synapses is not accounted for in such arguments. Since many
forms of motile single-celled organisms lacking neurons or synapses are able to swim, find food, learn, and
multiply through the use of their internal cytoskeleton, can they be considered more advanced than neurons?
Figure 3. Single cell paramecium can swim and avoid obstacles using its cytoskeleton.
Are neurons merely simple switches?
2. Microtubules
Activities within cells ranging from single-celled organisms to the brain's neurons are organized by a dynamic
scaffolding called the cytoskeleton, whose major components are microtubules. Hollow, crystalline cylinders 25
nanometers in diameter, microtubules are comprised of hexagonal lattices of proteins, known as tubulin.
Microtubules are essential to cell shape, function, movement, and division. In neurons microtubules
self-assemble to extend axons and dendrites and form synaptic connections, then help to maintain and
regulate synaptic activity responsible for learning and cognitive functions. Microtubules interact with
membrane structures mechanically by linking proteins, chemically by ions and "second-messenger" signals,
and electrically by voltage fields.
Figure 4. Schematic view of two neurons connected by chemical synapse. Axon terminal (above) releases
neurotransmitter vesicles which bind receptors on post-synaptic dendritic spine. Within neurons are visible
cytoskeletal structures microtubules ("MTs" - thicker tubes) as well as actin, synapsin and others which
connect MTs to membranes. Also, MT-associated proteins ("MAPs") interconnect MTs.
Figure 5. Immunoelectron micrograph of dendritic microtubules interconnected by MAPs. Some MTs have
been sheared, revealing internal hollow core. The granular "corn-cob" surface of MTs is barely evident to close
inspection. Scale bar, lower left: 100 nanometers. With permission from Hirokawa, 1991.
Figure 7. Left: Microtubule (MT) structure: a hollow tube of 25 nanometers diameter, consisting of 13 columns
of tubulin dimers arranged in a skewed hexagonal lattice (Penrose, 1994). Right (top): Each tubulin molecule
may switch between two (or more) conformations, coupled to London forces in a hydrophobic pocket. Right
(bottom): Each tubulin can also exist (it is proposed) in quantum superposition of both conformational states.
Figure 8. Microtubule automaton simulation (from Rasmussen et al., 1990). Eight nanosecond time steps of a
segment of one microtubule are shown in "classical computing" mode in which conformational states of
tubulins are determined by dipole-dipole coupling between each tubulin and its six (asymmetrical) lattice
neighbors. Conformational states form patterns which move, evolve, interact and lead to emergence of new
patterns.
Microtubule automata switching offers a potentially vast increase in the computational capacity of the brain.
18
Conventional approaches focus on synaptic switching at the neural level which optimally yields about 10
11
11
neurons with
-1
~10 tubulins/neuron, switching at ~10 sec ). Indeed, the fact that all biological cells typically contain
7
approximately 10 tubulins could account for the adaptive behaviors of single-celled organisms which have no
nervous system or synapses. Rather than simple switches, neurons are complex computers.
Figure 9. Quantum electodynamics (QED) predicts a foam of erupting and collapsing virtual particles which
may be visualized as topographic distortions of the fabric of spacetime. Adapted from Thorne (1994) by Dave
Cantrell.
Figure 10. A: The Casimir force of the quantum vacuum zero point fluctuation energy may be measured by
placing two macroscopic surfaces separated by a tiny gap d . As some virtual photons are excluded in the gap,
1
the net "quantum foam" pressure forces the surfaces together. In Lamoreaux's (1997) experiment, d was in
1
the range of 0.6 to 6.0 microns (~1500 nanometers). B: George Hall (1996; 1997) has calculated the Casimir
force on microtubules. As the force is proportional to d , and d for microtubules is 15 nanometers, the
-4
predicted Casimir force is 10 greater on microtubules (per equivalent surface area) than that measured by
Lamoreaux. Hall calculates a range of Casimir force on microtubules (length dependent) from 0.5 to 20
atmospheres.
At the basic level, this granularity has been modeled by Roger Penrose as a dynamic web of quantum spins.
-33
These "spin networks" create an array of geometric volumes and configurations at the Planck scale (10
cm,
-43
10
Figure 11. A spin network. Introduced by Roger Penrose (1971) as a quantum mechanical description of the
geometry of space, spin networks describe spectra of discrete Planck scale volumes and configurations (with
permission, Rovelli and Smolin, 1995).
If spin networks are the fundamental level of space-time geometry, they could provide the basis for protoconscious experience. In other words, particular configurations of quantum spin geometry would convey
particular types of qualia, meaning and aesthetic values. A process at the Planck scale (e.g. quantum state
reductions) could access and select configurations of experience.
For illustration, 4 dimensional space-time geometry is often portrayed as a 2 dimensional "space-time sheet."
Figure 12. According to Einstein's general relativity, mass is equivalent to curvature in spacetime geometry.
Penrose applies this equivalence to the fundamental Planck scale. The motion of an object between two
conformational states of a protein such as tubulin (top) is equivalent to two curvatures in spacetime geometry
Figure 13. Mass superposition, e.g. a protein occupying two different conformational states simultaneously
(top) is equivalent, according to Penrose, to simultaneous spacetime curvature in opposite directions - a
separation, or bubble ("blister") in fundamental spacetime geometry.
Figure 14. Spacetime superposition/separation bubble (bottom) will reduce, or collapse to one or the other
spacetime curvatures (top).
Superposition and subsequent reduction, or collapse, to single, classical states may have profoundly important
applications in technology, as well as toward the understanding of consciousness. In the 1980s Benioff,
Feynman, Deutsch and other physicists proposed that states in a quantum system could interact (via
entanglement) and enact computation while in quantum superposition of all possible states ("quantum
computing"). Classical computing processes bits (or conformational states) as 1 or 0, quantum computations
involve the processing of superpositioned "qubits" of both 1 and 0 (and other states) simultaneously.
Figure 15. Qubits useful in quantum computation may exist in two or more ("both") states simultaneously prior
to collapse, or reduction (left), and then in single, classical ("either, or") states after reduction (right). Spin,
quantum dots and photon polarization qubits have been proposed and/or demonstrated in prototype quantum
computers, and tubulin proteins and spacetime geometry are proposed in the Orch OR model to perform as
qubits also.
Quantum theory also tells us that two or more particles, if once together, will remain somehow connected
("entangled"), even when separated by great distances. Qubits can interact by quantum entanglement, so that
quantum computing is able to achieve a nearly infinite parallel computational ability. Quantum computers, if
they can be constructed, will be able to solve imprtant problems (e.g. factoring large numbers) with efficiency
unattainable in classical computers (Shor, 1994).
Researchers have developed a "Figure of Merit" M for proposed quantum computing technologies (Modified
from Barenco, 1996 & DiVincenzo, 1995). M is related to the number of elementary operations performed per
qubit before the superposition/computation is disrupted by decoherence (or in the case of microtubules in the
Orch OR proposal, before objective reduction terminates the superposition).
Technology
(sec)
(sec)
elem
decoherence
-19
10
-13
10
-14
10
-14
10
-14
10
-7
10
-6
10
-3
10
-9
10
-9
10
Mossbauer nucleus
10
Electrons GaAs
10
Electrons Au
10
Trapped ions
10
Optical cavities
10
Electron spin
10
Electron quantum
dots
10
Nuclear spin
10
Superconductor
islands
10
Microtubule tubulins
10
M
(operations/qubit
pre-decoherence)
-10
10
-10
10
-8
10
-1
10
-5
10
-3
10
-3
10
10
10
-1
10
3
6
13
9
4
3
7
6
8
Results, or solutions in quantum computing are obtained when, after a period of quantum
superposition/computation, the qubits "collapse", or reduce to classical bit states ("collapse of the wave
function"). As quantum superposition may only occur in isolation from environment, collapse (reduction) may
be induced by breaching isolation (this is what is envisioned in technological quantum computers - making a
measurement). But what about quantum superpositions which remain isolated, for example Schrodinger's
mythical cat which is both dead and alive? This is the famous problem of collapse of the wave function, or
quantum state reduction.
E = h/T
where E is the gravitational self-energy of the superposed mass separated from itself, h is Planck's constant
divided by 2pi, and T is the coherence time until collapse occurs. Thus, the size and energy of a system in
superposition, or the degree of space-time separation, is inversely related to the time T until reduction. (E can
be calculated from the superposed mass m and the separation distance a. See e.g. Hameroff and Penrose,
1996a.)
Assuming isolation, the following masses in superposition would collapse at the designated times, according to
Penrose's objective reduction:
Mass (m)
Time (T)
Nucleon
10 years
Beryllium ion
10 years
7
6
Water Speck
-5
cm radius
Hours
-4
cm radius
1/20 second
-3
cm radius
10
10
10
10
-3
seconds
-37
10
seconds
If quantum computation with objective reduction were occurring in the brain, enigmatic features of
consciousness (see Section above - The Problem of Consciousness) could be explained:
By occurring as a self-organizing process in what is suggested to be a pan-experiential medium of
fundamental spacetime geometry, objective reductions could account for the nature of subjective
experience by accessing and selecting proto-conscious qualia.
By virtue of involvement of unitary (entangled) quantum states during pre-conscious quantum
computation and the unity of quantum information selected in each objective reduction, the issue of
binding may be resolved.
Regarding the transitions from pre-conscious processes to consciousness itself, the pre-conscious
processes may equate to the quantum superposition/quantum computation phase, and consciousness
itself to the actual (instantaneous) objective reduction events. Consciousness may then be seen as a
sequence of discrete events (e.g. at 40 Hz).
As Penrose objective reductions are proposed to be non-computable (reflecting influences from
space-time geometry which are neither random, nor algorithmic) conscious choices and understanding
may be similarly non-computable.
Free will may be seen as a combination of deterministic pre-conscious processes acted on by a
non-computable influence.
Subjective time flow derives from a sequence of irreversible quantum state reductions.
Could objective reduction be occurring in the brain? If so (from E = h/T) time T would be expected to coincide
with known neurophysiological processes with time scales from tens to hundreds of milliseconds (e.g. 25 msec
for coherent 40 Hz, 100 msec for alpha EEG, 500 msec for sensory threshold events such as Libet's famous
1979 experiments). In what types of brain structures might quantum computation with objective reduction
occur? For T in this range we can calculate (from E = h/T, and with E related to mass m as described in
Hameroff and Penrose, 1996a) that superpositioned mass m in the nanogram range would be required for
conscious events of 40 to 500 msec. What brain components in nanogram quantitites could support quantum
computation and objective reduction? What is m?
Figure 16. A type of van der Waals force, the London dispersion force, is quantum mechanical and governs
both protein conformation.
Figure 17. A. An anesthetic gas molecule (A) in a hydrophobic pocket of critical brain protein (receptors,
channels, tubulin etc.) prevents normally occurring London forces, preventing protein conformational dynamics
and superposition necessary for consciousness. B. A psychedelic hallucinogen (P) acts in hydrophobic pocket in
critical brain protein to promote and sustain superposition, 'expanding' consciousness (see Figure 25).
Figure 18. A. Protein qubit. A protein such as tubulin can exist in two conformations determined by quantum
London forces in hydrophobic pocket (top), or superposition of both conformations (bottom). B. The protein
qubit corresponds to two alternative spacetime curvatures (top), and superposition/separation (bubble) of both
curvatures (bottom).
If proteins are qubits, arrays or assemblies of proteins in some type of organelle or biomolecular structure
could be a quantum computer. Ideal structures would be:
Abundant;
Capable of information processing and computation;
Functionally important (e.g., regulating synapses);
Self-organizing;
Tunable by input information (e.g., microtubule-associated protein orchestration);
Periodic and crystal-like in structure (e.g., dipole lattice);
Isolated (transiently) from environmental decoherence;
Conformationally coupled to quantum events (e.g., London forces);
Cylindrical wave-guide structure; and,
Plasma-like charge layer coating.
While various structures/organelles have been suggested (e.g., membrane proteins, clathrins, myelin,
pre-synaptic grids, and calcium ions), the most logical candidates are microtubule automata.
Figure 19. The Penrose-Hameroff Orch OR model was hatched on a hike in the Grand Canyon following the
Tucson I conference in April, 1994. From left: David Chalmers, Rhett Savage, Marie-Francoise Insinna, Seamus
O'Morain, Stuart Hameroff, Roger Penrose, Vanessa Penrose, Jeff Tollaksen. Photo by Ezio Insinna.
Tubulin subunits within microtubules act as qubits, switching between states on a nanosecond (10 sec)
scale governed by quantum London forces in hydrophobic pockets;
Tubulin qubits interact computationally by nonlocal quantum entanglement according to the Schrodinger
equation;
Figure 20. The basic idea in the Orch OR model is that each tubulin in a microtubule is a qubit.
Figure 21. Microtubule automaton sequence simulation in which classical computing (step 1) leads to
emergence of quantum coherent superposition (steps 2-6) in certain (gray) tubulins due to pattern resonance.
Step 6 (in coherence with other microtubule tubulins) meets critical threshold related to quantum gravity for
self-collapse (Orch OR). Consciousness (Orch OR) occurs in the step 6 to 7 transition. Step 7 represents the
eigenstate of mass distribution of the collapse which evolves by classical computing automata to regulate
neural function. Quantum coherence begins to re-emerge in step 8.
pre-conscious processing which continues until the threshold for objective reduction (OR) is reached by
E = h/T;
At that instant collapse, or OR occurs which is an actual event in fundamental space-time geometry.
This event selects a particular configuration of Planck-scale experiential geometry, enacting a "moment
of awareness," "occasion of experience" or conscious event.
Figure 22. Schematic graph of proposed pre-conscious quantum superposition (number of tubulins) emerging
versus time in microtubules. Area under curve connects superposed mass energy E with collapse time T in
accordance with E=(h/T. E may be expressed as n , the number of tubulins whose mass separation (and
t
separation of underlying space time) for time T will self-collapse. For T = 25 msec (e.g. 40 Hz oscillations), n
10
= 2 x 10
tubulins.
Figure 23. Schematic of quantum computation of three tubulins which begin (left) in initial classical states,
then enter isolated quantum superposition in which all possible states coexist. After reduction, one particular
classical outcome state is chosen (right).
Figure 24. Schematic quantum computation in spacetime curvature for three mass distributions (e.g. tubulin
conformations in Figure 23) which begin (left) in initial classical states, then enter isolated quantum
superposition in which all possible states coexist. After reduction, one particular classical outcome state is
chosen (right).
A sequence of OR events (e.g. at 40 Hz) provides a forward flow of subjective time and "stream" of
consciousness;
Figure 25. Quantum superposition/entanglement in microtubules for 5 states related to consciousness. Area
under each curve equivalent in all cases. A. Normal 30 Hz experience: as in Figure 22. B. Anesthesia:
anesthetics bind in hydrophobic pockets and prevent quantum delocalizability and coherent superposition. C.
Heightened Experience: increased sensory experience input (for example) increases rate of emergence of
quantum superposition. Orch OR threshold is reached faster, and Orch OR frequency increases. D. Altered
State: even greater rate of emergence of quantum superposition due to sensory input and other factors
promoting quantum state (e.g. meditation, psychedelic drug etc.). Predisposition to quantum state results in
baseline shift and collapse so that conscious experience merges with normally sub-conscious quantum
computing mode. E. Dreaming: prolonged sub-threshold quantum superposition time.
At the nanoscale each event determines new classical states of microtubule automata which regulate
synaptic and other neural functions;
During the pre-conscious quantum superposition/computation phase, oscillations are "tuned" and
"orchestrated" by microtubule-associated proteins (MAPs), providing a feedback loop between the
biological system and the quantum state (hence Orch OR);
Quantum states in microtubules may link to those in microtubules in other neurons and glia by tunneling
through gap junctions, permitting extension of the quantum state throughout significant volumes of the
brain.
Figure 26. Schematic of proposed quantum superposition and entanglement in microtubules in three
dendrites interconnected by tunneling through gap junctions. Within each neuronal dendrite, microtubuleassociated-protein (MAP) attachments breach isolation and prevent quantum coherence; MAP attachment sites
thus act as "nodes" which tune and orchestrate quantum oscillations and set possibilities and probabilities for
collapse outcomes (orchestrated objective reduction: Orch OR). Gap junctions may enable quantum tunneling
among dendrites resulting in macroscopic quantum states.
From E = h/T we can calculate the size and extension of Orch OR events which correlate with subjective or
neurophysiological descriptions of conscious events.
Event
E
15
4 x 10
Buddhist "moment of awareness" 13 ms
(4 x 10 tubulins/cell ~ 40,000
neurons)
15
2 x 10
"Coherent 40 Hz" oscillations"
25 ms
100 ms
500ms
nucleons
10
nucleons
10
(2 x 10 tubulins/cell ~ 20,000
neurons)
14
5 x 10
nucleons
10
nucleons
But how could delicate quantum superposition/computation be isolated from environmental decoherence in the
brain (generally considered to be a noisy thermal bath) while also communicating (input/output) with the
environment? One possibility is that quantum superposition/computation occurs in an isolation phase which
alternates with a communicative phase, for example at 40 Hz. One of the most primitive biological functions is
the transition of cytoplasm between a liquid, solution ("sol") phase, and a solid, gelatinous ("gel") phase due to
assembly and disassembly of the cytoskeletal protein actin. Actin sol-gel transitions can occur at 40 Hz or
Figure 27. Immunoelectron micrograph of cytoplasm showing microtubules (arrows), intermediate filaments
(arrowheads) and actin microfilaments (mf). Dense gel of actin (lower left) completely obscures (?isolates)
microtubules. Actin sol-gel transitions can occur at 40 Hz or faster. Scale bar (upper right): 500 nanometers.
With permission from Svitkina et al, 1995.
Plasma phase sleeves (Sackett);
Figure 28. Dan Sackett at NIH recently described a plasma-like sleeve of charged ions surrounding
microtubules at precisely optimal pH.
Quantum excitations/ordering of surrounding water (Jibu/Yasue/Hagan);
Hydrophobic pockets;
Hollow microtubule cores;
Laser-like pumping, including environment (Frohlich, Conrad).
Quantum error correcting codes
Another apparent obstacle to the Orch OR proposal is how the weak energy involved in the gravitational
collapse can be influential. For a detailed description of this problem and potential solutions, see Hameroff,
1998c. One possibility is that the gravitational self-energy is delivered to the involved tubulins via London
forces virtually instantaneously (e.g. within one Planck time) so that the power (energy/time) is significant approximately one kilowatt per tubulin per Orch OR event.
she is Carol! (an immense number of possibilities could be superposed in a human brain's 10
tubulins).
Figure 29. Face recognition. A familiar face induces superposition (left) of three possible solutions (Amy,
Betty, Carol) which "collapse" to the correct answer Carol (right). Volitional choice. Three possible dinner
selections (shrimp, sushi, pasta) are considered in superposition (left), and collapse via Orch OR to choice of
sushi (right).
In a volitional act possible choices may be superposed. Suppose for example you are selecting dinner from a
menu. During pre-conscious processing, shrimp, sushi and pasta are superposed in a quantum computation.
As threshold for objective reduction is reached, the quantum state reduces to a single classical state. A choice
is made. You'll have sushi!
How does the choice actually occur? In a conventional neural network scheme, the selection criteria can be
described by a deterministic algorithm which precludes the possibility of free will. The non-computable
influence in Orch OR may be useful in understanding free will.
The problem in understanding free will is that our actions seem neither totally deterministic nor random
(probabilistic). What else is there in nature? As previously described, in OR (and Orch OR) the reduction
outcomes are neither deterministic nor probabilistic, but involve a factor which is "non-computable." The
microtubule quantum superposition evolves linearly (analogous to a quantum computer) but is influenced at
the instant of collapse by hidden non-local variables (quantum-mathematical logic inherent in fundamental
spacetime geometry). The possible outcomes are limited, or probabilities set ("orchestrated"), by
neurobiological feedback (in particular microtubule associated proteins, or MAPs). The precise outcome3/4our
free will actions3/4are chosen by effects of the hidden logic on the quantum system poised at the edge of
objective reduction.
Figure 30. Free will may be seen as the result of deterministic processes (behavior of trained robot
windsurfer) acted on repeatedly by non-computable influences, here represented as a seemingly capricious
wind.
Consider a sailboard analogy for free will. A sailor sets the sail in a certain way; the direction the board sails is
determined by the action of the wind on the sail. Let's pretend the sailor is a non-conscious robot zombie run
by a quantum computer which is trained and programmed to sail. Setting and adjusting of the sail, sensing the
wind and position, jibing and tacking (turning the board) are algorithmic and deterministic, and may be
analogous to the pre-conscious, quantum computing phase of Orch OR. The direction and intensity of the wind
(seemingly capricious, or unpredictable) may be considered analogous to Planck scale hidden non-local
variables (e.g. "Platonic" quantum-mathematical logic inherent in space-time geometry). The choice, or
outcome (the direction the boat sails, the point on shore it lands) depends on the deterministic sail settings
acted on repeatedly by the apparently unpredictable wind. Our "free will" actions could be the net result of
deterministic processes acted on by hidden quantum logic at each Orch OR event. This can explain why we
generally do things in an orderly, deterministic fashion, but occasionally our actions or thoughts are surprising,
even to ourselves.
approximately 10 tubulins, so T would be 50,000 msec, or nearly one minute. This seems unlikely. Larger
9
organisms such as the nematode worm (e.g., C. elegans) with 300 neurons (3 x 10 tubulins) would need to
maintain quantum isolation for only 133 msec - not unreasonable. Such organisms (tiny worms and urchins)
were prevalent at the beginning of the "Cambrian explosion," a burst of evolution which occurred 540 million
years ago. Did primitive consciousness (via Orch OR) accelerate evolution and precipitate the Cambrian
explosion?
The Cambrian
explosion was a
burst of evolution
540 million years
ago. Organisms
present at the
Cambrian onset
included small
worms and
urchins. Did
consciousness
(Orch OR) cause
the Cambrian
explosion?
Figure 32. Organisms present at the early Cambrian explosion (e.g. tiny urchins, worms and suctorians) are
the right size for primitive consciousness by Orch OR.
Figure 33. Actinosphaerium is a tiny urchin like those present at the early Cambrian explosion. Each has
9
about one hundred rigid axonemes about 300 microns long, made up of a total of about 3 x 10 tubulins (with
permission from L.E. Roth).
Figure 34. Cross-section of single axoneme of actinosphaerium - a double spiral array of interconnected
microtubules. Scale bar: 500 nm (with permission from L.E. Roth).
Would consciousness be advantageous to survival (above and beyond intelligent, complex behavior)? It seems
that, yes, consciousness would indeed be advantageous to survival, and hence capable of accelerating
evolution. Non-computable behavior (unpredictability, intuitive actions) would be beneficial in predator-prey
relations. Having conscious experience of taste would promote finding food; the experience of pain would
promote avoiding predators. And the pleasurable qualia of sex would promote reproduction.
So "what is it like to be a worm?" Lacking our sensory apparatus, associative memory and complex nervous
system such primitive consciousness would be a mere glimmer, a disjointed smudge of reality. But
qualitatively, at a basic level, such primitive consciousness would be akin to ours.
What about future evolution? Will consciousness occur in computers? The advent of quantum computers opens
the possibility, however as presently envisioned quantum computers will have insufficient mass in
superposition (e.g. electrons) to reach threshold for objective reduction. Instead, superpositions will be
disrupted by environmental decoherence. Conceivably, future generations of quantum computers could satisfy
requirements for objective reduction and consciousness.
10. Conclusions
Brain processes relevant to consciousness extend downward within neurons to the level of cytoskeletal
microtubules.
An explanation for conscious experience requires (in addition to neuroscience and psychology) a modern
form of pan-protopsychism in which proto-conscious qualia are embedded in the basic level of reality, as
described by modern physics.
Roger Penrose's physics of objective reduction (OR) connects brain structures to fundamental reality,
leading to the Penrose-Hameroff model of quantum computation with objective reduction in
microtubules (orchestrated objective reduction: Orch OR).
The Orch OR model is consistent with known neurophysiological processes, generates testable
predictions, and is the type of fundamental, multi-level, interdisciplinary theory which may account for
the mind's enigmatic features.
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